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We introduce findings and methods to facilitate evidence-based discussion about how large language models (LLMs) should behave in response to user signals of risk of suicidal thoughts and behaviors (STB). People are already using LLMs as…

Human-Computer Interaction · Computer Science 2025-11-03 Nick Judd , Alexandre Vaz , Kevin Paeth , Layla Inés Davis , Milena Esherick , Jason Brand , Inês Amaro , Tony Rousmaniere

We introduce a multi-turn benchmark for evaluating personalised alignment in LLM-based AI assistants, focusing on their ability to handle user-provided safety-critical contexts. Our assessment of ten leading models across five scenarios…

Human-Computer Interaction · Computer Science 2025-01-31 Lize Alberts , Benjamin Ellis , Andrei Lupu , Jakob Foerster

Amidst the growing interest in developing task-autonomous AI for automated mental health care, this paper addresses the ethical and practical challenges associated with the issue and proposes a structured framework that delineates levels of…

Computers and Society · Computer Science 2024-08-16 Declan Grabb , Max Lamparth , Nina Vasan

The deployment of large language models (LLMs) as interactive agents has exposed a category of behavioral failure that prevailing terminology, principally hallucination, fails to adequately characterize. This paper introduces LLM Psychosis…

Computers and Society · Computer Science 2026-04-30 Ashutosh Raj

As Large Language Models are rapidly deployed across diverse applications from healthcare to financial advice, safety evaluation struggles to keep pace. Current benchmarks focus on single-turn interactions with generic policies, failing to…

Cryptography and Security · Computer Science 2025-10-28 Madhur Jindal , Hari Shrawgi , Parag Agrawal , Sandipan Dandapat

Large language model (LLM) chatbots are susceptible to biases and hallucinations, but current evaluations of mental wellness technologies lack comprehensive case studies to evaluate their practical applications. Here, we address this gap by…

Human-Computer Interaction · Computer Science 2024-07-17 Lucia Chen , David A. Preece , Pilleriin Sikka , James J. Gross , Ben Krause

Recent advancements in large language models (LLMs) promise to expand mental health interventions by emulating therapeutic techniques, potentially easing barriers to care. Yet there is a lack of real-world empirical evidence evaluating the…

Human-Computer Interaction · Computer Science 2025-01-28 Yinzhou Wang , Yimeng Wang , Ye Xiao , Liabette Escamilla , Bianca Augustine , Kelly Crace , Gang Zhou , Yixuan Zhang

Background: While Large Language Models (LLMs) have achieved widespread adoption, malicious prompt engineering specifically "jailbreak attacks" poses severe security risks by inducing models to bypass internal safety mechanisms. Current…

Computers and Society · Computer Science 2026-01-21 Chutian Huang , Dake Cao , Jiacheng Ji , Yunlou Fan , Chengze Yan , Hanhui Xu

Ramaswamy et al. reported in Nature Medicine that ChatGPT Health under-triages 51.6% of emergencies, concluding that consumer-facing AI triage poses safety risks. However, their evaluation used an exam-style protocol -- forced A/B/C/D…

Human-Computer Interaction · Computer Science 2026-03-27 David Fraile Navarro , Farah Magrabi , Enrico Coiera

Background Large language models (LLMs) are increasingly deployed in medical consultations, yet their safety under realistic user pressures remains understudied. Prior assessments focused on neutral conditions, overlooking vulnerabilities…

Computation and Language · Computer Science 2026-01-16 Vahideh Zolfaghari

Several recent works have argued that Large Language Models (LLMs) can be used to tame the data deluge in the cybersecurity field, by improving the automation of Cyber Threat Intelligence (CTI) tasks. This work presents an evaluation…

Cryptography and Security · Computer Science 2025-11-13 Emanuele Mezzi , Fabio Massacci , Katja Tuma

Large language models are rapidly being deployed as AI tutors, yet current evaluation paradigms assess problem-solving accuracy and generic safety in isolation, failing to capture whether a model is simultaneously pedagogically effective…

Computation and Language · Computer Science 2026-03-19 Rima Hazra , Bikram Ghuku , Ilona Marchenko , Yaroslava Tokarieva , Sayan Layek , Somnath Banerjee , Julia Stoyanovich , Mykola Pechenizkiy

Large language models (LLMs) have emerged as powerful tools for addressing a wide range of general inquiries and tasks. Despite this, fine-tuning aligned LLMs on smaller, domain-specific datasets, critical to adapting them to specialized…

Artificial Intelligence · Computer Science 2025-02-04 Guanlin Li , Kangjie Chen , Shangwei Guo , Jie Zhang , Han Qiu , Chao Zhang , Guoyin Wang , Tianwei Zhang , Jiwei Li

Large Language Models (LLMs) demonstrate complex responses to threat-based manipulations, revealing both vulnerabilities and unexpected performance enhancement opportunities. This study presents a comprehensive analysis of 3,390…

Cryptography and Security · Computer Science 2025-07-30 Atil Samancioglu

Role-playing enables large language models (LLMs) to engage users in immersive and personalized interactions, but it also introduces significant safety risks. Existing role-play fine-tuning techniques improve role adaptability but may…

Computation and Language · Computer Science 2025-05-28 Weixiang Zhao , Yulin Hu , Yang Deng , Jiahe Guo , Xingyu Sui , Xinyang Han , An Zhang , Yanyan Zhao , Bing Qin , Tat-Seng Chua , Ting Liu

Large Language Model (LLMs) such as ChatGPT that exhibit generative AI capabilities are facing accelerated adoption and innovation. The increased presence of Generative AI (GAI) inevitably raises concerns about the risks and safety…

Computers and Society · Computer Science 2024-07-29 Jaymari Chua , Yun Li , Shiyi Yang , Chen Wang , Lina Yao

Large Language Models (LLMs) are rapidly transitioning from conversational assistants to autonomous agents embedded in critical organizational functions, including Security Operations Centers (SOCs), financial systems, and infrastructure…

Cryptography and Security · Computer Science 2026-01-06 Giuseppe Canale , Kashyap Thimmaraju

Instruction-tuned large language models produce helpful, structured responses, but how robust is this helpfulness under trivial constraints? We show that simple lexical constraints (banning a single punctuation character or common word)…

Computation and Language · Computer Science 2026-04-28 Erfan Baghaei Potraghloo , Seyedarmin Azizi , Souvik Kundu , Massoud Pedram

While Large Language Models (LLMs) demonstrate significant potential in providing accessible mental health support, their practical deployment raises critical trustworthiness concerns due to the domains high-stakes and safety-sensitive…

Computation and Language · Computer Science 2026-03-04 Zixin Xiong , Ziteng Wang , Haotian Fan , Xinjie Zhang , Wenxuan Wang

Large language models (LLMs) are already being piloted for clinical use in hospital systems like NYU Langone, Dana-Farber and the NHS. A proposed deployment use case is psychotherapy, where a LLM-powered chatbot can treat a patient…

Computation and Language · Computer Science 2024-10-10 Saadia Gabriel , Isha Puri , Xuhai Xu , Matteo Malgaroli , Marzyeh Ghassemi