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Bayesian inference is often implemented using approximations, which can yield interval estimates that are too narrow, not fully capturing the uncertainty in the posterior distribution. We address the question of how to adjust these…

Methodology · Statistics 2026-03-23 Tiffany Cai , Philip Greengard , Ben Goodrich , Andrew Gelman

Recovering images from undersampled linear measurements typically leads to an ill-posed linear inverse problem, that asks for proper statistical priors. Building effective priors is however challenged by the low train and test overhead…

Artificial Intelligence · Computer Science 2017-11-29 Morteza Mardani , Hatef Monajemi , Vardan Papyan , Shreyas Vasanawala , David Donoho , John Pauly

Posterior sampling with the spike-and-slab prior [MB88], a popular multimodal distribution used to model uncertainty in variable selection, is considered the theoretical gold standard method for Bayesian sparse linear regression [CPS09,…

Machine Learning · Statistics 2025-03-05 Syamantak Kumar , Purnamrita Sarkar , Kevin Tian , Yusong Zhu

Abstract abridged. Eclipsing binary systems provide the opportunity to measure the fundamental parameters of their component stars in a stellar-model-independent way. This makes them ideal candidates for testing and calibrating theories of…

Instrumentation and Methods for Astrophysics · Physics 2024-02-12 Luc W. IJspeert , Andrew Tkachenko , Cole Johnston , Andrej Prša , Mark A. Wells , Conny Aerts

Recently, deep generative models have been used for posterior inference in inverse problems, including high-stakes applications in medical imaging and scientific discovery, where the uncertainty of a prediction can matter as much as the…

Machine Learning · Computer Science 2026-05-15 Yuxin Guo , Dongrui Deng , Pulkit Grover

Advances in sensing technology have made it possible to collect large volumes of high-dimensional time-series data. In fields like genetics and neuroscience, key questions concern whether directed relationships between variables can be…

Methodology · Statistics 2026-05-08 Sarah E. Heaps , Ian H. Jermyn , Yujiang Wang , Darren J. Wilkinson

Multivariate, heteroscedastic errors complicate statistical inference in many large-scale denoising problems. Empirical Bayes is attractive in such settings, but standard parametric approaches rest on assumptions about the form of the prior…

Statistics Theory · Mathematics 2024-01-02 Jake A. Soloff , Adityanand Guntuboyina , Bodhisattva Sen

We explore the use of a Neural Ratio Estimator (NRE) to determine the Hubble constant ($H_0$) in the context of time delay cosmography. Assuming a Singular Isothermal Ellipsoid (SIE) mass profile for the deflector, we simulate time delay…

Instrumentation and Methods for Astrophysics · Physics 2023-09-29 Ève Campeau-Poirier , Laurence Perreault-Levasseur , Adam Coogan , Yashar Hezaveh

Computational modeling is a key resource to gather insight into physical systems in modern scientific research and engineering. While access to large amount of data has fueled the use of Machine Learning (ML) to recover physical models from…

Machine Learning · Computer Science 2023-12-06 Simone Manti , Alessandro Lucantonio

Neural posterior estimation (NPE) and neural likelihood estimation (NLE) are machine learning approaches that provide accurate posterior, and likelihood, approximations in complex modeling scenarios, and in situations where conducting…

Machine Learning · Statistics 2024-11-20 David T. Frazier , Ryan Kelly , Christopher Drovandi , David J. Warne

Simulation-based inference (SBI) enables parameter estimation for complex stochastic models with intractable likelihoods when model simulation is feasible. Neural posterior estimation (NPE) is a popular SBI approach that often achieves…

Methodology · Statistics 2026-02-23 Ryan P. Kelly , David T. Frazier , David J. Warne , Christopher C. Drovandi

The ``differentiability gap'' presents a primary bottleneck in Earth system deep learning: since models cannot be trained directly on non-differentiable scientific metrics and must rely on smooth proxies (e.g., MSE), they often fail to…

Machine Learning · Computer Science 2026-04-14 Filippo Quarenghi , Ryan Cotsakis , Tom Beucler

The precision of photometric and spectroscopic observations has been systematically improved in the last decade, mostly thanks to space-borne photometric missions and ground-based spectrographs dedicated to finding exoplanets. The field of…

Simulator-based models are models for which the likelihood is intractable but simulation of synthetic data is possible. They are often used to describe complex real-world phenomena, and as such can often be misspecified in practice.…

Exponential random graph models (ERGMs) are flexible probabilistic frameworks to model statistical networks through a variety of network summary statistics. Conventional Bayesian estimation for ERGMs involves iteratively exchanging with an…

Methodology · Statistics 2025-04-15 Yefeng Fan , Simon White

Bayesian inference allows machine learning models to express uncertainty. Current machine learning models use only a single learnable parameter combination when making predictions, and as a result are highly overconfident when their…

Machine Learning · Computer Science 2022-02-23 Andrew Wood , Moshik Hershcovitch , Daniel Waddington , Sarel Cohen , Peter Chin

Bayesian Neural Networks (BNNs) often improve model calibration and predictive uncertainty quantification compared to point estimators such as maximum-a-posteriori (MAP). Similarly, deep ensembles (DEs) are also known to improve…

Machine Learning · Computer Science 2025-03-18 Mikkel Jordahn , Jonas Vestergaard Jensen , Mikkel N. Schmidt , Michael Riis Andersen

The mass discrepancy problem, observed in high-mass stars within eclipsing binaries, highlights systematic differences between dynamical and evolutionary mass estimates, challenging the accuracy of stellar evolution models. We aim to…

Solar and Stellar Astrophysics · Physics 2025-07-15 Nadya Serebriakova , Andrew Tkachenko , Cole Johnston , Krešimir Pavlovski , Conny Aerts

The paper is concerned with guaranteed a posteriori error estimates for a class of evolutionary problems related to poroelastic media governed by the quasi-static linear Biot equations. The system is decoupled employing the fixed-stress…

Numerical Analysis · Mathematics 2020-01-22 Kundan Kumar , Svetlana Kyas , Jan Nordbotten , Sergey Repin

The current standard Bayesian approach to model calibration, which assigns a Gaussian process prior to the discrepancy term, often suffers from issues of unidentifiability and computational complexity and instability. When the goal is to…

Methodology · Statistics 2019-09-13 Spencer Woody , Novin Ghaffari , Lauren Hund