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The rapid advancements in large language models (LLMs) have unlocked their potential for multimodal tasks, where text and visual data are processed jointly. However, applying LLMs to medical imaging, particularly for chest X-rays (CXR),…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Nicholas Evans , Stephen Baker , Miles Reed

Following the impressive development of LLMs, vision-language alignment in LLMs is actively being researched to enable multimodal reasoning and visual IO. This direction of research is particularly relevant to medical imaging because…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Suhyeon Lee , Won Jun Kim , Jinho Chang , Jong Chul Ye

We present Chameleon, a family of early-fusion token-based mixed-modal models capable of understanding and generating images and text in any arbitrary sequence. We outline a stable training approach from inception, an alignment recipe, and…

Computation and Language · Computer Science 2025-03-24 Chameleon Team

Foundation models, trained on vast amounts of data using self-supervised techniques, have emerged as a promising frontier for advancing artificial intelligence (AI) applications in medicine. This study evaluates three different…

Multimodal Large Language Models (MLLMs) have shown success in various general image processing tasks, yet their application in medical imaging is nascent, lacking tailored models. This study investigates the potential of MLLMs in improving…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Ling Yang , Zhanyu Wang , Zhenghao Chen , Xinyu Liang , Luping Zhou

The field of advanced text-to-image generation is witnessing the emergence of unified frameworks that integrate powerful text encoders, such as CLIP and T5, with Diffusion Transformer backbones. Although there have been efforts to control…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Liang Chen , Shuai Bai , Wenhao Chai , Weichu Xie , Haozhe Zhao , Leon Vinci , Junyang Lin , Baobao Chang

In recent times, Vision-Language Models (VLMs) have been trained under two predominant paradigms. Generative training has enabled Multimodal Large Language Models (MLLMs) to tackle various complex tasks, yet issues such as hallucinations…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Wei Chow , Juncheng Li , Qifan Yu , Kaihang Pan , Hao Fei , Zhiqi Ge , Shuai Yang , Siliang Tang , Hanwang Zhang , Qianru Sun

We present LMFusion, a framework for empowering pretrained text-only large language models (LLMs) with multimodal generative capabilities, enabling them to understand and generate both text and images in arbitrary sequences. LMFusion…

Computation and Language · Computer Science 2025-02-06 Weijia Shi , Xiaochuang Han , Chunting Zhou , Weixin Liang , Xi Victoria Lin , Luke Zettlemoyer , Lili Yu

Vision-Language Pretraining (VLP) has demonstrated remarkable capabilities in learning visual representations from textual descriptions of images without annotations. Yet, effective VLP demands large-scale image-text pairs, a resource that…

Computer Vision and Pattern Recognition · Computer Science 2023-06-09 Yinda Chen , Che Liu , Wei Huang , Sibo Cheng , Rossella Arcucci , Zhiwei Xiong

We present Liquid, an auto-regressive generation paradigm that seamlessly integrates visual comprehension and generation by tokenizing images into discrete codes and learning these code embeddings alongside text tokens within a shared…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Junfeng Wu , Yi Jiang , Chuofan Ma , Yuliang Liu , Hengshuang Zhao , Zehuan Yuan , Song Bai , Xiang Bai

Despite recent progress, medical foundation models still struggle to unify visual understanding and generation, as these tasks have inherently conflicting goals: semantic abstraction versus pixel-level reconstruction. Existing approaches,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Ruiheng Zhang , Jingfeng Yao , Huangxuan Zhao , Hao Yan , Xiao He , Lei Chen , Zhou Wei , Yong Luo , Zengmao Wang , Lefei Zhang , Dacheng Tao , Bo Du

Most existing vision-language pre-training methods focus on understanding tasks and use BERT-like objectives (masked language modeling and image-text matching) during pretraining. Although they perform well in many understanding downstream…

Computer Vision and Pattern Recognition · Computer Science 2021-12-16 Tianyi Liu , Zuxuan Wu , Wenhan Xiong , Jingjing Chen , Yu-Gang Jiang

The Large Vision-Language Model (LVLM) has enhanced the performance of various downstream tasks in visual-language understanding. Most existing approaches encode images and videos into separate feature spaces, which are then fed as inputs…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Bin Lin , Yang Ye , Bin Zhu , Jiaxi Cui , Munan Ning , Peng Jin , Li Yuan

Vision-and-language pretraining (VLP) in the medical field utilizes contrastive learning on image-text pairs to achieve effective transfer across tasks. Yet, current VLP approaches with the masked modeling strategy face two challenges when…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Biao Wu , Yutong Xie , Zeyu Zhang , Minh Hieu Phan , Qi Chen , Ling Chen , Qi Wu

Automated radiology report generation is key for reducing radiologist workload and improving diagnostic consistency, yet generating accurate reports for 3D medical imaging remains challenging. Existing vision-language models face two…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Pengcheng Shi , Minghui Zhang , Kehan Song , Jiaqi Liu , Yun Gu , Xinglin Zhang

The scarcity of well-annotated diverse medical images is a major hurdle for developing reliable AI models in healthcare. Substantial technical advances have been made in generative foundation models for natural images. Here we develop…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Yuanfeng Ji , Dan Lin , Xiyue Wang , Lu Zhang , Wenhui Zhou , Chongjian Ge , Ruihang Chu , Xiaoli Yang , Junhan Zhao , Junsong Chen , Xiangde Luo , Sen Yang , Jin Fang , Ping Luo , Ruijiang Li

This paper explores training medical vision-language models (VLMs) -- where the visual and language inputs are embedded into a common space -- with a particular focus on scenarios where training data is limited, as is often the case in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Rhydian Windsor , Amir Jamaludin , Timor Kadir , Andrew Zisserman

We propose a two-stage multimodal framework that enhances disease classification and region-aware radiology report generation from chest X-rays, leveraging the MIMIC-Eye dataset. In the first stage, we introduce a gaze-guided contrastive…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Tanjim Islam Riju , Shuchismita Anwar , Saman Sarker Joy , Farig Sadeque , Swakkhar Shatabda

Medical Vision-Language Pretraining (MedVLP) shows promise in learning generalizable and transferable visual representations from paired and unpaired medical images and reports. MedVLP can provide useful features to downstream tasks and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Yang Zhou , Tan Li Hui Faith , Yanyu Xu , Sicong Leng , Xinxing Xu , Yong Liu , Rick Siow Mong Goh

In this paper, we present \textbf{Gen}erative \textbf{L}anguage-\textbf{I}mage \textbf{P}re-training (GenLIP), a minimalist generative pretraining framework for Vision Transformers (ViTs) designed for multimodal large language models…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Yan Fang , Mengcheng Lan , Zilong Huang , Weixian Lei , Yunqing Zhao , Yujie Zhong , Yingchen Yu , Qi She , Yao Zhao , Yunchao Wei
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