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Variational autoencoders (VAEs), that are built upon deep neural networks have emerged as popular generative models in computer vision. Most of the work towards improving variational autoencoders has focused mainly on making the…

Machine Learning · Statistics 2016-11-17 Siddharth Agrawal , Ambedkar Dukkipati

In this work, we address the lack of 3D understanding of generative neural networks by introducing a persistent 3D feature embedding for view synthesis. To this end, we propose DeepVoxels, a learned representation that encodes the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-12 Vincent Sitzmann , Justus Thies , Felix Heide , Matthias Nießner , Gordon Wetzstein , Michael Zollhöfer

We introduce an encoder-only approach to learn the evolution operators of large-scale non-linear dynamical systems, such as those describing complex natural phenomena. Evolution operators are particularly well-suited for analyzing systems…

Machine Learning · Computer Science 2025-05-27 Giacomo Turri , Luigi Bonati , Kai Zhu , Massimiliano Pontil , Pietro Novelli

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

Quantitative Methods · Quantitative Biology 2023-05-01 Louise Budzynski , Andrea Pagnani

Image classification is a difficult machine learning task, where Convolutional Neural Networks (CNNs) have been applied for over 20 years in order to solve the problem. In recent years, instead of the traditional way of only connecting the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Bin Wang , Yanan Sun , Bing Xue , Mengjie Zhang

Metric learning aims to learn a highly discriminative model encouraging the embeddings of similar classes to be close in the chosen metrics and pushed apart for dissimilar ones. The common recipe is to use an encoder to extract embeddings…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 Aleksandr Ermolov , Leyla Mirvakhabova , Valentin Khrulkov , Nicu Sebe , Ivan Oseledets

Learning representations according to the underlying geometry is of vital importance for non-Euclidean data. Studies have revealed that the hyperbolic space can effectively embed hierarchical or tree-like data. In particular, the few past…

Machine Learning · Computer Science 2023-06-16 Eric Qu , Dongmian Zou

While autoregressive Large Vision-Language Models (LVLMs) demonstrate remarkable proficiency in multimodal tasks, they face a "Visual Signal Dilution" phenomenon, where the accumulation of textual history expands the attention partition…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Siyuan Huang , Xiaoye Qu , Yafu Li , Tong Zhu , Zefeng He , Muxin Fu , Daizong Liu , Wei-Long Zheng , Yu Cheng

Massive molecular simulations of drug-target proteins have been used as a tool to understand disease mechanism and develop therapeutics. This work focuses on learning a generative neural network on a structural ensemble of a drug-target…

Machine Learning · Computer Science 2022-05-24 N. Joseph Tatro , Payel Das , Pin-Yu Chen , Vijil Chenthamarakshan , Rongjie Lai

This work presents a non-intrusive surrogate modeling scheme based on machine learning technology for predictive modeling of complex systems, described by parametrized time-dependent PDEs. For these problems, typical finite element…

Numerical Analysis · Mathematics 2021-04-26 Stefanos Nikolopoulos , Ioannis Kalogeris , Vissarion Papadopoulos

Deep learning has significantly advanced medical imaging analysis, yet variations in image resolution remain an overlooked challenge. Most methods address this by resampling images, leading to either information loss or computational…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Ashay Patel , Michela Antonelli , Sebastien Ourselin , M. Jorge Cardoso

We explore a framework for protein sequence representation learning that decomposes the task between manifold learning and distributional modelling. Specifically we present a Latent Space Diffusion architecture which combines a protein…

Machine Learning · Computer Science 2025-03-25 Eoin Quinn , Ghassene Jebali , Maxime Seince , Oliver Bent

The predominant approach for language modeling is to process sequences from left to right, but this eliminates a source of information: the order by which the sequence was generated. One strategy to recover this information is to decode…

Computation and Language · Computer Science 2021-11-01 Xuanlin Li , Brandon Trabucco , Dong Huk Park , Michael Luo , Sheng Shen , Trevor Darrell , Yang Gao

Genomic sequence analysis plays a crucial role in various scientific and medical domains. Traditional machine-learning approaches often struggle to capture the complex relationships and hierarchical structures of sequence data when working…

Machine Learning · Computer Science 2025-10-02 Sarwan Ali , Haris Mansoor , Murray Patterson

Deep learning has transformed protein design, enabling accurate structure prediction, sequence optimization, and de novo protein generation. Advances in single-chain protein structure prediction via AlphaFold2, RoseTTAFold, ESMFold, and…

Machine Learning · Computer Science 2025-02-27 Gregory W. Kyro , Tianyin Qiu , Victor S. Batista

We introduce evolutionary Kolmogorov-Arnold Networks (EvoKAN), a novel framework for solving complex partial differential equations (PDEs). EvoKAN builds on Kolmogorov-Arnold Networks (KANs), where activation functions are spline based and…

Numerical Analysis · Mathematics 2025-03-04 Guang Lin , Changhong Mou , Jiahao Zhang

It is expensive to compute residual diffusivity in chaotic in-compressible flows by solving advection-diffusion equation due to the formation of sharp internal layers in the advection dominated regime. Proper orthogonal decomposition (POD)…

Computational Physics · Physics 2019-10-02 Jiancheng Lyu , Jack Xin , Yifeng Yu

The recent years have seen a surge of interest in methods for imaging beyond the direct line of sight. The most prominent techniques rely on time-resolved optical impulse responses, obtained by illuminating a diffuse wall with an ultrashort…

Computer Vision and Pattern Recognition · Computer Science 2020-01-30 Javier Grau Chopite , Matthias B. Hullin , Michael Wand , Julian Iseringhausen

The manifold hypothesis states that high-dimensional data can be modeled as lying on or near a low-dimensional, nonlinear manifold. Variational Autoencoders (VAEs) approximate this manifold by learning mappings from low-dimensional latent…

Machine Learning · Statistics 2021-03-03 Marissa C. Connor , Gregory H. Canal , Christopher J. Rozell

Understanding protein-protein interactions is central to our understanding of almost all complex biological processes. Computational tools exploiting rapidly growing genomic databases to characterize protein-protein interactions are…

Quantitative Methods · Quantitative Biology 2016-10-28 Thomas Gueudré , Carlo Baldassi , Marco Zamparo , Martin Weigt , Andrea Pagnani
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