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Two-photon (2P) microscopy is a powerful technique for deep-tissue fluorescence imaging; however, tissue scattering limits its effectiveness for depth imaging using conventional approaches. Despite typical strategies having been put forward…

Optics · Physics 2025-05-21 Lei Zhu , Bernhard Rauer , Hilton B. De Aguiar , Sylvain Gigan

The scheme of optical imaging using scattering lens can provide a resolution beyond the classical optical diffraction limit with a coherent-state input. Nevertheless, due to the shot noise of the coherent state, the corresponding…

Quantum Physics · Physics 2021-04-20 Dong Li , Yao Yao

Photoacoustic tomography is an emerging medical imaging technology whose primary aim is to map the high-contrast optical properties of biological tissues by leveraging high-resolution ultrasound measurements. Mathematically, this can be…

Analysis of PDEs · Mathematics 2025-02-14 Alessandro Felisi

Ultrasound imaging is widely used for real-time, noninvasive diagnosis, but speckle and related artifacts reduce image quality and can hinder interpretation. We present a diffusion-based ultrasound despeckling method built on the Image…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Shuoqi Chen , Yujia Wu , Geoffrey P. Luke

Sensing and manipulating targets hidden under scattering media are universal problems that take place in applications ranging from deep-tissue optical imaging to laser surgery. A major issue in these applications is the shallow light…

Optical spectroscopy is a fundamental tool in numerous areas of science and technology. Much effort has focused on miniaturizing spectrometers, but thus far at the cost of high spectral resolution and broad operating range. Here, we…

Speckle noise is an inherent disturbance in coherent imaging systems such as digital holography, synthetic aperture radar, optical coherence tomography, or ultrasound systems. These systems usually produce only single observation per view…

Image and Video Processing · Electrical Eng. & Systems 2022-05-19 Tsung-Ming Tai , Yun-Jie Jhang , Wen-Jyi Hwang , Chau-Jern Cheng

The wavefront is scrambled when coherent light propagates through a random scattering medium and which makes direct use of the conventional optical methods ineffective. In this paper, we propose and demonstrate a structured light…

Speckles arise when coherent light interacts with biological tissues. Information retrieval from speckles is desired yet challenging, requiring understanding or mapping of the multiple scattering process, or reliable capability to reverse…

Image and Video Processing · Electrical Eng. & Systems 2020-05-05 Huanhao Li , Zhipeng Yu , Yunqi Luo , Shengfu Cheng , Lihong V. Wang , Yuanjin Zheng , Puxiang Lai

The imaging depth of deep-tissue optical microscopy is governed by the performance of the gating operation that suppresses the multiply scattered waves obscuring the ballistic waves. Although various gating operations based on confocal,…

Snapshot spectral imaging is rapidly gaining interest for remote sensing applications. Acquiring spatial and spectral data within one image promotes fast measurement times, and reduces the need for stabilized scanning imaging systems. Many…

Image and Video Processing · Electrical Eng. & Systems 2018-12-05 Rebecca French , Sylvain Gigan , Otto L. Muskens

Imaging inside scattering media at optical resolution is a longstanding challenge affecting multiple fields, from bio-medicine to astronomy. In recent years, several groundbreaking techniques for imaging inside scattering media, in…

Optics · Physics 2024-05-17 Elad Sunray , Gil Weinberg , Moriya Rosenfeld , Ori Katz

There has been devoted significant mathematical research to model the light propagation in tissue and to recover the absorption and scattering coefficients after photoacoustic inversion. Typically, the basic light propagation models…

Mathematical Physics · Physics 2012-07-02 Peter Elbau , Otmar Scherzer

In turbid media, scattering of light scrambles information of the incident beam and represents an obstacle to optical imaging. Noninvasive imaging through opaque layers is challenging for dynamic and wide-field objects due to unreliable…

Optics · Physics 2018-10-17 Yuan Yuan , Hui Chen

Optical detection of nanoscale objects without relying on fluorescence is a current challenge due to their extremely weak interaction with light. Resonator-enhanced absorption microscopy is a novel tool to heavily boost the light-matter…

Imaging below the diffraction limit is always a public interest because of the restricted resolution of conventional imaging systems. To beat the limit, evanescent harmonics decaying in space must participate in the imaging process. Here,…

Optics · Physics 2019-10-02 Tie-Jun Huang , Li-Zheng Yin , Ya Shuang , Jiang-Yu Liu , Yunhua Tan , Pu-Kun Liu

In optical imaging, light propagation is affected by the inhomogeneities of the medium. Sample-induced aberrations and multiple scattering can strongly degrade the image resolution and contrast. Based on a dynamic correction of the incident…

Despite its wide use in medicine, ultrasound imaging faces several challenges related to its poor signal-to-noise ratio and several sources of noise and artefacts. Enhancing ultrasound image quality involves balancing concurrent factors…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Yuxin Zhang , Clément Huneau , Jérôme Idier , Diana Mateus

The inherent non-linearity of intensity correlation functions can be used to spatially distinguish identical emitters beyond the diffraction limit, as achieved, for example, in Super-Resolution Optical Fluctuation Imaging (SOFI). Here, we…

Optics · Physics 2024-12-18 Yifan Chen , Chieh Tsao , Hendrik Utzat

Coherent diffractive imaging is unique as the only route for achieving diffraction-limited spatial resolution in the extreme ultraviolet and X-ray regions, limited only by the wavelength of the light. Recently, advances in coherent short…

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