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Linear models are widely used in computational neuroimaging to identify biomarkers associated with brain pathologies. However, interpreting the learned weights remains challenging, as they do not always yield clinically meaningful insights.…

Machine Learning · Computer Science 2026-04-23 Sara Petiton , Antoine Grigis , Raphaël Vock , Edouard Duchesnay

Drawing inspiration from neurosciences, artificial neural networks (ANNs) have evolved from shallow architectures to highly complex, deep structures, yielding exceptional performance in auditory recognition tasks. However, traditional ANNs…

Neurons and Cognition · Quantitative Biology 2025-02-24 Haidong Wang , Pengfei Xiao , Ao Liu , Jianhua Zhang , Qia Shan

Despite the rapid pace at which deep networks are improving on standardized vision benchmarks, they are still outperformed by humans on real-world vision tasks. One solution to this problem is to make deep networks more brain-like. Although…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Niranjan Rajesh , Georgin Jacob , SP Arun

Representational similarity metrics are fundamental tools in neuroscience and AI, yet we lack systematic comparisons of their discriminative power across model families. We introduce a quantitative framework to evaluate representational…

Machine Learning · Computer Science 2025-12-10 Jialin Wu , Shreya Saha , Yiqing Bo , Meenakshi Khosla

Recent studies suggest that the representations learned by large language models (LLMs) are partially aligned to those of the human brain. However, whether and why this alignment score arises from a similar sequence of computations remains…

Machine Learning · Computer Science 2025-12-02 Joséphine Raugel , Stéphane d'Ascoli , Jérémy Rapin , Valentin Wyart , Jean-Rémi King

While interpretability methods identify a model's learned concepts, they overlook the relationships between concepts that make up its abstractions and inform its ability to generalize to new data. To assess whether models' have learned…

Machine Learning · Computer Science 2025-11-04 Angie Boggust , Hyemin Bang , Hendrik Strobelt , Arvind Satyanarayan

Activation-alignment measures such as Representational Similarity Analysis (RSA), Canonical Correlation Analysis (CCA), and Centered Kernel Alignment (CKA) are widely used to compare biological and artificial neural representations. Recent…

Machine Learning · Computer Science 2026-05-08 Amirhossein Yavari , Farnaz Zamani Esfahlani

We present an exploration of machine learning architectures for predicting brain responses to realistic images on occasion of the Algonauts Challenge 2023. Our research involved extensive experimentation with various pretrained models.…

Neurons and Cognition · Quantitative Biology 2023-09-20 Riccardo Chimisso , Sathya Buršić , Paolo Marocco , Giuseppe Vizzari , Dimitri Ognibene

AI alignment refers to models acting towards human-intended goals, preferences, or ethical principles. Given that most large-scale deep learning models act as black boxes and cannot be manually controlled, analyzing the similarity between…

Computer Vision and Pattern Recognition · Computer Science 2023-10-23 Jiyoung Lee , Seungho Kim , Seunghyun Won , Joonseok Lee , Marzyeh Ghassemi , James Thorne , Jaeseok Choi , O-Kil Kwon , Edward Choi

While brain-inspired artificial intelligence(AI) has demonstrated promising results, current understanding of the parallels between artificial neural networks (ANNs) and human brain processing remains limited: (1) unimodal ANN studies fail…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Yudan Ren , Xinlong Wang , Kexin Wang , Tian Xia , Zihan Ma , Zhaowei Li , Xiangrong Bi , Xiao Li , Xiaowei He

What makes an artificial system a good model of intelligence? The classical test proposed by Alan Turing focuses on behavior, requiring that an artificial agent's behavior be indistinguishable from that of a human. While behavioral…

Neurons and Cognition · Quantitative Biology 2025-02-27 Jenelle Feather , Meenakshi Khosla , N. Apurva Ratan Murty , Aran Nayebi

As artificial intelligence increasingly drives critical decisions, the ability to genuinely explain how neural networks make predictions is essential for trust. Yet, most current explanation methods offer post-hoc rationalizations rather…

Machine Learning · Computer Science 2026-05-08 Corentin Lobet , Francesca Chiaromonte

Visual object recognition -- the behavioral ability to rapidly and accurately categorize many visually encountered objects -- is core to primate cognition. This behavioral capability is algorithmically impressive because of the myriad…

Neurons and Cognition · Quantitative Biology 2023-12-12 Kohitij Kar , James J DiCarlo

Predictive coding has emerged as an influential normative model of neural computation, with numerous extensions and applications. As such, much effort has been put into mapping PC faithfully onto the cortex, but there are issues that remain…

Neurons and Cognition · Quantitative Biology 2023-03-07 Siavash Golkar , Tiberiu Tesileanu , Yanis Bahroun , Anirvan M. Sengupta , Dmitri B. Chklovskii

Artificial Intelligence (AI) systems based solely on neural networks or symbolic computation present a representational complexity challenge. While minimal representations can produce behavioral outputs like locomotion or simple…

Neurons and Cognition · Quantitative Biology 2022-10-19 Bradly Alicea , Jesse Parent

Brain networks are typically represented by adjacency matrices, where each node corresponds to a brain region. In traditional brain network analysis, nodes are assumed to be matched across individuals, but the methods used for node matching…

Methodology · Statistics 2025-03-21 Martin Cole , Yang Xiang , Will Consagra , Anuj Srivastava , Xing Qiu , Zhengwu Zhang

In cognitive science and AI, a longstanding question is whether machines learn representations that align with those of the human mind. While current models show promise, it remains an open question whether this alignment is superficial or…

Neurons and Cognition · Quantitative Biology 2025-10-27 Craig Sanders , Billy Dickson , Sahaj Singh Maini , Robert Nosofsky , Zoran Tiganj

Computational modeling plays an increasingly important role in neuroscience, highlighting the philosophical question of how computational models explain. In the context of neural network models for neuroscience, concerns have been raised…

Neurons and Cognition · Quantitative Biology 2021-04-15 Rosa Cao , Daniel Yamins

A small but growing body of work has shown that machine learning models which better align with human vision have also exhibited higher robustness to adversarial examples, raising the question: can human-like perception make models more…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Blaine Hoak , Kunyang Li , Patrick McDaniel

Recent advances in vision-language models (VLMs) have achieved remarkable performance on standard medical benchmarks, yet their true clinical reasoning ability remains unclear. Existing datasets predominantly emphasize classification…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Miao Jing , Mengting Jia , Junling Lin , Zhongxia Shen , Huan Gao , Mingkun Xu , Shangyang Li