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Advances in Automation and Artificial Intelligence continue to enhance the autonomy of process plants in handling various operational scenarios. However, certain tasks, such as fault handling, remain challenging, as they rely heavily on…

Artificial Intelligence · Computer Science 2026-02-11 Milapji Singh Gill , Javal Vyas , Artan Markaj , Felix Gehlhoff , Mehmet Mercangöz

Digital Twin (DT) has gained great interest as an innovative technology in Industry 4.0 that enables advanced modeling, simulation, and optimization of service and manufacturing systems. This article provides an extensive review of the…

General Mathematics · Mathematics 2026-01-26 Sarow Saeedi

Automotive software increasingly outpaces hardware availability, forcing late integration and expensive hardware-in-the-loop (HiL) bottlenecks. The InnoRegioChallenge project investigated whether a virtual test and integration environment…

Software Engineering · Computer Science 2026-05-05 Sebastian Dingler , Frederik Boenke

Recently there has been a surge of interest in developing Digital Twins of process flows in healthcare to better understand bottlenecks and areas of improvement. A key challenge is in the validation process. We describe a work in progress…

Artificial Intelligence · Computer Science 2023-03-10 Muhammad Aurangzeb Ahmad , Vijay Chickarmane , Farinaz Sabz Ali Pour , Nima Shariari , Taposh Dutta Roy

A digital twin contains up-to-date data-driven models of the physical world being studied and can use simulation to optimise the physical world. However, the analysis made by the digital twin is valid and reliable only when the model is…

Artificial Intelligence · Computer Science 2024-11-01 Nan Zhang , Rami Bahsoon , Nikos Tziritas , Georgios Theodoropoulos

A quantum computing simulation provides the opportunity to explore the behaviors of quantum circuits, study the properties of quantum gates, and develop quantum computing algorithms. Simulating quantum circuits requires geometric time and…

Quantum Physics · Physics 2024-07-10 Lee A. Belfore

There is a need for remote learning and virtual learning applications such as virtual reality (VR) and tablet-based solutions which the current pandemic has demonstrated. Creating complex learning scenarios by developers is highly…

Artificial Intelligence · Computer Science 2021-06-18 Claire Palmer , Ben Roullier , Muhammad Aamir , Leonardo Stella , Uchenna Diala , Ashiq Anjum , Frank Mcquade , Keith Cox , Alex Calvert

The challenge of translating vast, multimodal biological data into predictive and mechanistic understanding of cellular function is a central theme in modern biology. Virtual cells, or digital cellular twins, have emerged as a critical…

Quantitative Methods · Quantitative Biology 2025-09-24 Saurabh Bhardwaj , Gaurav Kumar , Haochen Yang , Shaurya Bhardwaj , Qun Wang , Minjie Shen , Yizhi Wang , Cristabelle Madona De Souza

In this paper, we introduce a decentralized digital twin (DDT) framework for dynamical systems and discuss the prospects of the DDT modeling paradigm in computational science and engineering applications. The DDT approach is built on a…

Machine Learning · Computer Science 2022-07-26 Omer San , Suraj Pawar , Adil Rasheed

Network Digital Twins represent a key technology in future networks, expected to provide the capability to perform accurate analysis and predictions about the behaviour of 6G mobile networks. However, despite the availability of several…

Networking and Internet Architecture · Computer Science 2025-10-15 Cristina Emilia Costa , Tatenda Horiro Zhou , Fabrizio Granelli

We propose a \textit{guided multi-fidelity Bayesian optimization} framework for data-efficient controller tuning that integrates corrected digital twin simulations with real-world measurements. The method targets closed-loop systems with…

Robotics · Computer Science 2025-10-21 Mahdi Nobar , Jürg Keller , Alessandro Forino , John Lygeros , Alisa Rupenyan

Brain digital twins aim to provide faithful, individualized computational representations of brains as dynamical systems, enabling mechanistic understanding and supporting prediction of clinical interventions. Yet current approaches remain…

Computational Engineering, Finance, and Science · Computer Science 2026-04-16 Alexandre Muzy

With healthcare demand rising worldwide, hospital services are increasingly needed. Hospitals' performance is tightly linked to their surgical suite performance, which makes it necessary for surgical suites to be efficient. In this paper,…

Optimization and Control · Mathematics 2025-09-04 Leah Rifi , Canan Pehlivan , Cléa Martinez , Maria Di Mascolo , Franck Fontanili

Digital twins are virtual replicas of physical entities and are poised to transform personalized medicine through the real-time simulation and prediction of human physiology. Translating this paradigm from engineering to biomedicine…

The photovoltaic industry faces the challenge of optimizing the performance and management of its systems in an increasingly digitalized environment. In this context, digital twins offer an innovative solution: virtual models that replicate…

Digital twin (DT) technology has become of interest in the automotive industry. There is a growing need for smarter services that utilize the unique capabilities of DTs, ranging from computer-aided remote control to cloud-based fleet…

Robotics · Computer Science 2025-09-11 Stefan Ramdhan , Winnie Trandinh , Istvan David , Vera Pantelic , Mark Lawford

This paper presents a digital-twin platform for active safety analysis in mixed traffic environments. The platform is built using a multi-modal data-enabled traffic environment constructed from drone-based aerial LiDAR, OpenStreetMap, and…

Robotics · Computer Science 2025-04-28 Hao Zhang , Ximin Yue , Kexin Tian , Sixu Li , Keshu Wu , Zihao Li , Dominique Lord , Yang Zhou

Creating a digital world that closely mimics the real world with its many complex interactions and outcomes is possible today through advanced emulation software and ubiquitous computing power. Such a software-based emulation of an entity…

Signal Processing · Electrical Eng. & Systems 2023-05-18 Batool Salehi , Utku Demir , Debashri Roy , Suyash Pradhan , Jennifer Dy , Stratis Ioannidis , Kaushik Chowdhury

The concept of the Digital Twin, which in the context of this paper is the virtual representation of a production system or its components, can be used as a "digital playground" to master the increasing complexity of these assets. One of…

Computational Engineering, Finance, and Science · Computer Science 2024-10-15 Daniel Dittler , Valentin Stegmaier , Nasser Jazdi , Michael Weyrich

We present methods and applications for the development of digital twins (DT) for urban traffic management. While the majority of studies on the DT focus on its ``eyes," which is the emerging sensing and perception like object detection and…

Systems and Control · Electrical Eng. & Systems 2026-02-05 Yongjie Fu , Mehmet K. Turkcan , Mahshid Ghasemi , Zhaobin Mo , Chengbo Zang , Abhishek Adhikari , Zoran Kostic , Gil Zussman , Xuan Di
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