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Related papers: Clinically Interpretable Sepsis Early Warning via …

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Sepsis remains one of the most complex and heterogeneous syndromes in intensive care, characterized by diverse physiological trajectories and variable responses to treatment. While deep learning models perform well in the early prediction…

Machine Learning · Computer Science 2026-04-01 Vincent Lemaire , Nédra Meloulli , Pierre Jaquet

Sepsis is a life-threatening condition that requires rapid detection and treatment to prevent progression to severe sepsis, septic shock, or multi-organ failure. Despite advances in medical technology, it remains a major challenge for…

Machine Learning · Computer Science 2025-11-11 Atharva Thakur , Shruti Dhumal

Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…

Machine Learning · Computer Science 2026-01-01 Alireza Rafiei , Farshid Hajati , Alireza Rezaee , Amirhossien Panahi , Shahadat Uddin

Sepsis is a life-threatening disease with high morbidity, mortality and healthcare costs. The early prediction and administration of antibiotics and intravenous fluids is considered crucial for the treatment of sepsis and can save…

Computation and Language · Computer Science 2021-07-26 Fred Qin , Vivek Madan , Ujjwal Ratan , Zohar Karnin , Vishaal Kapoor , Parminder Bhatia , Taha Kass-Hout

Large Language Models (LLMs) are increasingly deployed as autonomous agents capable of reasoning, planning, and acting within interactive environments. Despite their growing capability to perform multi-step reasoning and decision-making…

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

Artificial Intelligence · Computer Science 2025-02-24 Brian Hyeongseok Kim , Chao Wang

Agent-based simulation is crucial for modeling complex human behavior, yet traditional approaches require extensive domain knowledge and large datasets. In data-scarce healthcare settings where historic and counterfactual data are limited,…

Artificial Intelligence · Computer Science 2025-04-01 Sarah Martinson , Lingkai Kong , Cheol Woo Kim , Aparna Taneja , Milind Tambe

Large Language Models (LLMs) have been shown to encode clinical knowledge. Many evaluations, however, rely on structured question-answer benchmarks, overlooking critical challenges of interpreting and reasoning about unstructured clinical…

Computation and Language · Computer Science 2026-04-01 Meghal Dani , Muthu Jeyanthi Prakash , Filip Rosa , Zeynep Akata , Stefanie Liebe

Timely identification and accurate risk stratification of cardiovascular disease (CVD) remain essential for reducing global mortality. While existing prediction models primarily leverage structured data, unstructured clinical notes contain…

Computation and Language · Computer Science 2025-07-16 Haowei Yang , Ziyu Shen , Junli Shao , Luyao Men , Xinyue Han , Jing Dong

Sepsis management in the ICU requires sequential treatment decisions under rapidly evolving patient physiology. Although large language models (LLMs) encode broad clinical knowledge and can reason over guidelines, they are not inherently…

Artificial Intelligence · Computer Science 2026-05-15 Minghao Wu , Yuting Yan , Zhenyang Cai , Ke Ji , Chuangsen Fang , Ziying Sheng , Xidong Wang , Rongsheng Wang , Hejia Zhang , Shuang Li , Benyou Wang , Hongyuan Zha

Sepsis is a life threatening medical condition that occurs when the body has an extreme response to infection, leading to widespread inflammation, organ failure, and potentially death. Because sepsis can worsen rapidly, early detection is…

Machine Learning · Computer Science 2025-05-07 Oyindolapo O. Komolafe , Zhimin Mei , David Morales Zarate , Gregory William Spangenberg

Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual…

Machine Learning · Computer Science 2025-09-03 Hejiang Cai , Di Wu , Ji Xu , Xiang Liu , Yiziting Zhu , Xin Shu , Yujie Li , Bin Yi

Sepsis remains one of the leading causes of mortality in intensive care units, where timely and accurate treatment decisions can significantly impact patient outcomes. In this work, we propose an interpretable decision support framework.…

Machine Learning · Computer Science 2026-01-21 Punit Kumar , Vaibhav Saran , Divyesh Patel , Nitin Kulkarni , Alina Vereshchaka

Advances in large language models (LLMs) have enabled a wide range of applications. However, depression prediction is hindered by the lack of large-scale, high-quality, and rigorously annotated datasets. This study introduces DepressLLM,…

Computation and Language · Computer Science 2025-08-13 Sehwan Moon , Aram Lee , Jeong Eun Kim , Hee-Ju Kang , Il-Seon Shin , Sung-Wan Kim , Jae-Min Kim , Min Jhon , Ju-Wan Kim

Sepsis is a leading cause of death in the Intensive Care Units (ICU). Early detection of sepsis is critical for patient survival. In this paper, we propose a multimodal Transformer model for early sepsis prediction, using the physiological…

Machine Learning · Computer Science 2022-03-29 Yuqing Wang , Yun Zhao , Rachael Callcut , Linda Petzold

Clinical case reports and discharge summaries may be the most complete and accurate summarization of patient encounters, yet they are finalized, i.e., timestamped after the encounter. Complementary structured data streams become available…

Computation and Language · Computer Science 2026-05-13 Shahriar Noroozizadeh , Jeremy C. Weiss

Machine learning for early prediction in medicine has recently shown breakthrough performance, however, the focus on improving prediction accuracy has led to a neglect of faithful explanations that are required to gain the trust of medical…

Computation and Language · Computer Science 2025-12-04 Michael Staniek , Artem Sokolov , Stefan Riezler

Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

We present Clinical Prediction with Large Language Models (CPLLM), a method that involves fine-tuning a pre-trained Large Language Model (LLM) for clinical disease and readmission prediction. We utilized quantization and fine-tuned the LLM…

Computation and Language · Computer Science 2024-05-03 Ofir Ben Shoham , Nadav Rappoport

With the increasing availability of patient data, modern medicine is shifting towards prospective healthcare. Electronic health records offer a variety of information useful for clinical patient characterization and the development of…

Machine Learning · Computer Science 2025-05-27 Fabio Azzalini , Tommaso Dolci , Marco Vagaggini
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