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Retrieving information from EHR systems is essential for answering specific questions about patient journeys and improving the delivery of clinical care. Despite this fact, most EHR systems still rely on keyword-based searches. With the…

Computation and Language · Computer Science 2024-04-11 Shashi Kant Gupta , Aditya Basu , Bradley Taylor , Anai Kothari , Hrituraj Singh

In the fast-evolving field of information retrieval (IR), the integration of generative AI technologies such as large language models (LLMs) is transforming how users search for and interact with information. Recognizing this paradigm shift…

Information Retrieval · Computer Science 2024-12-04 James Allan , Eunsol Choi , Daniel P. Lopresti , Hamed Zamani

Patient-generated health data (PGHD) allows healthcare professionals to have a holistic and objective view of their patients. However, its integration in cardiac risk reduction remains unexplored. Through co-design with experienced…

Human-Computer Interaction · Computer Science 2025-11-04 Pavithren V S Pakianathan , Rania Islambouli , Hannah McGowan , Diogo Branco , Tiago Guerreiro , Jan David Smeddinck

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

Computation and Language · Computer Science 2024-12-03 Zifeng Wang , Hanyin Wang , Benjamin Danek , Ying Li , Christina Mack , Hoifung Poon , Yajuan Wang , Pranav Rajpurkar , Jimeng Sun

Electronic Health Records (EHRs), comprising diverse clinical data such as diagnoses, medications, and laboratory results, hold great promise for translational research. EHR-derived data have advanced disease prevention, improved clinical…

Machine Learning · Statistics 2025-09-09 Yinjie Wang , Doudou Zhou , Yue Liu , Junwei Lu , Tianxi Cai

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Improving large language models (LLMs) for electronic health record (EHR) reasoning is essential for enabling accurate and generalizable clinical predictions. While LLMs excel at medical text understanding, they underperform on EHR-based…

Artificial Intelligence · Computer Science 2025-08-20 Yue Fang , Yuxin Guo , Jiaran Gao , Hongxin Ding , Xinke Jiang , Weibin Liao , Yongxin Xu , Yinghao Zhu , Zhibang Yang , Liantao Ma , Junfeng Zhao , Yasha Wang

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

Objective: This article offers a taxonomy of generative artificial intelligence (AI) for health economics and outcomes research (HEOR), explores its emerging applications, and outlines methods to enhance the accuracy and reliability of…

Machine Learning · Computer Science 2025-06-02 Rachael Fleurence , Xiaoyan Wang , Jiang Bian , Mitchell K. Higashi , Turgay Ayer , Hua Xu , Dalia Dawoud , Jagpreet Chhatwal

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

The advances and availability of technologies involving Generative Artificial Intelligence (AI) are evolving clearly and explicitly, driving immediate changes in various work activities. Software Engineering (SE) is no exception and stands…

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Generative AI has demonstrated strong potential in healthcare, from clinical decision support to patient-facing chatbots that improve outcomes. A critical challenge for deployment is effective human-AI communication, where content must be…

Computation and Language · Computer Science 2025-07-11 Hieu Tran , Zonghai Yao , Won Seok Jang , Sharmin Sultana , Allen Chang , Yuan Zhang , Hong Yu

Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

Large language models (LLMs) hold promise for transforming healthcare, from streamlining administrative and clinical workflows to enriching patient engagement and advancing clinical decision-making. However, their successful integration…

Computers and Society · Computer Science 2025-04-04 Mohammed Al-Garadi , Tushar Mungle , Abdulaziz Ahmed , Abeed Sarker , Zhuqi Miao , Michael E. Matheny

Human-AI collaborative tools attract attentions from the data storytelling community to lower the expertise barrier and streamline the workflow. The recent advance in large-scale generative AI techniques, e.g., large language models (LLMs)…

Human-Computer Interaction · Computer Science 2025-10-31 Haotian Li , Yun Wang , Huamin Qu

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

Machine learning provides many powerful and effective techniques for analysing heterogeneous electronic health records (EHR). Administrative Health Records (AHR) are a subset of EHR collected for administrative purposes, and the use of…

Machine Learning · Computer Science 2023-08-29 Adrian Caruana , Madhushi Bandara , Katarzyna Musial , Daniel Catchpoole , Paul J. Kennedy

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

Large Language Models (LLMs) have become a key topic in AI and NLP, transforming sectors like healthcare, finance, education, and marketing by improving customer service, automating tasks, providing insights, improving diagnostics, and…

Artificial Intelligence · Computer Science 2025-12-05 Vignesh Kumar Kembu , Pierandrea Morandini , Marta Bianca Maria Ranzini , Antonino Nocera