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The living cell expends energetic and material resources to reliably process information from its environment. To do so, it utilises unreliable molecular circuitry that is subject to thermal and other fluctuations. Here, we argue that…

Soft Condensed Matter · Physics 2022-04-12 Kabir Husain , Sriram Ramaswamy , Madan Rao

We need much better understanding of information processing and computation as its primary form. Future progress of new computational devices capable of dealing with problems of big data, internet of things, semantic web, cognitive robotics…

General Literature · Computer Science 2013-12-10 Mark Burgin , Gordana Dodig-Crnkovic

This paper proposes a variational approach to describe the evolution of organization of complex systems from first principles, as increased efficiency of physical action. Most simply stated, physical action is the product of the energy and…

Adaptation and Self-Organizing Systems · Physics 2014-07-29 Georgi Yordanov Georgiev , Kaitlin Henry , Timothy Bates , Erin Gombos , Alexander Casey , Michael Daly , Amrit Vinod , Hyunseung Lee

We present a simple discrete model for the non-linear spatial interaction of different kinds of ``subpopulations'' composed of identical moving entities like particles, bacteria, individuals, etc. The model allows to mimic a variety of…

Statistical Mechanics · Physics 2007-05-23 Dirk Helbing , Tadeusz Platkowski

Stochastic Schr\"odinger equations that govern the dynamics of open quantum systems are given by the equations for signal processing. In particular, the Brownian motion that drives the wave function of the system does not represent noise,…

Biological Physics · Physics 2022-09-28 Dorje C. Brody

Physical analogs have shown considerable promise for understanding the behavior of complex adaptive systems, including macroeconomics, biological systems, social networks, and electric power markets. Many of today's most challenging…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 David P. Chassin , Joel Malard , Christian Posse

A physicalistic argument can support the idea that cognition is an emergent property driven by dissipation. This argument suggests that cognition arises not from any fiat desire to understand the world, but rather because a certain type of…

General Physics · Physics 2024-01-03 Karl Svozil

Stochastic thermodynamics as reviewed here systematically provides a framework for extending the notions of classical thermodynamics like work, heat and entropy production to the level of individual trajectories of well-defined…

Statistical Mechanics · Physics 2015-06-05 Udo Seifert

The observable behavior of a complex system reflects the mechanisms governing the internal interactions between the system's components and the effect of external perturbations. Here we show that by capturing the simultaneous activity of…

Disordered Systems and Neural Networks · Physics 2009-11-10 M. Argollo de Menezes , A. -L. Barabasi

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

Given that observational and numerical climate data are being produced at ever more prodigious rates, increasingly sophisticated and automated analysis techniques have become essential. Deep learning is quickly becoming a standard approach…

Fluid Dynamics · Physics 2017-09-12 A. Rupe , J. P. Crutchfield , K. Kashinath , Prabhat

Living microorganisms have evolved dedicated sensory machinery to detect environmental perturbations, processing these signals through biochemical networks to guide behavior. Replicating such capabilities in synthetic active matter remains…

Soft Condensed Matter · Physics 2025-12-25 Diptabrata Paul , Nikola Milosevic , Nico Scherf , Frank Cichos

A central question in developmental biology is how size and position are determined. The genetic code carries instructions on how to control these properties in order to regulate the pattern and morphology of structures in the developing…

Cell Behavior · Quantitative Biology 2016-12-05 Krishna Garikipati

Physical processes are computations only when we use them to externalize thought. Computation is the performance of one or more fixed processes within a contingent environment. We reformulate the Church-Turing thesis so that it applies to…

Multiagent Systems · Computer Science 2007-05-23 Russ Abbott

Biological machines like molecular motors and enzymes operate in dynamic cycles representable as stochastic flows on networks. Current stochastic dynamics describes such flows on fixed networks. Here, we develop a scalable approach to…

Statistical Mechanics · Physics 2026-03-02 Ying-Jen Yang , Ken A. Dill

Most complex networks serve as conduits for various dynamical processes, ranging from mass transfer by chemical reactions in the cell to packet transfer on the Internet. We collected data on the time dependent activity of five natural and…

Disordered Systems and Neural Networks · Physics 2009-11-10 M. Argollo de Menezes , A-L. Barabasi

Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…

Quantitative Methods · Quantitative Biology 2026-05-20 Antoine Diez , Jean Feydy

The problem of the insensitivity of the macroscopic behavior of any thermodynamical system to partitioning generates a bias between the reproducibility of its macroscopic behavior viewed as the simplest form of causality and its long-term…

General Physics · Physics 2007-05-23 Maria K. Koleva

Recent works suggest that pooling and sharing may constitute a fundamental mechanism for the evolution of cooperation in well-mixed fluctuating environments. The rationale is that, by reducing the amplitude of fluctuations, pooling and…

Adaptation and Self-Organizing Systems · Physics 2019-07-03 Viktor Stojkoski , Zoran Utkovski , Lasko Basnarkov , Ljupco Kocarev

Growth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these…

Populations and Evolution · Quantitative Biology 2007-05-23 Michele Bezzi , Andrea Ciliberto