English
Related papers

Related papers: Optimal Stopping in Sequential Clinical Prediction

200 papers

Selective labels are a common feature of consequential decision-making applications, referring to the lack of observed outcomes under one of the possible decisions. This paper reports work in progress on learning decision policies in the…

Machine Learning · Computer Science 2020-11-04 Dennis Wei

In most prediction and estimation situations, scientists consider various statistical models for the same problem, and naturally want to select amongst the best. Hansen et al. (2011) provide a powerful solution to this problem by the…

Methodology · Statistics 2026-01-23 Sebastian Arnold , Georgios Gavrilopoulos , Benedikt Schulz , Johanna Ziegel

Suppose that at any stage of a statistical experiment a control variable $X$ that affects the distribution of the observed data $Y$ can be used. The distribution of $Y$ depends on some unknown parameter $\theta$, and we consider the…

Statistics Theory · Mathematics 2010-05-05 Andrey Novikov

Our research is closely related to ontological studies in mathematics. It provides crucial insights into the nature of decisions and strategies characterized by Markov moments. In a stopping game, a holistic decision-maker would evaluate…

Optimization and Control · Mathematics 2026-04-29 Georgy Sofronov , Joanna Rymaszewska , Krzysztof J. Szajowski

Most decision-focused learning work has focused on single stage problems whereas many real-world decision problems are more appropriately modelled using multistage optimisation. In multistage problems contextual information is revealed over…

Optimization and Control · Mathematics 2025-05-29 Egon Peršak , Miguel F. Anjos

Decision-making problems often feature uncertainty stemming from heterogeneous and context-dependent human preferences. To address this, we propose a sequential learning-and-optimization pipeline to learn preference distributions and…

Machine Learning · Computer Science 2026-03-19 Benjamin Hudson , Laurent Charlin , Emma Frejinger

Adaptive designs have been proposed for clinical trials in which the nuisance parameters or alternative of interest are unknown or likely to be misspecified before the trial. Whereas most previous works on adaptive designs and mid-course…

Methodology · Statistics 2011-05-18 Jay Bartroff , Tze Leung Lai

Many medical decision-making tasks can be framed as partially observed Markov decision processes (POMDPs). However, prevailing two-stage approaches that first learn a POMDP and then solve it often fail because the model that best fits the…

Machine Learning · Statistics 2020-04-01 Joseph Futoma , Michael C. Hughes , Finale Doshi-Velez

The task of learning to pick a single preferred example out a finite set of examples, an "optimal choice problem", is a supervised machine learning problem with complex, structured input. Problems of optimal choice emerge often in various…

Artificial Intelligence · Computer Science 2017-07-07 Marina Sapir

Major postoperative complications are devastating to surgical patients. Some of these complications are potentially preventable via early predictions based on intraoperative data. However, intraoperative data comprise long and fine-grained…

Machine Learning · Computer Science 2022-10-11 Dingwen Li , Bing Xue , Christopher King , Bradley Fritz , Michael Avidan , Joanna Abraham , Chenyang Lu

This research addresses the challenge of conducting interpretable causal inference between a binary treatment and its resulting outcome when not all confounders are known. Confounders are factors that have an influence on both the treatment…

Machine Learning · Computer Science 2023-10-24 Sohaib Kiani , Jared Barton , Jon Sushinsky , Lynda Heimbach , Bo Luo

We consider conditions that allow us to find an optimal strategy for sequential decisions from a given data situation. For the case where all interventions are unconditional (atomic), identifiability has been discussed by Pearl & Robins…

Artificial Intelligence · Computer Science 2020-04-28 Philip Dawid , Vanessa Didelez

Checklists are simple decision aids that are often used to promote safety and reliability in clinical applications. In this paper, we present a method to learn checklists for clinical decision support. We represent predictive checklists as…

Machine Learning · Computer Science 2022-01-19 Haoran Zhang , Quaid Morris , Berk Ustun , Marzyeh Ghassemi

We study the sequential batch learning problem in linear contextual bandits with finite action sets, where the decision maker is constrained to split incoming individuals into (at most) a fixed number of batches and can only observe…

Machine Learning · Computer Science 2020-04-15 Yanjun Han , Zhengqing Zhou , Zhengyuan Zhou , Jose Blanchet , Peter W. Glynn , Yinyu Ye

Feature selection is an important problem in machine learning, which aims to select variables that lead to an optimal predictive model. In this paper, we focus on feature selection for post-intervention outcome prediction from…

Machine Learning · Statistics 2021-03-16 Sofia Triantafillou , Fattaneh Jabbari , Greg Cooper

Large reasoning models rely on long chain-of-thought generation to solve complex problems, but extended reasoning often incurs substantial computational cost and can even degrade performance due to overthinking. A key challenge is…

Computation and Language · Computer Science 2026-04-07 Parsa Hosseini , Sumit Nawathe , Mahdi Salmani , Meisam Razaviyayn , Soheil Feizi

We consider the problem of choosing the optimal (in the sense of mean-squared prediction error) multistep predictor for an autoregressive (AR) process of finite but unknown order. If a working AR model (which is possibly misspecified) is…

Statistics Theory · Mathematics 2007-06-13 Ching-Kang Ing

This paper explores continuous-time and state-space optimal stopping problems from a reinforcement learning perspective. We begin by formulating the stopping problem using randomized stopping times, where the decision maker's control is…

Optimization and Control · Mathematics 2026-03-12 Jodi Dianetti , Giorgio Ferrari , Renyuan Xu

Modern sequential recommender systems, ranging from lightweight transformer-based variants to large language models, have become increasingly prominent in academia and industry due to their strong performance in the next-item prediction…

Information Retrieval · Computer Science 2025-08-11 Danil Gusak , Anna Volodkevich , Anton Klenitskiy , Alexey Vasilev , Evgeny Frolov

Active learning allows machine learning models to be trained using fewer labels while retaining similar performance to traditional supervised learning. An active learner selects the most informative data points, requests their labels, and…

Machine Learning · Computer Science 2023-11-22 Zac Pullar-Strecker , Katharina Dost , Eibe Frank , Jörg Wicker