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Quadratic Unconstrained Binary Optimization (QUBO) is a standard NP-hard optimization problem. Recently, it has gained renewed interest through quantum computing, as QUBOs directly reduce to the Ising model, on which quantum annealing…

Quantum Physics · Physics 2026-03-16 Katalin Friedl , Levente Gegő , László Kabódi , Viktória Nemkin

The prospect of quantum solutions for complicated optimization problems is contingent on mapping the original problem onto a tractable quantum energy landscape, e.g. an Ising-type Hamiltonian. Subsequently, techniques like adiabatic…

Quantum Physics · Physics 2025-10-17 Sebastian Egginger , Kristina Kirova , Sonja Bruckner , Stefan Hillmich , Richard Kueng

The Travelling Salesman Problem (TSP) is an important combinatorial optimisation problem, and is usually solved on a quantum computer using a Quadratic Unconstrained Binary Optimisation (QUBO) formulation or a Higher Order Binary…

Quantum Physics · Physics 2024-06-21 Daniel Goldsmith , Joe Day-Evans

Solving optimization problems is a key task for which quantum computers could possibly provide a speedup over the best known classical algorithms. Particular classes of optimization problems including semi-definite programming (SDP) and…

Combinatorial optimization problems are ubiquitous in industry. In addition to finding a solution with minimum cost, problems of high relevance involve a number of constraints that the solution must satisfy. Variational quantum algorithms…

We extend the family of problems that may be implemented on an adiabatic quantum optimizer (AQO). When a quadratic optimization problem has at least one set of discrete controls and the constraints are linear, we call this a quadratic…

Quantum Physics · Physics 2014-07-16 Rishabh Chandra , N. Tobias Jacobson , Jonathan E. Moussa , Steven H. Frankel , Sabre Kais

With the applications of quantum computing becoming more and more widespread, finding ways that allow end users without experience in the field to apply quantum computers to solve their individual problems is becoming a crucial task.…

Quantum Physics · Physics 2024-04-18 Damian Rovara , Nils Quetschlich , Robert Wille

The standard approach to encoding constraints in quantum optimization is the quadratic penalty method. Quadratic penalties introduce additional couplings and energy scales, which can be detrimental to the performance of a quantum optimizer.…

Quantum Physics · Physics 2024-12-17 Puya Mirkarimi , David C. Hoyle , Ross Williams , Nicholas Chancellor

Linear regression is a popular machine learning approach to learn and predict real valued outputs or dependent variables from independent variables or features. In many real world problems, its beneficial to perform sparse linear regression…

Machine Learning · Computer Science 2021-06-07 Surya Sai Teja Desu , P. K. Srijith , M. V. Panduranga Rao , Naveen Sivadasan

Quadratic unconstrained binary optimization (QUBO) has become the standard format for optimization using quantum computers, i.e., for both the quantum approximate optimization algorithm (QAOA) and quantum annealing (QA). We present a…

Quantum Physics · Physics 2022-04-26 Thomas Gabor , Marian Lingsch Rosenfeld , Sebastian Feld , Claudia Linnhoff-Popien

In this paper we consider a nonconvex optimization problem with nonlinear equality constraints. We assume that both, the objective function and the functional constraints, are locally smooth. For solving this problem, we propose a…

Optimization and Control · Mathematics 2024-12-02 Lahcen El Bourkhissi , Ion Necoara

In this paper, we introduce three QUBO (Quadratic Unconstrained Binary Optimization) relaxations for the sparsest $k$-subgraph (SkS) problem: a quadratic penalty relaxation, a Lagrangian relaxation, and an augmented Lagrangian relaxation.…

Optimization and Control · Mathematics 2025-09-11 Omkar Bihani , Roman Kužel , Janez Povh , Dunja Pucher

We propose an approach to solving constrained combinatorial optimization problems based on embedding the concept of Lagrangian duality into the framework of adiabatic quantum computation. Within the setting of circuit-model fault-tolerant…

Optimization and Control · Mathematics 2024-04-30 Einar Gabbassov , Gili Rosenberg , Artur Scherer

Accurate prediction of mRNA secondary structure is critical for understanding gene expression, translation efficiency, and advancing mRNA-based therapeutics. However, the combinatorial complexity of possible foldings, especially in long…

The Quadratic Unconstrained Binary Optimization (QUBO) modeling and solution framework is a requirement for quantum and digital annealers. However optimality for QUBO problems of any practical size is extremely difficult to achieve. In…

Artificial Intelligence · Computer Science 2021-05-13 Amit Verma , Mark Lewis

Recent advances in quantum technology have led to the development and manufacturing of experimental programmable quantum annealers that promise to solve certain combinatorial optimization problems of practical relevance faster than their…

Quantum Physics · Physics 2016-05-31 Itay Hen , Federico M. Spedalieri

Quantum optimization holds promise for addressing classically intractable combinatorial problems, yet a standardized framework for benchmarking its performance, particularly in terms of solution quality, computational speed, and scalability…

Quantum Physics · Physics 2025-03-20 Monit Sharma , Hoong Chuin Lau

We propose a new methodology for parameterized constrained robust optimization, an important class of optimization problems under uncertainty, based on learning with a self-supervised penalty-based loss function. Whereas supervised learning…

Optimization and Control · Mathematics 2025-03-10 Wyame Benslimane , Paul Grigas

We propose a new method for solving binary optimization problems under inequality constraints using a quantum annealer. To deal with inequality constraints, we often use slack variables, as in previous approaches. When we use slack…

Quantum Physics · Physics 2020-12-14 Kouki Yonaga , Masamichi J. Miyama , Masayuki Ohzeki

In this paper, we develop a way to encode several NP-Complete problems in Abstract Argumentation to Quadratic Unconstrained Binary Optimization (QUBO) problems. In this form, a solution for a QUBO problem involves minimizing a quadratic…

Quantum Physics · Physics 2024-09-10 Marco Baioletti , Francesco Santini