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Is reduction always a good scientific strategy? Does it always lead to a gain in information? The very existence of the special sciences above and beyond physics seems to hint no. Previous research has shown that dimension reduction…

Information Theory · Computer Science 2021-04-28 Thomas Varley , Erik Hoel

The current theory of evolution is almost the one Darwin and Wallace proposed two centuries ago and the following discoveries e.g., Mendelian genetics and neutral mutation theory have not made significant modifications. The current…

Populations and Evolution · Quantitative Biology 2023-09-14 Reza Rahmanzadeh

Epigenetics has captured the attention of scientists in the past decades, yet its scope has been continuously changing. In this paper, we give an overview on how and why its definition has evolved and suggest several clarification on the…

Subcellular Processes · Quantitative Biology 2015-02-05 Evelyne Saade , Vasily Ogryzko

How specific environmental contexts contribute to the robustness and variation of developmental trajectories and evolutionary transitions is a central point in Eco-Evo-Devo. However, the articulation of ecological, evolutionary and…

Populations and Evolution · Quantitative Biology 2019-08-16 Natsuko Rivera-Yoshida , Alejandra Hernandez-Teran , Ana E. Escalante , Mariana Benitez

Competition between random genetic drift and natural selection plays a central role in evolution: Whereas non-beneficial mutations often prevail in small populations by chance, mutations that sweep through large populations typically confer…

Populations and Evolution · Quantitative Biology 2009-11-13 Oskar Hallatschek , Pascal Hersen , Sharad Ramanathan , David R. Nelson

Mutation has traditionally been regarded as an important operator in evolutionary algorithms. In particular, there have been many experimental studies which showed the effectiveness of adapting mutation rates for various static optimization…

Artificial Intelligence · Computer Science 2011-06-06 Tianshi Chen , Yunji Chen , Ke Tang , Guoliang Chen , Xin Yao

Cooperation is a widespread natural phenomenon yet current evolutionary thinking is dominated by the paradigm of selfish competition. Recent advanced in many fronts of Biology and Non-linear Physics are helping to bring cooperation to its…

Populations and Evolution · Quantitative Biology 2014-06-13 Octavio Miramontes , Og DeSouza

Rediscovering a new function for something can be just as important as the discovery itself. In 1982, Stephen Jay Gould and Elisabeth Vrba named this phenomenon Exaptation to describe a radical shift in the function of a specific trait…

Stochastic phenotype switching has been suggested to play a beneficial role in microbial populations by leading to the division of labour among cells, or ensuring that at least some of the population survives an unexpected change in…

Populations and Evolution · Quantitative Biology 2016-02-02 Andrew C. Tadrowski , Martin R. Evans , Bartlomiej Waclaw

The effect of bias on hypothesis formation is characterized for an automated data-driven projection pursuit neural network to extract and select features for binary classification of data streams. This intelligent exploratory process…

Machine Learning · Computer Science 2022-01-05 John Patterson , Chris Avery , Tyler Grear , Donald J. Jacobs

Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inheritance of a gradualistic view that has been challenged at…

Populations and Evolution · Quantitative Biology 2018-07-27 Jacobo Aguirre , Pablo Catalán , José A. Cuesta , Susanna Manrubia

In this paper we examine how concurrency has been embodied in mainstream programming languages. In particular, we rely on the evolutionary talking borrowed from biology to discuss major historical landmarks and crucial concepts that shaped…

Programming Languages · Computer Science 2015-07-29 Silvia Crafa

Color naming in natural languages is not arbitrary: it reflects efficient partitions of perceptual color space modulated by the relative needs to communicate about different colors. These psychophysical and communicative constraints help…

Populations and Evolution · Quantitative Biology 2023-05-09 Colin R. Twomey , David H. Brainard , Joshua B. Plotkin

The grand challenges in biology today are being shaped by powerful high-throughput technologies that have revealed the genomes of many organisms, global expression patterns of genes and detailed information about variation within…

Statistics Theory · Mathematics 2007-06-13 Lior Pachter , Bernd Sturmfels

We investigate the selective forces that promote the emergence of modularity in nature. We demonstrate the spontaneous emergence of modularity in a population of individuals that evolve in a changing environment. We show that the level of…

Populations and Evolution · Quantitative Biology 2009-11-13 Jun Sun , Michael W. Deem

To discover new drugs is to seek and to prove causality. As an emerging approach leveraging human knowledge and creativity, data, and machine intelligence, causal inference holds the promise of reducing cognitive bias and improving decision…

Quantitative Methods · Quantitative Biology 2025-04-09 Tom Michoel , Jitao David Zhang

Enzyme is the major workhorse to carry out the diverse cellular functions. It catalyzes the biological reactions with a high specificity, with its topology playing a crucial role. For ecologically safe production of numerous bioproducts…

Biomolecules · Quantitative Biology 2021-06-04 Prabha Sankara Narayanan , Ashish Runthala

This study introduces a novel theoretical framework, the Stacked Autoencoder Evolution Hypothesis, which proposes that biological evolutionary systems operate through multi-layered self-encoding and decoding processes, analogous to stacked…

Neural and Evolutionary Computing · Computer Science 2026-02-03 Hiroyuki Iizuka

The selection pressures that have shaped the evolution of complex traits in humans remain largely unknown, and in some contexts highly contentious, perhaps above all where they concern mean trait differences among groups. To date, the…

Populations and Evolution · Quantitative Biology 2020-10-08 Arbel Harpak , Molly Przeworski

The mutation process in evolution strategies has been interlinked with the normal distribution since its inception. Many lines of reasoning have been given for this strong dependency, ranging from maximum entropy arguments to the need for…

Neural and Evolutionary Computing · Computer Science 2025-04-11 Jacob de Nobel , Diederick Vermetten , Hao Wang , Anna V. Kononova , Günter Rudolph , Thomas Bäck
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