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Histopathological images are the gold standard for diagnosing liver cancer. However, the accuracy of fully digital diagnosis in computational pathology needs to be improved. In this paper, in order to solve the problem of multi-label and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Liangrui Pan , Yutao Dou , Zhichao Feng , Liwen Xu , Shaoliang Peng

Liver cancer is one of the most prevalent and lethal forms of cancer, making early detection crucial for effective treatment. This paper introduces a novel approach for automated liver tumor segmentation in computed tomography (CT) images…

Machine Learning · Computer Science 2025-08-13 Nastaran Ghorbani , Bitasadat Jamshidi , Mohsen Rostamy-Malkhalifeh

Recent advancements in digital pathology have enabled comprehensive analysis of Whole-Slide Images (WSI) from tissue samples, leveraging high-resolution microscopy and computational capabilities. Despite this progress, there is a lack of…

Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam

Liver tumor segmentation plays an important role in hepatocellular carcinoma diagnosis and surgical planning. In this paper, we propose a novel Semantic Feature Attention Network (SFAN) for liver tumor segmentation from Computed Tomography…

Image and Video Processing · Electrical Eng. & Systems 2019-11-04 Yao Zhang , Cheng Zhong , Yang Zhang , Zhongchao Shi , Zhiqiang He

Background: Histopathology is an important modality for the diagnosis and management of many diseases in modern healthcare, and plays a critical role in cancer care. Pathology samples can be large and require multi-site sampling, leading to…

Tissue-level semantic segmentation is a vital step in computational pathology. Fully-supervised models have already achieved outstanding performance with dense pixel-level annotations. However, drawing such labels on the giga-pixel whole…

Image and Video Processing · Electrical Eng. & Systems 2021-10-18 Chu Han , Jiatai Lin , Jinhai Mai , Yi Wang , Qingling Zhang , Bingchao Zhao , Xin Chen , Xipeng Pan , Zhenwei Shi , Xiaowei Xu , Su Yao , Lixu Yan , Huan Lin , Zeyan Xu , Xiaomei Huang , Guoqiang Han , Changhong Liang , Zaiyi Liu

Histology method is vital in the diagnosis and prognosis of cancers and many other diseases. For the analysis of histopathological images, we need to detect and segment all gland structures. These images are very challenging, and the task…

Image and Video Processing · Electrical Eng. & Systems 2019-11-05 Safiye Rezaei , Ali Emami , Nader Karimi , Shadrokh Samavi

Pathologists comprehensive evaluation of donor liver biopsies provides crucial information for accepting or discarding potential grafts. However, rapidly and accurately obtaining these assessments intraoperatively poses a significant…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Liangrui Pan , Xingchen Li , Zhongyi Chen , Ling Chu , Shaoliang Peng

While artificial intelligence (AI) algorithms continue to rival human performance on a variety of clinical tasks, the question of how best to incorporate these algorithms into clinical workflows remains relatively unexplored. We…

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Diagnostic imaging has gained prominence as potential biomarkers for early detection and diagnosis in a diverse array of disorders including cancer. However, existing methods routinely face challenges arising from various factors such as…

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Whole-slide image analysis is essential for diagnostic tasks in pathology, yet existing deep learning methods primarily rely on flat classification, ignoring hierarchical relationships among class labels. In this study, we propose HiClass,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Keunho Byeon , Jinsol Song , Seong Min Hong , Yosep Chong , Jin Tae Kwak

We present an end-to-end deep learning framework for automated liver cirrhosis stage estimation from multi-sequence MRI. Cirrhosis is the severe scarring (fibrosis) of the liver and a common endpoint of various chronic liver diseases. Early…

Definitive cancer diagnosis and management depend upon the extraction of information from microscopy images by pathologists. These images contain complex information requiring time-consuming expert human interpretation that is prone to…

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Neel Kanwal , Roger Amundsen , Helga Hardardottir , Luca Tomasetti , Erling Sandoy Undersrud , Emiel A. M. Janssen , Kjersti Engan

Background & Aims: Hepatic steatosis is a major cause of chronic liver disease. 2D ultrasound is the most widely used non-invasive tool for screening and monitoring, but associated diagnoses are highly subjective. We developed a scalable…

Image and Video Processing · Electrical Eng. & Systems 2021-10-13 Bowen Li , Dar-In Tai , Ke Yan , Yi-Cheng Chen , Shiu-Feng Huang , Tse-Hwa Hsu , Wan-Ting Yu , Jing Xiao , Le Lu , Adam P. Harrison

Liver fibrosis represents a significant global health burden, necessitating accurate staging for effective clinical management. This report introduces the LiQA (Liver Fibrosis Quantification and Analysis) dataset, established as part of the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Yuanye Liu , Hanxiao Zhang , Jiyao Liu , Nannan Shi , Yuxin Shi , Arif Mahmood , Murtaza Taj , Xiahai Zhuang
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