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A wide range of methods currently exist for testing the presence of malaria, each with its own advantages and disadvantages. New technologies are urgently needed to develop more effective diagnosis tools to fight and eradicate malaria.…

Medical Physics · Physics 2025-08-26 A. S. Kiyumbi , M. S. Tame

Surface Plasmon Resonance (SPR) offers a powerful tool for label-free and non-invasive characterization of biomolecular interactions. To date, several experimental configurations, based on two fundamental physical phenomena, e.g.,…

Optics · Physics 2022-11-15 Nishant Shukla , Pawan Chetri , Ratan Boruah , Ankur Gogoi , Gazi A Ahmed

We present a simulation guided design for a multilayer surface plasmon resonance (SPR) based biosensor capable of detecting refractive index changes in a target induced by analytes. Surface plasmons are excited using a hybrid Kretschmann…

Optics · Physics 2025-12-23 R. Runthala , V. K. Venkatesh , D. Gupta , P. Arora

This paper presents a comprehensive study on a novel multilayer surface plasmon resonance (SPR) biosensor designed for detecting trace-level toxins in liquid samples with exceptional precision and efficiency. Leveraging the Kretschmann…

Systems and Control · Electrical Eng. & Systems 2025-01-31 Suripto Bhuiyan , Michael Geller

A mirrored bilayer structure incorporating layers of Graphene and MoS2 is proposed here for Surface Plasmon Resonance (SPR) biosensing and its performance is evaluated numerically. Starting from the basic configuration, the structure with…

Optics · Physics 2020-02-10 Sayeed Shafayet Chowdhury , Syed Mohammad Ashab Uddin

A broadband detection method with coherent laser pulses exciting surface plasmons is investigated. The intensity and phase characteristics of the reflected light in Kretschmann configuration are calculated. It is shown that by mixing…

Instrumentation and Detectors · Physics 2018-11-14 Alexandre Kolomenskii , Elizabeth Surovic , Hans Schuessler

This work presents a high-performance, multilayered surface plasmon resonance (SPR)-based sensor designed to enhance performance parameters in the near-infrared (NIR) region through angular interrogation. The multi-layered sensor consists…

Optics · Physics 2025-11-11 R. Runthala , N. Grover , P. Arora

Microstructure properties of Co/Au multilayers prepared using dc-magnetron sputtering is reported using X-ray reflectivity (XRR) and X-ray diffraction (XRD) analysis. XRR profiles of these multilayers showed excellent bilayer periodicity.…

Soft Condensed Matter · Physics 2021-12-07 Conrad Rizal

The measurement of in-plane birefringence ($\Delta{n}$) of ultrathin film is challenging due to a significant deviation of physical properties of materials in ultrathin regime as compared to that in bulk state. Surface plasmon resonance…

Soft Condensed Matter · Physics 2021-01-21 Amrit Kumar , Raj Kumar Gupta , V. Manjuladevi , Ashutosh Joshi

We present results from an instrument combining surface acoustic wave (SAW) propagation and surface plasmon resonance (SPR) measurements. The objective is to use two independent methods, the former based on adsorbed mass change measurements…

Soft Condensed Matter · Physics 2009-11-10 J. -M. Friedt , L. Francis , G. Reekmans , R. De Palma , A. Campitelli , U. B. Sleytr

In this paper the angular characteristics of a multimode fiber SPR sensor are theoretically investigated. By separating the contributions of beams incident at different angles, a compact model is presented to predict the shift of the…

Optics · Physics 2015-11-13 Zhixin Tan , Xin Hao , Xuejin Li , Yuzhi Chen , Xueming Hong , Ping Fan

In this study, we present a highly sensitive Surface Plasmon Resonance (SPR)-based biosensor integrated with a circular-lattice Photonic Crystal Fiber (PCF) for early-stage cancer detection. The proposed sensor leverages the synergy between…

Biosensors based on the principle of surface plasmon resonance (SPR) detection were used to measure biomolecular interactions in sarcomeres and changes of the dielectric constant of tubulin samples with varying concentration. At SPR,…

Quantum Physics · Physics 2015-06-26 Hans A. Schuessler , Alexander A. Kolomenskii , Andreas Mershin , D. V. Nanopoulos

Surface plasmon resonance (SPR) sensors built on photonic crystal fibers (PCFs) have recently become a promising category of optical sensing platforms. This is primarily due to their high sensitivity, compact structural design and ability…

Fundamental understanding of the light-matter interaction in the context of nano-particles is immensely bene- fited by the study of geometry dependent tunable Localized Surface Plasmon Resonance (LSPR) and has been demonstrated to have…

Malaria remains a major health threat in low-resource regions and rapid diagnostic tests often lack the sensitivity required for early detection. To address this and help establish more sensitive testing devices, we develop a predictive…

Optics · Physics 2026-01-15 A. S. Kiyumbi , M. S. Tame

Surface Plasmon Resonance (SPR) is an important bio-sensing technique for real-time label-free detection. However, it is pivotal to optimize various parameters of the sensor configuration for efficient and highly sensitive sensing. To that…

Biological Physics · Physics 2020-07-20 Ehsan Kabir , Syed Mohammad Ashab Uddin , Sayeed Shafayet Chowdhury

We report on a Surface-Plasmon-Resonance (SPR) technique based on Fourier -Transform - Infra - Red (FTIR) spectrometer. In contrast to the conventional surface plasmon technique, operating at a fixed wavelength and a variable angle of…

Soft Condensed Matter · Physics 2013-03-19 V. Lirtsman , M. Golosovsky , D. Davidov

Photonic crystal fiber (PCF)-based plasmonic sensors have gained considerable attention because of their highly sensitive performance and broad range of sensing regimes. In this work, a relatively simple ultra-sensitive PCF-based surface…

Surface plasmon resonance (SPR) is generally observed by excitation of surface plasmon polaritons on the metal (Au/Ag) surface. In order to utilize the SPR phenomenon for sensing application, the metal surface is functionalized with…

Optics · Physics 2022-12-20 Amrit Kumar , Manjuladevi V , R. K. Gupta
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