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Machine learning in medical imaging during clinical routine is impaired by changes in scanner protocols, hardware, or policies resulting in a heterogeneous set of acquisition settings. When training a deep learning model on an initial…

Computer Vision and Pattern Recognition · Computer Science 2022-03-16 Matthias Perkonigg , Johannes Hofmanninger , Christian Herold , Helmut Prosch , Georg Langs

Deep learning models perform best when tested on target (test) data domains whose distribution is similar to the set of source (train) domains. However, model generalization can be hindered when there is significant difference in the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-19 Pulkit Khandelwal , Paul Yushkevich

Machine learning algorithms have revolutionized different fields, including natural language processing, computer vision, signal processing, and medical data processing. Despite the excellent capabilities of machine learning algorithms in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Gita Sarafraz , Armin Behnamnia , Mehran Hosseinzadeh , Ali Balapour , Amin Meghrazi , Hamid R. Rabiee

Batch Normalization (BN) and its variants have delivered tremendous success in combating the covariate shift induced by the training step of deep learning methods. While these techniques normalize feature distributions by standardizing with…

Machine Learning · Computer Science 2021-05-06 Mandy Lu , Qingyu Zhao , Jiequan Zhang , Kilian M. Pohl , Li Fei-Fei , Juan Carlos Niebles , Ehsan Adeli

Deep learning-based methods deliver state-of-the-art performance for solving inverse problems that arise in computational imaging. These methods can be broadly divided into two groups: (1) learn a network to map measurements to the signal…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Nebiyou Yismaw , Ulugbek S. Kamilov , M. Salman Asif

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Due to the scarcity of annotated data and the substantial computational costs of model, conventional tuning methods in medical image segmentation face critical challenges. Current approaches to adapting pretrained models, including…

Computer Vision and Pattern Recognition · Computer Science 2025-12-05 Chenlin Xu , Lei Zhang , Lituan Wang , Xinyu Pu , Pengfei Ma , Guangwu Qian , Zizhou Wang , Yan Wang

Deep learning has shown remarkable progress in medical image semantic segmentation, yet its success heavily depends on large-scale expert annotations and consistent data distributions. In practice, annotations are scarce, and images are…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Ba-Thinh Lam , Thanh-Huy Nguyen , Hoang-Thien Nguyen , Quang-Khai Bui-Tran , Nguyen Lan Vi Vu , Phat K. Huynh , Ulas Bagci , Min Xu

Batch normalization was introduced in 2015 to speed up training of deep convolution networks by normalizing the activations across the current batch to have zero mean and unity variance. The results presented here show an interesting aspect…

Computer Vision and Pattern Recognition · Computer Science 2018-02-22 Mohamed Hajaj , Duncan Gillies

Brain disorders are a major challenge to global health, causing millions of deaths each year. Accurate diagnosis of these diseases relies heavily on advanced medical imaging techniques such as Magnetic Resonance Imaging (MRI) and Computed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Xuran Zhu

Domain-invariant representation learning is a powerful method for domain generalization. Previous approaches face challenges such as high computational demands, training instability, and limited effectiveness with high-dimensional data,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Yuheng Xu , Taiping Zhang

Medical imaging datasets usually exhibit domain shift due to the variations of scanner vendors, imaging protocols, etc. This raises the concern about the generalization capacity of machine learning models. Domain generalization (DG), which…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Chenxin Li , Qi Qi , Xinghao Ding , Yue Huang , Dong Liang , Yizhou Yu

High content imaging assays can capture rich phenotypic response data for large sets of compound treatments, aiding in the characterization and discovery of novel drugs. However, extracting representative features from high content images…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Johan Fredin Haslum , Christos Matsoukas , Karl-Johan Leuchowius , Erik Müllers , Kevin Smith

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

Training Deep Neural Networks is complicated by the fact that the distribution of each layer's inputs changes during training, as the parameters of the previous layers change. This slows down the training by requiring lower learning rates…

Machine Learning · Computer Science 2015-03-03 Sergey Ioffe , Christian Szegedy

Deep learning models for medical image analysis often suffer from performance degradation when applied to data from different scanners or protocols, a phenomenon known as domain shift. This study investigates this challenge in the context…

Medical Physics · Physics 2025-08-29 Peyman Sharifian , Mohammad Saber Azimi , AliReza Karimian , Hossein Arabi

Most standard learning approaches lead to fragile models which are prone to drift when sequentially trained on samples of a different nature - the well-known "catastrophic forgetting" issue. In particular, when a model consecutively learns…

Computer Vision and Pattern Recognition · Computer Science 2021-04-09 Riccardo Volpi , Diane Larlus , Grégory Rogez

Generalising deep models to new data from new centres (termed here domains) remains a challenge. This is largely attributed to shifts in data statistics (domain shifts) between source and unseen domains. Recently, gradient-based…

Computer Vision and Pattern Recognition · Computer Science 2021-10-05 Xiao Liu , Spyridon Thermos , Alison O'Neil , Sotirios A. Tsaftaris

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

Deep learning algorithms have demonstrated tremendous success on challenging medical imaging problems. However, post-deployment, these algorithms are susceptible to data distribution variations owing to \emph{limited data issues} and…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Rahul Venkataramani , Hariharan Ravishankar , Saihareesh Anamandra
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