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Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and the most common cause of death of people suffering from cirrhosis. The segmentation of liver lesions in CT images allows assessment of tumor load,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Nadja Gruber , Stephan Antholzer , Werner Jaschke , Christian Kremser , Markus Haltmeier

Histopathology remains the gold standard for diagnosis of various cancers. Recent advances in computer vision, specifically deep learning, have facilitated the analysis of histopathology images for various tasks, including immune cell…

Quantitative Methods · Quantitative Biology 2023-11-02 Jakub R. Kaczmarzyk , Tahsin M. Kurc , Shahira Abousamra , Rajarsi Gupta , Joel H. Saltz , Peter K. Koo

Non-invasive radiological-based lesion characterization and identification, e.g., to differentiate cancer subtypes, has long been a major aim to enhance oncological diagnosis and treatment procedures. Here we study a specific population of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-01 Yuankai Huo , Jinzheng Cai , Chi-Tung Cheng , Ashwin Raju , Ke Yan , Bennett A. Landman , Jing Xiao , Le Lu , Chien-Hung Liao , Adam P. Harrison

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Colorectal liver metastasis is one of most aggressive liver malignancies. While the definition of lesion type based on CT images determines the diagnosis and therapeutic strategy, the discrimination between cancerous and non-cancerous…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Francisco Perdigon Romero , Andre Diler , Gabriel Bisson-Gregoire , Simon Turcotte , Real Lapointe , Franck Vandenbroucke-Menu , An Tang , Samuel Kadoury

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Hepatocellular Carcinoma diagnosis relies heavily on the interpretation of gigapixel Whole Slide Images. However, current computational approaches are constrained by fixed-resolution processing mechanisms and inefficient feature…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yuxuan Yang , Zhonghao Yan , Yi Zhang , Bo Yun , Muxi Diao , Guowei Zhao , Kongming Liang , Wenbin Li , Zhanyu Ma

We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Abhijeet Patil , Garima Jain , Harsh Diwakar , Jay Sawant , Tripti Bameta , Swapnil Rane , Amit Sethi

Liver cancer has high morbidity and mortality rates in the world. Multi-phase CT is a main medical imaging modality for detecting/identifying and diagnosing liver tumors. Automatically detecting and classifying liver lesions in CT images…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Fakai Wang , Chi-Tung Cheng , Chien-Wei Peng , Ke Yan , Min Wu , Le Lu , Chien-Hung Liao , Ling Zhang

Microscopic examination of slides prepared from tissue samples is the primary tool for detecting and classifying cancerous lesions, a process that is time-consuming and requires the expertise of experienced pathologists. Recent advances in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Saba Fatema , Brighton Nuwagira , Sayoni Chakraborty , Reyhan Gedik , Baris Coskunuzer

The diagnosis of primary liver cancers (PLCs) can be challenging, especially on biopsies and for combined hepatocellular-cholangiocarcinoma (cHCC-CCA). We automatically classified PLCs on routine-stained biopsies using a weakly supervised…

Renal cell carcinoma (RCC) is the most common renal cancer in adults. The histopathologic classification of RCC is essential for diagnosis, prognosis, and management of patients. Reorganization and classification of complex histologic…

Image and Video Processing · Electrical Eng. & Systems 2020-11-02 Mengdan Zhu , Bing Ren , Ryland Richards , Matthew Suriawinata , Naofumi Tomita , Saeed Hassanpour

Breast cancer has the highest mortality among cancers in women. Computer-aided pathology to analyze microscopic histopathology images for diagnosis with an increasing number of breast cancer patients can bring the cost and delays of…

Computer Vision and Pattern Recognition · Computer Science 2020-03-03 Abhijeet Patil , Dipesh Tamboli , Swati Meena , Deepak Anand , Amit Sethi

Liver cancer has a high incidence rate, but primary healthcare settings often lack experienced doctors. Advances in large models and AI technologies offer potential assistance. This work aims to address limitations in liver cancer diagnosis…

Medical Physics · Physics 2024-06-27 Xuzhou Wu , Guangxin Li , Xing Wang , Zeyu Xu , Yingni Wang , Jianming Xian , Xueyu Wang , Gong Li , Kehong Yuan

Background: Liver cancer ranks as the fifth most common malignant tumor and the second most fatal in our country. Early diagnosis is crucial, necessitating that physicians identify liver cancer in patients at the earliest possible stage.…

Information Retrieval · Computer Science 2024-10-25 YiChi Zhang , HaiLing Wang , YongBin Gao , XiaoJun Hu , YingFang Fan , ZhiJun Fang

We propose a fully-automated method for accurate and robust detection and segmentation of potentially cancerous lesions found in the liver and in lymph nodes. The process is performed in three steps, including organ detection, lesion…

Computer Vision and Pattern Recognition · Computer Science 2017-03-21 Assaf Hoogi , John W. Lambert , Yefeng Zheng , Dorin Comaniciu , Daniel L. Rubin

Using radiological scans to identify liver tumors is crucial for proper patient treatment. This is highly challenging, as top radiologists only achieve F1 scores of roughly 80% (hepatocellular carcinoma (HCC) vs. others) with only moderate…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Bolin Lai , Yuhsuan Wu , Xiaoyu Bai , Xiao-Yun Zhou , Peng Wang , Jinzheng Cai , Yuankai Huo , Lingyun Huang , Yong Xia , Jing Xiao , Le Lu , Heping Hu , Adam Harrison

Pediatric liver tumors are one of the most common solid tumors in pediatrics, with differentiation of benign or malignant status and pathological classification critical for clinical treatment. While pathological examination is the gold…

Image and Video Processing · Electrical Eng. & Systems 2026-01-29 Wanqi Wang , Chun Yang , Jianbo Shao , Yaokai Zhang , Xuehua Peng , Jin Sun , Chao Xiong , Long Lu , Lianting Hu

Cancer is one of the most common and fatal diseases in the world. Breast cancer affects one in every eight women and one in every eight hundred men. Hence, our prime target should be early detection of cancer because the early detection of…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Jitendra Maan , Harsh Maan

The microvascular invasion (MVI) is a major prognostic factor in hepatocellular carcinoma, which is one of the malignant tumors with the highest mortality rate. The diagnosis of MVI needs discovering the vessels that contain hepatocellular…

Computer Vision and Pattern Recognition · Computer Science 2021-08-03 Zunlei Feng , Zhonghua Wang , Xinchao Wang , Xiuming Zhang , Lechao Cheng , Jie Lei , Yuexuan Wang , Mingli Song