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The scientific claims drawn from LLM social simulations should be no stronger than the robustness audits that support them. Generative agents bring new expressive power to agent-based modeling, enabling simulations of collective social…

Physics and Society · Physics 2026-05-20 Jinyi Ye , Lei Cao , Ding Chen , Emilio Ferrara

Fully automated self-driving laboratories are promising to enable high-throughput and large-scale scientific discovery by reducing repetitive labour. However, effective automation requires deep integration of laboratory knowledge, which is…

Artificial Intelligence · Computer Science 2025-09-30 Shuxiang Cao , Zijian Zhang , Mohammed Alghadeer , Simone D Fasciati , Michele Piscitelli , Mustafa Bakr , Peter Leek , Alán Aspuru-Guzik

Automatic fact-checking aims to support professional fact-checkers by offering tools that can help speed up manual fact-checking. Yet, existing frameworks fail to address the key step of producing output suitable for broader dissemination…

Large Language Models (LLMs) offer a promising basis for creating agents that can tackle complex tasks through iterative environmental interaction. Existing methods either require these agents to mimic expert-provided trajectories or rely…

Computation and Language · Computer Science 2024-12-02 Dihong Gong , Pu Lu , Zelong Wang , Meng Zhou , Xiuqiang He

AI holds promise for transforming scientific processes, including hypothesis generation. Prior work on hypothesis generation can be broadly categorized into theory-driven and data-driven approaches. While both have proven effective in…

Artificial Intelligence · Computer Science 2025-01-10 Haokun Liu , Yangqiaoyu Zhou , Mingxuan Li , Chenfei Yuan , Chenhao Tan

Advances in large language models (LLMs) are rapidly transforming scientific work, yet empirical evidence on how these systems reshape research activities remains limited. We report a mixed-methods pilot evaluation of an AI-orchestrated…

Computers and Society · Computer Science 2026-02-24 Yuan An

Scientific publishing systematically filters out negative results. We argue that this long-standing asymmetry has become an urgent problem in the era of large language models, which inherit the positive bias of the literature they are…

Digital Libraries · Computer Science 2026-04-09 Sungmin Lee

Foundation models are increasingly used in scientific research, but evaluating AI-generated scientific work remains challenging. While expert reviews are costly, large language models (LLMs) as proxy reviewers have proven to be unreliable.…

Computers and Society · Computer Science 2025-03-11 Niklas Höpner , Leon Eshuijs , Dimitrios Alivanistos , Giacomo Zamprogno , Ilaria Tiddi

Scientific Large Language Models (Sci-LLMs) are transforming how knowledge is represented, integrated, and applied in scientific research, yet their progress is shaped by the complex nature of scientific data. This survey presents a…

Computation and Language · Computer Science 2025-10-21 Ming Hu , Chenglong Ma , Wei Li , Wanghan Xu , Jiamin Wu , Jucheng Hu , Tianbin Li , Guohang Zhuang , Jiaqi Liu , Yingzhou Lu , Ying Chen , Chaoyang Zhang , Cheng Tan , Jie Ying , Guocheng Wu , Shujian Gao , Pengcheng Chen , Jiashi Lin , Haitao Wu , Lulu Chen , Fengxiang Wang , Yuanyuan Zhang , Xiangyu Zhao , Feilong Tang , Encheng Su , Junzhi Ning , Xinyao Liu , Ye Du , Changkai Ji , Pengfei Jiang , Cheng Tang , Ziyan Huang , Jiyao Liu , Jiaqi Wei , Yuejin Yang , Xiang Zhang , Guangshuai Wang , Yue Yang , Huihui Xu , Ziyang Chen , Yizhou Wang , Chen Tang , Jianyu Wu , Yuchen Ren , Siyuan Yan , Zhonghua Wang , Zhongxing Xu , Shiyan Su , Shangquan Sun , Runkai Zhao , Zhisheng Zhang , Dingkang Yang , Jinjie Wei , Jiaqi Wang , Jiahao Xu , Jiangtao Yan , Wenhao Tang , Hongze Zhu , Yu Liu , Fudi Wang , Yiqing Shen , Yuanfeng Ji , Yanzhou Su , Tong Xie , Hongming Shan , Chun-Mei Feng , Zhi Hou , Diping Song , Lihao Liu , Yanyan Huang , Lequan Yu , Bin Fu , Shujun Wang , Xiaomeng Li , Xiaowei Hu , Yun Gu , Ben Fei , Benyou Wang , Yuewen Cao , Minjie Shen , Jie Xu , Haodong Duan , Fang Yan , Hongxia Hao , Jielan Li , Jiajun Du , Yanbo Wang , Imran Razzak , Zhongying Deng , Chi Zhang , Lijun Wu , Conghui He , Zhaohui Lu , Jinhai Huang , Wenqi Shao , Yihao Liu , Siqi Luo , Yi Xin , Xiaohong Liu , Fenghua Ling , Yuqiang Li , Aoran Wang , Siqi Sun , Qihao Zheng , Nanqing Dong , Tianfan Fu , Dongzhan Zhou , Yan Lu , Wenlong Zhang , Jin Ye , Jianfei Cai , Yirong Chen , Wanli Ouyang , Yu Qiao , Zongyuan Ge , Shixiang Tang , Junjun He , Chunfeng Song , Lei Bai , Bowen Zhou

With ChatGPT-like large language models (LLM) prevailing in the community, how to evaluate the ability of LLMs is an open question. Existing evaluation methods suffer from following shortcomings: (1) constrained evaluation abilities, (2)…

Artificial Intelligence · Computer Science 2023-08-09 Jiaju Lin , Haoran Zhao , Aochi Zhang , Yiting Wu , Huqiuyue Ping , Qin Chen

Successful agent-human partnerships require that any agent generated information is understandable to the human, and that the human can easily steer the agent towards a goal. Such effective communication requires the agent to develop a…

Human-Computer Interaction · Computer Science 2025-04-24 Vikas Kushwaha , Sruti Srinivasa Ragavan , Subhajit Roy

Simulating consumer decision-making is vital for designing and evaluating marketing strategies before costly real-world deployment. However, post-event analyses and rule-based agent-based models (ABMs) struggle to capture the complexity of…

Artificial Intelligence · Computer Science 2025-10-22 Man-Lin Chu , Lucian Terhorst , Kadin Reed , Tom Ni , Weiwei Chen , Rongyu Lin

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Large language models (LLMs) have been touted to enable increased productivity in many areas of today's work life. Scientific research as an area of work is no exception: the potential of LLM-based tools to assist in the daily work of…

Software Engineering · Computer Science 2024-04-24 Mohamed Nejjar , Luca Zacharias , Fabian Stiehle , Ingo Weber

Explanations for AI models in high-stakes domains like medicine often lack verifiability, which can hinder trust. To address this, we propose an interactive agent that produces explanations through an auditable sequence of actions. The…

Artificial Intelligence · Computer Science 2025-11-04 Yuhang Huang , Zekai Lin , Fan Zhong , Lei Liu

Recently, Large Language Models (LLMs) have been applied to scientific equation discovery, leveraging their embedded scientific knowledge for hypothesis generation. However, current methods typically confine LLMs to the role of an equation…

Artificial Intelligence · Computer Science 2026-02-18 Shijie Xia , Yuhan Sun , Pengfei Liu

Large language models (LLMs) offer significant promise as a knowledge source for task learning. Prompt engineering has been shown to be effective for eliciting knowledge from an LLM, but alone it is insufficient for acquiring relevant,…

Artificial Intelligence · Computer Science 2024-02-21 James R. Kirk , Robert E. Wray , Peter Lindes , John E. Laird

This article discusses the challenges of testing software systems with increasingly integrated AI and LLM functionalities. LLMs are powerful but unreliable, and labeled ground truth for testing rarely scales. Metamorphic Testing solves this…

Software Engineering · Computer Science 2026-03-27 Valerio Terragni

As the development of AI-generated contents (AIGC), multi-modal Large Language Models (LLM) struggle to identify generated visual inputs from real ones. Such shortcoming causes vulnerability against visual deceptions, where the models are…

Artificial Intelligence · Computer Science 2025-11-25 Yinjie Zhao , Heng Zhao , Bihan Wen , Joey Tianyi Zhou

Data-driven scientific discovery requires the iterative integration of scientific domain knowledge, statistical expertise, and an understanding of data semantics to make nuanced analytical decisions, e.g., about which variables,…