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Type 1 diabetes (T1D) is an autoimmune disorder that leads to the destruction of insulin-producing cells, resulting in insulin deficiency, as to why the affected individuals depend on external insulin injections. However, insulin can…

Machine Learning · Computer Science 2026-04-27 Beyza Cinar , Maria Maleshkova

Type 1 Diabetes (T1D) is an autoimmune disease leading to insulin insufficiency. Thus, patients require lifelong insulin therapy, which has a side effect of hypoglycemia. Hypoglycemia is a critical state of decreased blood glucose levels…

Machine Learning · Computer Science 2026-01-21 Beyza Cinar , Louisa van den Boom , Maria Maleshkova

Type 1 diabetes (T1D) management can be significantly enhanced through the use of predictive machine learning (ML) algorithms, which can mitigate the risk of adverse events like hypoglycemia. Hypoglycemia, characterized by blood glucose…

Quantitative Methods · Quantitative Biology 2025-04-02 Beyza Cinar , Jennifer Daniel Onwuchekwa , Maria Maleshkova

Individualized therapy is driven forward by medical data analysis, which provides insight into the patient's context. In particular, for Type 1 Diabetes (T1D), which is an autoimmune disease, relationships between demographics, sensor data,…

Signal Processing · Electrical Eng. & Systems 2026-04-23 Beyza Cinar , Maria Maleshkova

Diabetes mellitus is a global health crisis characterized by poor blood sugar regulation, impacting millions of people worldwide and leading to severe complications and mortality. Although Type 1 Diabetes Mellitus (T1DM) has a lower number…

Other Quantitative Biology · Quantitative Biology 2025-04-14 Rinrada Jadsadaphongphaibool , Dadi Bi , Christian D. Lorenz , Yansha Deng , Robert Schober

The dead-in-bed syndrome describes the sudden and unexplained death of young individuals with Type 1 Diabetes (T1D) without prior long-term complications. One leading hypothesis attributes this phenomenon to nocturnal hypoglycemia (NH), a…

Machine Learning · Computer Science 2025-04-15 Marco Voegeli , Sonia Laguna , Heike Leutheuser , Marc Pfister , Marie-Anne Burckhardt , Julia E Vogt

Type 1 Diabetes is a chronic autoimmune condition in which the immune system attacks and destroys insulin-producing beta cells in the pancreas, resulting in little to no insulin production. Insulin helps glucose in your blood enter your…

Quantitative Methods · Quantitative Biology 2025-02-04 Soon Jynn Chu , Nalaka Amarasiri , Sandesh Giri , Priyata Kafle

Diabetes is a chronic metabolic disorder characterized by elevated blood glucose levels due to impaired insulin production or function. Two main forms are recognized: type 1 diabetes (T1D), which involves autoimmune destruction of…

Genomics · Quantitative Biology 2026-02-11 Maria De La Luz Lomboy Toledo , Daniel Onah

Effective management of Type 1 Diabetes requires continuous glucose monitoring and precise insulin adjustments to prevent hyperglycemia and hypoglycemia. With the growing adoption of wearable glucose monitors and mobile health applications,…

Machine Learning · Computer Science 2026-01-22 Giorgia Rigamonti , Mirko Paolo Barbato , Davide Marelli , Paolo Napoletano

The classification of diabetes and prediabetes by static glucose thresholds obscures the pathophysiological dysglycemia heterogeneity, primarily driven by insulin resistance (IR), beta-cell dysfunction, and incretin deficiency. This review…

Machine Learning · Computer Science 2025-11-07 Ahmed A. Metwally , Heyjun Park , Yue Wu , Tracey McLaughlin , Michael P. Snyder

Background: This study investigates glucose conditions preceding and following various hypoglycemia levels in individuals with type 1 diabetes using open-source automated insulin delivery (AID) systems. It also seeks to evaluate…

Quantitative Methods · Quantitative Biology 2024-05-16 Arsalan Shahid , Dana M. Lewis

A task of vital clinical importance, within Diabetes management, is the prevention of hypo/hyperglycemic events. Increasingly adopted Continuous Glucose Monitoring (CGM) devices offer detailed, non-intrusive and real time insights into a…

Machine Learning · Computer Science 2023-03-09 Jakub J. Dylag

Due to the sensitive nature of diabetes-related data, preventing them from being shared between studies, progress in the field of glucose prediction is hard to assess. To address this issue, we present GLYFE (GLYcemia Forecasting…

Signal Processing · Electrical Eng. & Systems 2020-06-30 Maxime De Bois , Mehdi Ammi , Mounîm A. El Yacoubi

Understanding how biomarker distributions evolve over time is a central challenge in digital health and chronic disease monitoring. In diabetes, changes in the distribution of glucose measurements can reveal patterns of disease progression…

Machine Learning · Statistics 2026-03-26 Antonio Álvarez-López , Marcos Matabuena

Diabetes mellitus is a disease that affects to hundreds of millions of people worldwide. Maintaining a good control of the disease is critical to avoid severe long-term complications. In recent years, several artificial pancreas systems…

Neural and Evolutionary Computing · Computer Science 2023-05-09 J. Ignacio Hidalgo , J. Manuel Colmenar , José L. Risco-Martín , Alfredo Cuesta-Infante , Esther Maqueda , Marta Botella , José Antonio Rubio

Managing Type 1 diabetes (T1D) aims to optimize glucose levels within the target range while minimizing hyperglycemia and hypoglycemia. Exercise presents additional challenges due to complex effects on glucose dynamics. Despite advancements…

Quantitative Methods · Quantitative Biology 2025-04-03 Ahtsham Zafar , Abiodun Solanke , Dana M. Lewis , Arsalan Shahid

Daytime hypoglycemia should be accurately predicted to achieve normoglycemia and to avoid disastrous situations. Hypoglycemia, an abnormally low blood glucose level, is divided into daytime hypoglycemia and nocturnal hypoglycemia. Many…

Machine Learning · Statistics 2017-05-01 Miyeon Jung , You-Bin Lee , Sang-Man Jin , Sung-Min Park

Background: Accurate week-ahead forecasts of continuous glucose monitoring (CGM) derived metrics could enable proactive diabetes management, but relative performance of modern tabular learning approaches is incompletely defined. Methods: We…

Other Quantitative Biology · Quantitative Biology 2026-01-05 Simon Lebech Cichosz , Stine Hangaard , Thomas Kronborg , Peter Vestergaard , Morten Hasselstrøm Jensen

Type 1 Diabetes (T1D) affects millions worldwide, requiring continuous monitoring to prevent severe hypo- and hyperglycemic events. While continuous glucose monitoring has improved blood glucose management, deploying predictive models on…

Machine Learning · Computer Science 2025-11-27 Mirko Paolo Barbato , Giorgia Rigamonti , Davide Marelli , Paolo Napoletano

Patients with Type I Diabetes (T1D) must take insulin injections to prevent the serious long term effects of hyperglycemia - high blood glucose (BG). Patients must also be careful not to inject too much insulin because this could induce…

Machine Learning · Computer Science 2019-04-01 Neil C. Borle , Edmond A. Ryan , Russell Greiner
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