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The literature for count modeling provides useful tools to conduct causal inference when outcomes take non-negative integer values. Applied to the potential outcomes framework, we link the Bayesian causal inference literature to statistical…
Bayesian estimation is increasingly popular for performing model based inference to support policymaking. These data are often collected from surveys under informative sampling designs where subject inclusion probabilities are designed to…
The problem of finding the missing values of a matrix given a few of its entries, called matrix completion, has gathered a lot of attention in the recent years. Although the problem under the standard low rank assumption is NP-hard,…
X-chromosome is often excluded from the so called `whole-genome' association studies due to its intrinsic difference between males and females. One particular analytical challenge is the unknown status of X-inactivation, where one of the…
We consider the statistical inference for noisy incomplete binary (or 1-bit) matrix. Despite the importance of uncertainty quantification to matrix completion, most of the categorical matrix completion literature focuses on point estimation…
The interpretation of medical images is a challenging task, often complicated by the presence of artifacts, occlusions, limited contrast and more. Most notable is the case of chest radiography, where there is a high inter-rater variability…
Most empirical studies of complex networks do not return direct, error-free measurements of network structure. Instead, they typically rely on indirect measurements that are often error-prone and unreliable. A fundamental problem in…
It is not always clear how to adjust for control data in causal inference, balancing the goals of reducing bias and variance. We show how, in a setting with repeated experiments, Bayesian hierarchical modeling yields an adaptive procedure…
Table structure recognition is necessary for a comprehensive understanding of documents. Tables in unstructured business documents are tough to parse due to the high diversity of layouts, varying alignments of contents, and the presence of…
Modern regression applications can involve hundreds or thousands of variables which motivates the use of variable selection methods. Bayesian variable selection defines a posterior distribution on the possible subsets of the variables…
To accomplish correct Bayesian inference from weak lensing shear data requires a complete statistical description of the data. The natural framework to do this is a Bayesian Hierarchical Model, which divides the chain of reasoning into…
Breast cancer is a heterogeneous disease with different molecular subtypes, clinical behavior, treatment responses as well as survival outcomes. The development of a reliable, accurate, available and inexpensive method to predict the…
Targeted amplicon panels are widely used in oncology diagnostics, but providing per-gene performance guarantees for copy number variant (CNV) detection remains challenging due to amplification artifacts, process-mismatch heterogeneity, and…
The analysis of count data is commonly done using Poisson models. Negative binomial models are a straightforward and readily motivated generalization for the case of overdispersed data, i.e., when the observed variance is greater than…
Dynamic prediction of causal effects under different treatment regimes conditional on an individual's characteristics and longitudinal history is an essential problem in precision medicine. This is challenging in practice because outcomes…
We address the problem of two-variable causal inference without intervention. This task is to infer an existing causal relation between two random variables, i.e. $X \rightarrow Y$ or $Y \rightarrow X$ , from purely observational data. As…
Models for distributions of shapes contained within images can be widely used in biomedical applications ranging from tumor tracking for targeted radiation therapy to classifying cells in a blood sample. Our focus is on hierarchical…
In this paper, we consider the problem of testing independence in high-dimensional settings with missing data. Building upon a recently proposed Kendall-based statistic, we introduce two new modifications specifically designed to…
Purpose: Tracer-kinetic models can be used for the quantitative assessment of contrast-enhanced MRI data. However, the model-fitting can produce unreliable results due to the limited data acquired and the high noise levels. Such problems…
Repeating an imperfect biomarker test based on an initial result can introduce bias and influence misclassification risk. For example, in some blood donation settings, blood donors' hemoglobin is remeasured when the initial measurement…