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The versatility of large language models (LLMs) has been explored across various sectors, but their application in healthcare poses challenges, particularly in the domain of pharmaceutical contraindications where accurate and reliable…

Artificial Intelligence · Computer Science 2025-08-11 Byeonghun Bang , Jongsuk Yoon , Dong-Jin Chang , Seho Park , Yong Oh Lee

We propose an adaptive sampling approach for multiple testing which aims to maximize statistical power while ensuring anytime false discovery control. We consider $n$ distributions whose means are partitioned by whether they are below or…

Machine Learning · Statistics 2019-07-18 Kevin Jamieson , Lalit Jain

Multi-step LLM pipelines can solve complex tasks, but jointly optimizing prompts across steps remains challenging due to missing step-level supervision and inter-step dependency. We propose ADOPT, an adaptive dependency-guided joint prompt…

Computation and Language · Computer Science 2026-04-09 Minjun Zhao , Xinyu Zhang , Shuai Zhang , Deyang Li , Ruifeng Shi

Recent mechanistic studies suggest that large language models (LLMs) may utilize their depth inefficiently in standard single-turn tasks. Whether this still holds in autonomous agent settings, where models must perform multi-turn planning,…

Artificial Intelligence · Computer Science 2026-05-28 Zhenyu Cui , Xiangzhong Luo

Psychological measurement is essential for mental health, self-understanding, and personal development. Traditional methods, such as self-report scales and psychologist interviews, often face challenges with engagement and accessibility.…

Computation and Language · Computer Science 2024-08-30 Qisen Yang , Zekun Wang , Honghui Chen , Shenzhi Wang , Yifan Pu , Xin Gao , Wenhao Huang , Shiji Song , Gao Huang

Large language models (LLMs) are increasingly utilized in clinical reasoning and risk assessment. However, their interpretive reliability in critical and indeterminate domains such as psychiatry remains unclear. Prior work has identified…

Machine Learning · Computer Science 2026-04-30 Shevya Panda , Shinjini Bose , Ananya Joshi

Automated evidence-based misinformation detection systems, which evaluate the veracity of short claims against evidence, lack comprehensive analysis of their adversarial vulnerabilities. Existing black-box text-based adversarial attacks are…

Computation and Language · Computer Science 2025-05-06 Mazal Bethany , Nishant Vishwamitra , Cho-Yu Jason Chiang , Peyman Najafirad

We study the automated derivation of safety requirements in a self-driving vehicle use case, leveraging LLMs in combination with agent-based retrieval-augmented generation. Conventional approaches that utilise pre-trained LLMs to assist in…

Artificial Intelligence · Computer Science 2025-04-16 Balahari Vignesh Balu , Florian Geissler , Francesco Carella , Joao-Vitor Zacchi , Josef Jiru , Nuria Mata , Reinhard Stolle

Large Language Model (LLM)-based Multi-Agent Systems (MAS) enable complex problem-solving but introduce significant debugging challenges, characterized by long interaction traces, inter-agent dependencies, and delayed error manifestation.…

Multiagent Systems · Computer Science 2026-04-21 Jiazheng Li , Emine Yilmaz , Bei Chen , Dieu-Thu Le

Automatic Prompt Optimization (APO) has emerged as a critical technique for enhancing Large Language Model (LLM) performance, yet current state-of-the-art methods typically rely on large, labeled gold-standard development sets to compute…

Automatic Short Answer Grading (ASAG) with generative large language models (LLMs) has recently demonstrated strong performance without task-specific fine-tuning, while also enabling the generation of synthetic feedback for educational…

Computation and Language · Computer Science 2026-05-14 Longwei Cong , Sonja Hahn , Sebastian Gombert , Leon Camus , Hendrik Drachsler , Ulf Kroehne

Suicide prediction is the key for prevention, but real data with sufficient positive samples is rare and causes extreme class imbalance. We utilized machine learning (ML) to build the model and deep learning (DL) techniques, like Generative…

Machine Learning · Computer Science 2025-10-21 Vaishnavi Visweswaraiah , Tanvi Banerjee , William Romine

Multi-agent LLM systems introduce a security risk in which sensitive information accessed by one agent can propagate through shared context and reappear in downstream outputs, even without explicit adversarial intent. We formalise this…

Artificial Intelligence · Computer Science 2026-05-12 Riya Tapwal , Abhishek Kumar , Carsten Maple

Large Language Models (LLMs) are increasingly integrated into critical decision-making pipelines, a trend that raises the demand for robust and automated data analysis. Current approaches to dataset risk analysis are limited to manual…

Artificial Intelligence · Computer Science 2026-05-28 Panteleimon Rodis

While Multi-Agent Systems (MAS) excel in complex reasoning, they suffer from the cascading impact of erroneous information from individual agents. Current solutions often resort to rigid structural engineering or expensive fine-tuning,…

Artificial Intelligence · Computer Science 2026-05-29 Yutong Wang , Siyuan Xiong , Xuebo Liu , Wenkang Zhou , Liang Ding , Miao Zhang , Min Zhang

Multiple myeloma is managed through sequential lines of therapy over years to decades, with each decision depending on cumulative disease history distributed across dozens to hundreds of heterogeneous clinical documents. Whether LLM-based…

As an extension of the classical multi-armed bandit problem, multi-fidelity multi-armed bandits (MF-MAB) enable individual arms to be evaluated using diverse feedback sources that vary in both cost and accuracy. Prior stochastic models…

Machine Learning · Computer Science 2026-05-12 Muyun Lu , Haoyang Hong , Huazheng Wang , Ying Lin

The integration of experimental technologies with large language models (LLMs) is transforming scientific research. It positions AI as a versatile research assistant rather than a mere problem-solving tool. In the field of power systems,…

Computation and Language · Computer Science 2025-05-20 Mengshuo Jia , Zeyu Cui , Gabriela Hug

Ecological Momentary Assessment provides real-time data on suicidal thoughts and behaviors, but predicting suicide attempts remains challenging due to their rarity and patient heterogeneity. We show that single models fit to all patients…

Machine Learning · Statistics 2025-11-25 Genesis Hang , Annie Chen , Hope Neveux , Matthew K. Nock , Yaniv Yacoby

Systematic exploration of Agent-Based Models (ABMs) is challenged by the curse of dimensionality and their inherent stochasticity. We present a multi-stage pipeline integrating the systematic design of experiments with machine learning…

Machine Learning · Computer Science 2026-04-07 Paul Saves , Matthieu Mastio , Nicolas Verstaevel , Benoit Gaudou
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