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Recent advances in machine learning have opened new avenues for optimizing detector designs in high-energy physics, where the complex interplay of geometry, materials, and physics processes has traditionally posed a significant challenge.…

The convergence of artificial intelligence and materials science presents a transformative opportunity, but achieving true acceleration in discovery requires moving beyond task-isolated, fine-tuned models toward agentic systems that plan,…

Large language models (LLMs) are catalyzing the development of autonomous AI research agents for scientific and engineering discovery. We present FM Agent, a novel and general-purpose multi-agent framework that leverages a synergistic…

We introduce the concept of "Design Agents" for engineering applications, particularly focusing on the automotive design process, while emphasizing that our approach can be readily extended to other engineering and design domains. Our…

Artificial Intelligence · Computer Science 2025-12-04 Mohamed Elrefaie , Janet Qian , Raina Wu , Qian Chen , Angela Dai , Faez Ahmed

Large Language Models (LLMs) have emerged as powerful tools for accelerating scientific discovery, yet their static knowledge and hallucination issues hinder autonomous research applications. Recent advances integrate LLMs into agentic…

Artificial Intelligence · Computer Science 2025-12-23 Zeyu Xia , Jinzhe Ma , Congjie Zheng , Shufei Zhang , Yuqiang Li , Hang Su , P. Hu , Changshui Zhang , Xingao Gong , Wanli Ouyang , Lei Bai , Dongzhan Zhou , Mao Su

Finite element (FE) analysis guides the design and verification of nearly all manufactured objects. It is at the core of computational engineering, enabling simulation of complex physical systems, from fluids and solids to multiphysics…

Computational Engineering, Finance, and Science · Computer Science 2026-04-15 Rushikesh Deotale , Adithya Srinivasan , Yuan Tian , Tianyi Zhang , Pavlos Vlachos , Hector Gomez

We present the first language-model-driven agentic artificial intelligence (AI) system to autonomously execute multi-stage physics experiments on a production synchrotron light source. Implemented at the Advanced Light Source particle…

Accelerator Physics · Physics 2026-04-28 Thorsten Hellert , Drew Bertwistle , Simon C. Leemann , Antonin Sulc , Marco Venturini

Artificial Intelligence (AI) for design is a relatively new but active area of research across many disciplines. Surprisingly when it comes to designing detectors with AI this is an area at its infancy. The Electron Ion Collider is the…

Instrumentation and Detectors · Physics 2022-05-11 Cristiano Fanelli

The design of alloys is a multi-scale problem that requires a holistic approach that involves retrieving relevant knowledge, applying advanced computational methods, conducting experimental validations, and analyzing the results, a process…

Artificial Intelligence · Computer Science 2024-07-16 Alireza Ghafarollahi , Markus J. Buehler

Foundation models have reshaped AI by unifying fragmented architectures into scalable backbones with multimodal reasoning and contextual adaptation. In parallel, the long-standing notion of AI agents, defined by the sensing-decision-action…

Machine Learning · Computer Science 2025-10-02 Sicong Liu , Weiye Wu , Xiangrui Xu , Teng Li , Bowen Pang , Bin Guo , Zhiwen Yu

The prevailing paradigm in AI for physical systems (scaling general-purpose foundation models toward universal multimodal reasoning) confronts a fundamental barrier at the control interface. Recent benchmarks show that even frontier…

Artificial Intelligence · Computer Science 2026-05-21 Yoon Pyo Lee , Samrendra Roy , Jay Yoo , Kazuma Kobayashi , Sajedul Talukder , Seid Koric , Souvik Chakraborty , Syed Bahauddin Alam

Large language models (LLMs) have demonstrated remarkable capabilities across diverse tasks, but optimizing LLM-based agentic systems remains challenging due to the vast search space of agent configurations, prompting strategies, and…

Machine Learning · Computer Science 2026-03-02 Patara Trirat , Wonyong Jeong , Sung Ju Hwang

The rapid advancement of artificial intelligence, particularly autonomous agentic systems based on Large Language Models (LLMs), presents new opportunities to accelerate drug discovery by improving in-silico modeling and reducing dependence…

Recent advances in agentic AI have shifted the focus from standalone Large Language Models (LLMs) to integrated systems that combine LLMs with tools, memory, and other agents to perform complex tasks. These multi-agent architectures enable…

Multiagent Systems · Computer Science 2025-12-17 Sreemaee Akshathala , Bassam Adnan , Mahisha Ramesh , Karthik Vaidhyanathan , Basil Muhammed , Kannan Parthasarathy

We study mathematical discovery through the lens of neurosymbolic reasoning, where an AI agent powered by a large language model (LLM), coupled with symbolic computation tools, and human strategic direction, jointly produced a new result in…

Artificial Intelligence · Computer Science 2026-03-10 Hai Xia , Carla P. Gomes , Bart Selman , Stefan Szeider

As particle accelerators grow in complexity, traditional control methods face increasing challenges in achieving optimal performance. This paper envisions a paradigm shift: a decentralized multi-agent framework for accelerator control,…

Accelerator Physics · Physics 2025-09-04 Antonin Sulc , Thorsten Hellert , Raimund Kammering , Hayden Hoschouer , Jason St. John

Large-language-model (LLM)-based AI agents have recently showcased impressive versatility by employing dynamic reasoning, an adaptive, multi-step process that coordinates with external tools. This shift from static, single-turn inference to…

Machine Learning · Computer Science 2026-01-08 Jiin Kim , Byeongjun Shin , Jinha Chung , Minsoo Rhu

Analog/mixed-signal circuits are key for interfacing electronics with the physical world. Their design, however, remains a largely handcrafted process, resulting in long and error-prone design cycles. While the recent rise of AI-based…

Machine Learning · Computer Science 2026-01-15 Mohsen Ahmadzadeh , Kaichang Chen , Georges Gielen

AI agents are emerging as a dominant workload in a wide range of applications, promising to be the vehicle that delivers the promised benefits of AI to enterprises and consumers. Unlike conventional software or static inference, agentic…

Machine Learning · Computer Science 2025-07-29 Zain Asgar , Michelle Nguyen , Sachin Katti

We present Diagrammatica, a symbolic computation extension to the HEPTAPOD agentic framework, which enables LLM agents to plan and execute multi-step theoretical calculations. Symbolic computation poses a distinctive reliability challenge…

High Energy Physics - Phenomenology · Physics 2026-03-31 Tony Menzo , Alexander Roman , George T. Fleming , Sergei Gleyzer , Konstantin T. Matchev , Stephen Mrenna
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