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Cancer survival prediction is important for developing personalized treatments and inducing disease-causing mechanisms. Multi-omics data integration is attracting widespread interest in cancer research for providing information for…

Genomics · Quantitative Biology 2022-07-12 Xing Wu , Qiulian Fang

Previous studies that used data from Stack Overflow to develop predictive models often employed limited benchmarks of 3-5 models or adopted arbitrary selection methods. Despite being insightful, their limited scope suggests the need to…

Software Engineering · Computer Science 2025-06-24 Elijah Zolduoarrati , Sherlock A. Licorish , Nigel Stanger

The application of machine learning to image and video data often yields a high dimensional feature space. Effective feature selection techniques identify a discriminant feature subspace that lowers computational and modeling costs with…

Machine Learning · Computer Science 2022-06-22 Yijing Yang , Wei Wang , Hongyu Fu , C. -C. Jay Kuo

Identifying co-varying causal elements in very high dimensional feature space with internal structures, e.g., a space with as many as millions of linearly ordered features, as one typically encounters in problems such as whole genome…

Methodology · Statistics 2012-06-18 Seyoung Kim , Eric P. Xing

We present a technique for developing a network of re-used features, where the topology is formed using a coarse learning method, that allows gradient-descent fine tuning, known as an Abstract Deep Network (ADN). New features are built…

Neural and Evolutionary Computing · Computer Science 2014-12-17 Anthony Knittel , Alan Blair

Possessing the five-year durability rate of nearly 5%, currently, the fourth leading cause for cancer-related deaths is pancreatic cancer. Previously, several works have resolved that early diagnosis performs a meaningful function in…

Genomics · Quantitative Biology 2023-06-22 Azmain Yakin Srizon

Clinical risk prediction models often underperform in real-world settings due to poor calibration, limited transportability, and subgroup disparities. These challenges are amplified in high-dimensional multimodal cancer datasets…

Machine Learning · Computer Science 2026-02-26 Toktam Khatibi

Identifying biomarkers in medical images is vital for a wide range of biotech applications. However, recent Transformer and CNN based methods often struggle with variations in morphology and staining, which limits their feature extraction…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Saad Wazir , Daeyoung Kim

Feature selection is a critical step in the analysis of high-dimensional data, where the number of features often vastly exceeds the number of samples. Effective feature selection not only improves model performance and interpretability but…

Machine Learning · Computer Science 2025-01-27 Raquel Espinosa , Gracia Sánchez , José Palma , Fernando Jiménez

Whole genome prediction of complex phenotypic traits using high-density genotyping arrays has attracted a great deal of attention, as it is relevant to the fields of plant and animal breeding and genetic epidemiology. As the number of…

Machine Learning · Computer Science 2013-10-08 Dan He , Irina Rish , David Haws , Simon Teyssedre , Zivan Karaman , Laxmi Parida

Deep-learning-based local feature extraction algorithms that combine detection and description have made significant progress in visible image matching. However, the end-to-end training of such frameworks is notoriously unstable due to the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Yuxin Deng , Jiayi Ma

Prediction of patient survival using high-dimensional multi-omics data requires systematic feature selection methods that ensure predictive performance, sparsity, and reliability for prognostic biomarker discovery. We developed a hybrid…

Genomics · Quantitative Biology 2026-04-15 John Zobolas , Anne-Marie George , Alberto López , Sebastian Fischer , Marc Becker , Tero Aittokallio

BACKGROUND: Breast cancer has emerged as one of the most prevalent cancers among women leading to a high mortality rate. Due to the heterogeneous nature of breast cancer, there is a need to identify differentially expressed genes associated…

Machine Learning · Computer Science 2021-11-30 Sheetal Rajpal , Ankit Rajpal , Manoj Agarwal , Naveen Kumar

Prostate cancer, the second most prevalent male malignancy, requires advanced diagnostic tools. We propose an explainable AI system combining BERT (for textual clinical notes) and Random Forest (for numerical lab data) through a novel…

The choice of crossover and mutation strategies plays a crucial role in the searchability, convergence efficiency and precision of genetic algorithms. In this paper, a novel improved genetic algorithm is proposed by improving the crossover…

Neural and Evolutionary Computing · Computer Science 2022-10-12 Dingming Yang , Zeyu Yu , Hongqiang Yuan , Yanrong Cui

The development of molecular signatures for the prediction of time-to-event outcomes is a methodologically challenging task in bioinformatics and biostatistics. Although there are numerous approaches for the derivation of marker…

Applications · Statistics 2014-01-09 Andreas Mayr , Matthias Schmid

Selecting important features in high-dimensional survival analysis is critical for identifying confirmatory biomarkers while maintaining rigorous error control. In this paper, we propose a derandomized knockoffs procedure for Cox regression…

Methodology · Statistics 2025-12-15 Rui Liu , Nan Sun

Distributed stochastic optimization has drawn great attention recently due to its effectiveness in solving large-scale machine learning problems. Though numerous algorithms have been proposed and successfully applied to general practical…

Optimization and Control · Mathematics 2023-12-15 Kun Huang , Xiao Li , Shi Pu

Background and objective Risk prediction models aim at identifying people at higher risk of developing a target disease. Feature selection is particularly important to improve the prediction model performance avoiding overfitting and to…

Machine Learning · Computer Science 2024-02-09 N. Cueto-López , M. T. García-Ordás , V. Dávila-Batista , V. Moreno , N. Aragonés , R. Alaiz-Rodríguez

Features play an important role in various visual tasks, especially in visual place recognition applied in perceptual changing environments. In this paper, we address the challenges of place recognition due to dynamics and confusable…

Computer Vision and Pattern Recognition · Computer Science 2021-03-23 Yuxin Tian , Jinyu MIao , Xingming Wu , Haosong Yue , Zhong Liu , Weihai Chen