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Recently, it has become progressively more evident that classic diagnostic labels are unable to reliably describe the complexity and variability of several clinical phenotypes. This is particularly true for a broad range of neuropsychiatric…

Machine Learning · Computer Science 2024-02-28 Giovanna Maria Dimitri , Simeon Spasov , Andrea Duggento , Luca Passamonti , Pietro Li`o , Nicola Toschi

Hypergraphs are generalisation of graphs in which a hyperedge can connect any number of vertices. It can describe n-ary relationships and high-order information among entities compared to conventional graphs. In this paper, we study the…

Databases · Computer Science 2023-02-21 Zhengyi Yang , Wenjie Zhang , Xuemin Lin , Ying Zhang , Shunyang Li

Graph neural networks (GNNs) have demonstrated promising performance across various chemistry-related tasks. However, conventional graphs only model the pairwise connectivity in molecules, failing to adequately represent higher-order…

Chemical Physics · Physics 2023-12-22 Junwu Chen , Philippe Schwaller

We study the implications of the modeling choice to use a graph, instead of a hypergraph, to represent real-world interconnected systems whose constituent relationships are of higher order by nature. Such a modeling choice typically…

Machine Learning · Computer Science 2024-01-17 Yanbang Wang , Jon Kleinberg

The rapid advancement of medical technology has led to an exponential increase in multi-modal medical data, including imaging, genomics, and electronic health records (EHRs). Graph neural networks (GNNs) have been widely used to represent…

Quantitative Methods · Quantitative Biology 2024-10-03 Favour Nerrise , Alice Louise Heiman , Ehsan Adeli

Hypergraph can capture complex and higher-order dependencies among learners and learning resources in personalized educational recommender systems. Many existing hypergraph-based recommendation approaches underexplored the dynamic…

Information Retrieval · Computer Science 2026-03-17 Tao Xie , Yan Li , Yongpan Sheng , Jian Liao

One of the aims of systems biology is to build multiple layered and multiple scale models of living systems which can efficiently describe phenomena occurring at various level of resolution. Such models should consist of layers of various…

Dynamical Systems · Mathematics 2015-03-03 Jacek Banasiak , Aleksandra Falkiewicz , Proscovia Namayanja

Recurrent Neural Network models have elucidated the interplay between structure and dynamics in biological neural networks, particularly the emergence of irregular and rhythmic activities in cortex. However, most studies have focused on…

Neurons and Cognition · Quantitative Biology 2025-09-04 Nimrod Sherf , Xaq Pitkow , Krešimir Josić , Kevin E. Bassler

The availability of network datasets advances research in network science, machine learning and related fields by enabling empirical analyses and their reproducibility, algorithm development, model validation and benchmarking. Existing…

Sensor networks increasingly govern modern infrastructure, yet the data they lose are rarely missing in the uniform-random patterns assumed by standard imputation benchmarks. Loop detectors go offline during calibration, roadside cabinets…

Machine Learning · Computer Science 2026-05-19 Keshu Wu , Sixu Li , Zihao Li , Zhiwen Fan , Xiaopeng Li , Yang Zhou

Many networked systems are governed by non-pairwise interactions between nodes. The resulting higher-order interaction structure can then be encoded by means of a hypernetwork. In this paper we consider dynamical systems on hypernetworks by…

Dynamical Systems · Mathematics 2023-08-11 Sören von der Gracht , Eddie Nijholt , Bob Rink

Many supervised machine learning frameworks have been proposed for disease classification using functional magnetic resonance imaging (fMRI) data, producing important biomarkers. More recently, data pooling has flourished, making the result…

Quantitative Methods · Quantitative Biology 2022-02-24 Dushyant Sahoo , Mathilde Antoniades , Cynthia H. Y. Fu , Christos Davatzikos

Multiplex networks describe a large number of systems ranging from social networks to the brain. These multilayer structure encode information in their structure. This information can be extracted by measuring the correlations present in…

Disordered Systems and Neural Networks · Physics 2015-04-23 Giulia Menichetti , Daniel Remondini , Ginestra Bianconi

We analyze networked heterogeneous nonlinear systems, with diffusive coupling and interconnected over a generic static directed graph. Due to the network's hetereogeneity, complete synchronization is impossible, in general, but an emergent…

Optimization and Control · Mathematics 2022-06-01 Mohamed Maghenem , Elena Panteley , Antonio Loria

Groups with complex set intersection relations are a natural way to model a wide array of data, from the formation of social groups to the complex protein interactions which form the basis of biological life. One approach to representing…

Machine Learning · Computer Science 2025-01-15 Sepideh Maleki , Josh Vekhter , Keshav Pingali

Quantifying which neurons are important with respect to the classification decision of a trained neural network is essential for understanding their inner workings. Previous work primarily attributed importance to individual neurons. In…

Machine Learning · Computer Science 2022-11-09 Kenzo Clauw , Sebastiano Stramaglia , Daniele Marinazzo

Higher-order interactions have recently emerged as a promising framework for describing new dynamical phenomena in heterogeneous contagion processes. However, a fundamental open question is how to understand their contribution from the…

Statistical Mechanics · Physics 2026-05-21 Sandro Meloni , Andrea Gabrielli , Pablo Villegas

Non-dyadic higher-order interactions affect collective behavior in various networked dynamical systems. Here we discuss the properties of a novel Ising model with higher-order interactions and characterize its phase transitions between the…

Statistical Mechanics · Physics 2024-12-02 Thomas Robiglio , Leonardo Di Gaetano , Ada Altieri , Giovanni Petri , Federico Battiston

Networks involved in information processing often have their nodes arranged hierarchically, with the majority of connections occurring in adjacent levels. However, despite being an intuitively appealing concept, the hierarchical…

Neurons and Cognition · Quantitative Biology 2024-07-02 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

Many real-world complex systems are characterized by non-pairwise -- higher-order -- interactions among system's units, and can be effectively modeled as hypergraphs. Directed hypergraphs distinguish between source and target sets within…

Physics and Society · Physics 2025-12-17 Quintino Francesco Lotito , Alberto Vendramini , Alberto Montresor , Federico Battiston