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Principal Component Analysis (PCA) and other multi-variate models are often used in the analysis of "omics" data. These models contain much information which is currently neither easily accessible nor interpretable. Here we present an…

Genomics · Quantitative Biology 2021-11-18 Nordine Aouni , Luc Linders , David Robinson , Len Vandelaer , Jessica Wiezorek , Geetesh Gupta , Rachel Cavill

Independent Component Analysis (ICA) is a fundamental unsupervised learning technique foruncovering latent structure in data by separating mixed signals into their independent sources. While substantial progress has been made in…

Machine Learning · Computer Science 2026-04-13 Yuwen Jiang

We present a technique to perform dimensionality reduction on data that is subject to uncertainty. Our method is a generalization of traditional principal component analysis (PCA) to multivariate probability distributions. In comparison to…

Machine Learning · Computer Science 2019-10-14 Jochen Görtler , Thilo Spinner , Dirk Streeb , Daniel Weiskopf , Oliver Deussen

We present a robust alternative to principal component analysis (PCA) --- called elliptical component analysis (ECA) --- for analyzing high dimensional, elliptically distributed data. ECA estimates the eigenspace of the covariance matrix of…

Machine Learning · Statistics 2016-10-04 Fang Han , Han Liu

The functional ANOVA expansion of a multivariate mapping plays a fundamental role in statistics. The expansion is unique once a unique distribution is assigned to the covariates. Recent investigations in the environmental and climate…

Computation · Statistics 2018-01-17 Emanuele Borgonovo , Max D. Morris , Elmar Plischke

A multi-reader multi-case (MRMC) analysis is applied to account for both reader and case variability when evaluating the clinical performance of a medical imaging device or reader performance under different reading modalities. For a…

Quantitative Methods · Quantitative Biology 2023-12-27 Si Wen , Brandon D. Gallas

The principal component analysis (PCA) of different parameters affecting collectivity of nuclei predicted to be candidate of the interacting boson model dynamical symmetries are performed. The results show that, the use of PCA within…

Nuclear Theory · Physics 2015-06-24 A. Al-Sayed

Classical methods such as Principal Component Analysis (PCA) and Canonical Correlation Analysis (CCA) are ubiquitous in statistics. However, these techniques are only able to reveal linear relationships in data. Although nonlinear variants…

Machine Learning · Statistics 2014-05-14 David Lopez-Paz , Suvrit Sra , Alex Smola , Zoubin Ghahramani , Bernhard Schölkopf

In this paper we analyze approximate methods for undertaking a principal components analysis (PCA) on large data sets. PCA is a classical dimension reduction method that involves the projection of the data onto the subspace spanned by the…

Machine Learning · Statistics 2017-08-16 Darren Homrighausen , Daniel J. McDonald

Principal component analysis (PCA) aims at estimating the direction of maximal variability of a high-dimensional dataset. A natural question is: does this task become easier, and estimation more accurate, when we exploit additional…

Information Theory · Computer Science 2014-06-19 Andrea Montanari , Emile Richard

Simultaneous variable selection and statistical inference is challenging in high-dimensional data analysis. Most existing post-selection inference methods require explicitly specified regression models, which are often linear, as well as…

Methodology · Statistics 2026-03-19 Shangyuan Ye , Shauna Rakshe , Ye Liang

Principal component analysis (PCA) is a statistical technique commonly used in multivariate data analysis. However, PCA can be difficult to interpret and explain since the principal components (PCs) are linear combinations of the original…

Mathematical Software · Computer Science 2013-12-24 W. Liu , H. Zhang , D. Tao , Y. Wang , K. Lu

A major challenge in nuclear fusion research is the coherent combination of data from heterogeneous diagnostics and modelling codes for machine control and safety as well as physics studies. Measured data from different diagnostics often…

In this paper we propose a method for the approximation of high-dimensional functions over finite intervals with respect to complete orthonormal systems of polynomials. An important tool for this is the multivariate classical analysis of…

Numerical Analysis · Mathematics 2022-01-31 Daniel Potts , Michael Schmischke

In this paper, we develop a systematic theory for high dimensional analysis of variance in multivariate linear regression, where the dimension and the number of coefficients can both grow with the sample size. We propose a new \emph{U}~type…

Methodology · Statistics 2023-01-12 Zhipeng Lou , Xianyang Zhang , Wei Biao Wu

Sparse principal component analysis (SPCA) has emerged as a powerful technique for modern data analysis, providing improved interpretation of low-rank structures by identifying localized spatial structures in the data and disambiguating…

Studies show that Studies that cardiovascular diseases (CVDs) are malignant for human health. Thus, it is important to have an efficient way of CVD prognosis. In response to this, the healthcare industry has adopted machine learning-based…

Machine Learning · Computer Science 2022-08-02 Mohammed Nowshad Ruhani Chowdhury , Wandong Zhang , Thangarajah Akilan

In fields such as ecology, microbiology, and genomics, non-Euclidean distances are widely applied to describe pairwise dissimilarity between samples. Given these pairwise distances, principal coordinates analysis (PCoA) is commonly used to…

Quantitative Methods · Quantitative Biology 2020-03-24 Yushu Shi , Liangliang Zhang , Kim-Anh Do , Christine Peterson , Robert Jenq

Principal component analysis (PCA) is one of the most popular dimension reduction techniques in statistics and is especially powerful when a multivariate distribution is concentrated near a lower-dimensional subspace. Multivariate extreme…

Methodology · Statistics 2025-07-15 Felix Reinbott , Anja Janßen

Principal component analysis (PCA) is a dimensionality reduction method in data analysis that involves diagonalizing the covariance matrix of the dataset. Recently, quantum algorithms have been formulated for PCA based on diagonalizing a…

Quantum Physics · Physics 2022-10-26 Max Hunter Gordon , M. Cerezo , Lukasz Cincio , Patrick J. Coles
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