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Clinical trials are central to medical progress because they help improve understanding of human health and the healthcare system. They play a key role in discovering new ways to detect, prevent, or treat diseases, and it is essential that…

Computation and Language · Computer Science 2025-10-16 Surya Tejaswi Yerramsetty , Almas Fathimah

Introduction: Clinical text classification using natural language processing (NLP) models requires adequate training data to achieve optimal performance. For that, 200-500 documents are typically annotated. The number is constrained by time…

Computation and Language · Computer Science 2026-01-23 Jaya Chaturvedi , Saniya Deshpande , Chenkai Ma , Robert Cobb , Angus Roberts , Robert Stewart , Daniel Stahl , Diana Shamsutdinova

Feature engineering is crucial for optimizing machine learning model performance, particularly in tabular data classification tasks. Leveraging advancements in natural language processing, this study presents a systematic approach to enrich…

Machine Learning · Computer Science 2024-11-07 Gjergji Kasneci , Enkelejda Kasneci

To enhance the robustness of the Light Gradient Boosting Machine (LightGBM) algorithm for image classification, a topological data analysis (TDA)-based robustness optimization algorithm for LightGBM, TDA-LightGBM, is proposed to address the…

Machine Learning · Computer Science 2024-06-21 Han Yang , Guangjun Qin , Ziyuan Liu , Yongqing Hu , Qinglong Dai

The deployment of Large Language Models (LLMs) in high-stakes clinical settings demands rigorous and reliable evaluation. However, existing medical benchmarks remain static, suffering from two critical limitations: (1) data contamination,…

Artificial Intelligence · Computer Science 2026-02-12 Zhiling Yan , Dingjie Song , Zhe Fang , Yisheng Ji , Xiang Li , Quanzheng Li , Lichao Sun

Clinical text classification is an important problem in medical natural language processing. Existing studies have conventionally focused on rules or knowledge sources-based feature engineering, but only a few have exploited effective…

Computation and Language · Computer Science 2018-07-23 Liang Yao , Chengsheng Mao , Yuan Luo

Detecting jailbreak attempts in clinical training large language models (LLMs) requires accurate modeling of linguistic deviations that signal unsafe or off-task user behavior. Prior work on the 2-Sigma clinical simulation platform showed…

Artificial Intelligence · Computer Science 2026-02-17 Tri Nguyen , Huy Hoang Bao Le , Lohith Srikanth Pentapalli , Laurah Turner , Kelly Cohen

Objective: The objective of this study is to develop a machine learning (ML)-based framework for early risk stratification of clinical trials (CTs) according to their likelihood of exhibiting a high rate of dosing errors, using information…

Machine Learning · Computer Science 2026-02-27 Félicien Hêche , Sohrab Ferdowsi , Anthony Yazdani , Sara Sansaloni-Pastor , Douglas Teodoro

Existing text representations such as embeddings and bag-of-words are not suitable for rule learning due to their high dimensionality and absent or questionable feature-level interpretability. This article explores whether large language…

Machine Learning · Computer Science 2025-10-02 Vojtěch Balek , Lukáš Sýkora , Vilém Sklenák , Tomáš Kliegr

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Background: Data collected in controlled settings typically results in high-quality datasets. However, in real-world applications, the quality of data collection is often compromised. It is well established that the quality of a dataset…

Computation and Language · Computer Science 2025-02-14 Tabinda Sarwar , Antonio Jose Jimeno Yepes , Lawrence Cavedon

AI computation in healthcare faces significant challenges when clinical datasets are limited and heterogeneous. Integrating datasets from multiple sources and different equipments is critical for effective AI computation but is complicated…

Signal Processing · Electrical Eng. & Systems 2025-04-07 Baozhuo Su , Qingli Dou , Kang Liu , Zhengxian Qu , Jerry Deng , Ting Tan , Yanan Gu

Academic misconduct detection in biomedical research remains challenging due to algorithmic narrowness in existing methods and fragmented analytical pipelines. We present BMDetect, a multimodal deep learning framework that integrates…

Machine Learning · Computer Science 2025-07-16 Yize Zhou , Jie Zhang , Meijie Wang , Lun Yu

This study investigates the use of unsupervised word embeddings and sequence features for sample representation in an active learning framework built to extract clinical concepts from clinical free text. The objective is to further reduce…

Computation and Language · Computer Science 2016-11-16 Mahnoosh Kholghi , Lance De Vine , Laurianne Sitbon , Guido Zuccon , Anthony Nguyen

Despite the widely reported success of embedding-based machine learning methods on natural language processing tasks, the use of more easily interpreted engineered features remains common in fields such as cognitive impairment (CI)…

Machine Learning · Computer Science 2020-10-14 Benjamin Eyre , Aparna Balagopalan , Jekaterina Novikova

Programming is a core skill in computer science and software engineering (SE), yet identifying and resolving code errors remains challenging for both novice and experienced developers. While Large Language Models (LLMs) have shown…

Software Engineering · Computer Science 2026-03-27 Md Faizul Ibne Amin , Yutaka Watanobe , Md. Mostafizer Rahman , Daniel M. Muepu , Md. Shahajada Mia

It is well known that fraudulent reviews cast doubt on the legitimacy and dependability of online purchases. The most recent development that leads customers towards darkness is the appearance of human reviews in computer-generated (CG)…

Computation and Language · Computer Science 2025-12-01 Shabbir Anees , Anshuman , Ayush Chaurasia , Prathmesh Bogar

Machine learning-based multi-label medical text classifications can be used to enhance the understanding of the human body and aid the need for patient care. We present a broad study on clinical natural language processing techniques to…

Information Retrieval · Computer Science 2020-04-02 Vithya Yogarajan , Jacob Montiel , Tony Smith , Bernhard Pfahringer

Large language models (LLMs) have achieved remarkable performance on diverse benchmarks, yet existing evaluation practices largely rely on coarse summary metrics that obscure underlying reasoning abilities. In this work, we propose novel…

Methodology · Statistics 2026-03-17 Jia Liu , Zhiyu Xu , Yuqi Gu

With healthcare being critical aspect, health insurance has become an important scheme in minimizing medical expenses. Following this, the healthcare industry has seen a significant increase in fraudulent activities owing to increased…

Machine Learning · Computer Science 2022-06-29 Akrity Kumari , Narinder Singh Punn , Sanjay Kumar Sonbhadra , Sonali Agarwal
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