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An electron-tracking Compton camera (ETCC) is a detector that can determine the arrival direction and energy of incident sub-MeV/MeV gamma-ray events on an event-by-event basis. It is a hybrid detector consisting of a gaseous time…

Cryo-electron tomography (cryo-ET) has emerged as a powerful tool for studying the structural heterogeneity of proteins and their complexes, offering insights into macromolecular dynamics directly within cells. Driven by recent…

Biomolecules · Quantitative Biology 2025-07-01 Jackson Carrion , Joseph H. Davis

Spectroscopy requires high-precision wavelength discrimination but typically requires bulky, alignment-sensitive instrumentation. To address this, we present a compact computational spectrometer built from a single germanium PN photodiode.…

Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…

Medical Physics · Physics 2016-08-01 Lei Li , Ailong Cai , Linyuan Wang , Bin Yan , Hanming Zhang , Zhizhong Zheng , Wenkun Zhang , Wanli Lu , Guoen Hu

In this paper we demonstrate the utility of fusing energy-resolved observations of Compton scattered photons with traditional attenuation data for the joint recovery of mass density and photoelectric absorption in the context of limited…

Computer Vision and Pattern Recognition · Computer Science 2017-07-07 Hamideh Rezaee , Brian Tracey , Eric L. Miller

Riptide is a detector concept aiming to track fast neutrons. It is based on neutron--proton elastic collisions inside a plastic scintillator, where the neutron momentum can be measured by imaging the scintillation light. More specifically,…

Electron tomography has achieved higher resolution and quality at reduced doses with recent advances in compressed sensing. Compressed sensing (CS) theory exploits the inherent sparse signal structure to efficiently reconstruct…

Computational Physics · Physics 2020-12-02 Jonathan Schwartz , Huihuo Zheng , Marcus Hanwell , Yi Jiang , Robert Hovden

Electron tomography is becoming an increasingly important tool in materials science for studying the three-dimensional morphologies and chemical compositions of nanostructures. The image quality obtained by many current algorithms is…

Three-dimensional (3D) reconstruction of head Computed Tomography (CT) images elucidates the intricate spatial relationships of tissue structures, thereby assisting in accurate diagnosis. Nonetheless, securing an optimal head CT scan…

Computer Vision and Pattern Recognition · Computer Science 2023-09-18 Bowen Zheng , Chenxi Huang , Yuemei Luo

We present an alternative numerical reconstruction algorithm for direct tomographic reconstruction of a sample refractive indices from the measured intensities of its far-field coherent diffraction patterns. We formulate the well-known…

Computational Physics · Physics 2019-02-06 T. Ramos , Bastian E. Grønager , Martin Skovgaard Andersen , J. W. Andreasen

We report the development of deep learning coherent electron diffractive imaging at sub-angstrom resolution using convolutional neural networks (CNNs) trained with only simulated data. We experimentally demonstrate this method by applying…

Materials Science · Physics 2022-04-19 Dillan J. Chang , Colum M. O'Leary , Cong Su , Salman Kahn , Alex Zettl , Jim Ciston , Peter Ercius , Jianwei Miao

As a burgeoning technique, out-of-focus electron ptychography offers the potential for rapidly imaging atomic-scale large fields of view (FoV) using a single diffraction dataset. However, achieving robust out-of-focus ptychographic…

Single particle cryo-electron microscopy is a vital tool for 3D characterization of protein structures. A typical workflow involves acquiring projection images of a collection of randomly oriented particles, picking and classifying…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 S. V. Venkatakrishnan , Puneet Juneja , Hugh O'Neill

We have developed a neural network model to perform event reconstruction of Compton telescopes. This model reconstructs events that consist of three or more interactions in a detector. It is essential for Compton telescopes to determine the…

Instrumentation and Methods for Astrophysics · Physics 2022-06-22 Satoshi Takashima , Hirokazu Odaka , Hiroki Yoneda , Yuto Ichinohe , Aya Bamba , Tsuguo Aramaki , Yoshiyuki Inoue

A new technique for medical imaging, "3{\gamma} imaging", is studied by our group at SUBATECH for few years. A small liquid xenon time projection chamber prototype has been built in order to demonstrate the feasibility of this technique.…

Measuring dark matter (DM) signals via electron recoil provides an important means for direct detection of light DM particles. The recent XENON1T anomaly with electron recoil energy around $\,E_R^{}\!=\!(2-3)$keV can be naturally explained…

High Energy Physics - Phenomenology · Physics 2021-01-26 Hong-Jian He , Yu-Chen Wang , Jiaming Zheng

We propose a method to reconstruct the 3-D molecular structure from micrographs collected at just one sample tilt angle in the random conical tilt scheme in cryo-electron microscopy. Our method uses autocorrelation analysis on the…

Data Analysis, Statistics and Probability · Physics 2021-01-12 Ti-Yen Lan , Nicolas Boumal , Amit Singer

We experimentally demonstrate a method for reconstructing the transverse 4D phase space of an electron beam at the time of emission from downstream diagnostics of the 4D phase space. This method does not rely on detailed knowledge of the…

Three-dimensional track reconstruction is a key issue for directional Dark Matter detection. It requires a precise knowledge of the electron drift velocity. Magboltz simulations are known to give a good evaluation of this parameter.…

Instrumentation and Methods for Astrophysics · Physics 2014-01-07 F. Mayet , J. Billard , G. Bosson , O. Bourrion , O. Guillaudin , J. Lamblin , J. P. Richer , Q. Riffard , D. Santos , F. J. Iguaz , L. Lebreton , D. Maire

A prototype detector for Compton camera imaging is under development. A monolithic array of 19 channel Silicon drift detector with on-chip electronics is going to be used as a scatter detector for the prototype system. Custom designed…

Instrumentation and Detectors · Physics 2009-11-10 T. Conka Nurdan , K. Nurdan , A. H. Walenta , H. J. Besch , C. Fiorini , B. Freisleben , N. A. Pavel
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