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The detection of rare variants is important for understanding the genetic heterogeneity in mixed samples. Recently, next-generation sequencing (NGS) technologies have enabled the identification of single nucleotide variants (SNVs) in mixed…

Genomics · Quantitative Biology 2016-04-25 Fan Zhang , Patrick Flaherty

We introduce incremental variational inference and apply it to latent Dirichlet allocation (LDA). Incremental variational inference is inspired by incremental EM and provides an alternative to stochastic variational inference. Incremental…

Machine Learning · Statistics 2015-07-23 Cedric Archambeau , Beyza Ermis

Aligning Large Language Models (LLM) to address subjectivity and nuanced preference levels requires adequate flexibility and control, which can be a resource-intensive and time-consuming procedure. Existing training-time alignment methods…

The mixture cure rate model is the most commonly used cure rate model in the literature. In the context of mixture cure rate model, the standard approach to model the effect of covariates on the cured or uncured probability is to use a…

Methodology · Statistics 2022-08-23 Suvra Pal , Yingwei Peng , Sandip Barui , Pei Wang

Audio-visual emotion recognition (AVER) methods typically fuse utterance-level features, and even frame-level attention models seldom address the frame-rate mismatch across modalities. In this paper, we propose a Transformer-based framework…

Multimedia · Computer Science 2026-03-13 Inyong Koo , yeeun Seong , Minseok Son , Jaehyuk Jang , Changick Kim

Envelope models provide a sufficient dimension reduction framework for multivariate regression analysis. Bayesian inference for these models has been developed primarily using Markov chain Monte Carlo (MCMC) methods. Specifically, Gibbs…

Methodology · Statistics 2026-03-03 Seunghyeon Kim , Kwangmin Lee , Yeonhee Park

While deep learning models have shown strong performance in simulating neural responses, they often fail to clearly separate stable visual encoding from condition-specific adaptation, which limits their ability to generalize across stimuli…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Qi Xu , Shuai Gong , Xuming Ran , Haihua Luo , Yangfan Hu

In real-world scenarios, although data entities may possess inherent relationships, the specific graph illustrating their connections might not be directly accessible. Latent graph inference addresses this issue by enabling Graph Neural…

Machine Learning · Computer Science 2023-11-21 Yuan Lu , Haitz Sáez de Ocáriz Borde , Pietro Liò

Large language models struggle to accumulate evidence across multiple rounds of user interaction, failing to update their beliefs in a manner consistent with Bayesian inference. Existing solutions require fine-tuning on sensitive user…

Computation and Language · Computer Science 2026-04-07 Fangzhou Lin , Peiran Li , Shuo Xing , Siyuan Yang , Qianwen Ge , Kazunori Yamada , Ziming Zhang , Haichong Zhang , Zhengzhong Tu

Bayesian methods have proved powerful in many applications for the inference of model parameters from data. These methods are based on Bayes' theorem, which itself is deceptively simple. However, in practice the computations required are…

Methodology · Statistics 2020-07-10 Michael A. Chappell , Mark W. Woolrich

We develop a convex framework for spatially varying coefficient quantile regression that, for each predictor, separates a location-invariant \emph{global} effect from a \emph{spatial deviation}. An adaptive group penalty selects whether a…

Methodology · Statistics 2025-11-26 Hou Jian , Meng Tan , Tian Maozai

Expectation maximization (EM) is a technique for estimating maximum-likelihood parameters of a latent variable model given observed data by alternating between taking expectations of sufficient statistics, and maximizing the expected log…

Methodology · Statistics 2018-07-10 Donna Henderson , Gerton Lunter

Recently, discrete latent variable models have received a surge of interest in both Natural Language Processing (NLP) and Computer Vision (CV), attributed to their comparable performance to the continuous counterparts in representation…

Computation and Language · Computer Science 2022-11-08 Erxin Yu , Lan Du , Yuan Jin , Zhepei Wei , Yi Chang

Variational inference is a general framework to obtain approximations to the posterior distribution in a Bayesian context. In essence, variational inference entails an optimization over a given family of probability distributions to choose…

Statistics Theory · Mathematics 2025-07-24 Janis Keck

We present a latent variable model for predicting the relationship between a pair of text sequences. Unlike previous auto-encoding--based approaches that consider each sequence separately, our proposed framework utilizes both sequences…

Computation and Language · Computer Science 2019-06-05 Jihun Choi , Taeuk Kim , Sang-goo Lee

We present an hp-adaptive virtual element method (VEM) based on the hypercircle method of Prager and Synge for the approximation of solutions to diffusion problems. We introduce a reliable and efficient a posteriori error estimator, which…

Numerical Analysis · Mathematics 2021-11-30 Franco Dassi , Joscha Gedicke , Lorenzo Mascotto

Structural equation models (SEMs) are commonly used to study the structural relationship between observed variables and latent constructs. Recently, Bayesian fitting procedures for SEMs have received more attention thanks to their potential…

Methodology · Statistics 2024-07-12 Khue-Dung Dang , Luca Maestrini , Francis K. C. Hui

Variational autoencoders model high-dimensional data by positing low-dimensional latent variables that are mapped through a flexible distribution parametrized by a neural network. Unfortunately, variational autoencoders often suffer from…

Machine Learning · Statistics 2023-01-03 Yixin Wang , David M. Blei , John P. Cunningham

Adaptive voter models (AVMs) are simple mechanistic systems that model the emergence of mesoscopic structure from local networked processes driven by conflict and homophily. AVMs display rich behavior, including a phase transition from a…

Physics and Society · Physics 2020-03-16 Philip S. Chodrow , Peter J. Mucha

We propose a single neural probabilistic model based on variational autoencoder that can be conditioned on an arbitrary subset of observed features and then sample the remaining features in "one shot". The features may be both real-valued…

Machine Learning · Statistics 2019-07-01 Oleg Ivanov , Michael Figurnov , Dmitry Vetrov