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In multi-organ segmentation of abdominal CT scans, most existing fully supervised deep learning algorithms require lots of voxel-wise annotations, which are usually difficult, expensive, and slow to obtain. In comparison, massive unlabeled…

Computer Vision and Pattern Recognition · Computer Science 2018-11-21 Yuyin Zhou , Yan Wang , Peng Tang , Song Bai , Wei Shen , Elliot K. Fishman , Alan L. Yuille

We propose a novel approach to translate unpaired contrast computed tomography (CT) scans to non-contrast CT scans and the other way around. Solving this task has two important applications: (i) to automatically generate contrast CT scans…

Transfer learning has gained attention in medical image analysis due to limited annotated 3D medical datasets for training data-driven deep learning models in the real world. Existing 3D-based methods have transferred the pre-trained models…

Computer Vision and Pattern Recognition · Computer Science 2021-04-29 Eunji Jun , Seungwoo Jeong , Da-Woon Heo , Heung-Il Suk

Foundation segmentation models such as the Segment Anything Model (SAM) have demonstrated strong generalization across natural images; however, their robustness under clinically realistic medical imaging domain shifts remains insufficiently…

Image and Video Processing · Electrical Eng. & Systems 2026-04-29 Sanghati Basu

DCE-MRI provides information about vascular permeability and tissue perfusion through the acquisition of pharmacokinetic parameters. However, traditional methods for estimating these pharmacokinetic parameters involve fitting tracer kinetic…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Gyutaek Oh , Won-Jin Moon , Jong Chul Ye

Automated segmentation of Cardiac Magnetic Resonance (CMR) plays a pivotal role in efficiently assessing cardiac function, offering rapid clinical evaluations that benefit both healthcare practitioners and patients. While recent research…

Image and Video Processing · Electrical Eng. & Systems 2024-06-14 Abdul Qayyum , Hao Xu , Brian P. Halliday , Cristobal Rodero , Christopher W. Lanyon , Richard D. Wilkinson , Steven Alexander Niederer

Purposes: This study aimed to develop a computed tomography (CT)-based multi-organ segmentation model for delineating organs-at-risk (OARs) in pediatric upper abdominal tumors and evaluate its robustness across multiple datasets. Materials…

Pancreatic tumor segmentation in contrast-enhanced computed tomography (CT) is clinically important yet technically challenging: lesions are often small, heterogeneous, and easily confused with surrounding soft tissue, and models that…

Quantitative Methods · Quantitative Biology 2026-04-24 Sunny Joy Ma , Xiang Ma

Occlusion, where target structures are partially hidden by surgical instruments or overlapping tissues, remains a critical yet underexplored challenge for foundation segmentation models in clinical endoscopy. We introduce OccSAM-Bench, a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Nhan Ho , Luu Le , Thanh-Huy Nguyen , Thien Nguyen , Xiaofeng Liu , Ulas Bagci

Deep learning (DL) applied to breast tissue segmentation in magnetic resonance imaging (MRI) has received increased attention in the last decade, however, the domain shift which arises from different vendors, acquisition protocols, and…

Accurate and reproducible brain morphometry from structural MRI is critical for monitoring neuroanatomical changes across time and across imaging domains. Although deep learning has accelerated segmentation workflows, scanner-induced…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Ekaterina Kondrateva , Sandzhi Barg , Mikhail Vasiliev

Computer aided pathological analysis has been the gold standard for tumor diagnosis, however domain shift is a significant problem in histopathology. It may be caused by variability in anatomical structures, tissue preparation, and imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Abdul Qayyum , Moona Mazher Imran Razzak , Steven A Niederer

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Quantitative cancer image analysis relies on the accurate delineation of tumours, a very specialised and time-consuming task. For this reason, methods for automated segmentation of tumours in medical imaging have been extensively developed…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Saúl Alonso-Monsalve , Leigh H. Whitehead , Adam Aurisano , Lorena Escudero Sanchez

Purpose: To develop and evaluate a deep learning model for multi-organ segmentation of MRI scans. Materials and Methods: The model was trained on 1,200 manually annotated 3D axial MRI scans from the UK Biobank, 221 in-house MRI scans, and…

Accurate automatic segmentation of brain anatomy from $T_1$-weighted~($T_1$-w) magnetic resonance images~(MRI) has been a computationally intensive bottleneck in neuroimaging pipelines, with state-of-the-art results obtained by unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Amod Jog , Bruce Fischl

A single biomedical image can be meaningfully segmented in multiple ways, depending on the desired application. For instance, a brain MRI can be segmented according to tissue types, vascular territories, broad anatomical regions,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Marianne Rakic , Siyu Gai , Etienne Chollet , John V. Guttag , Adrian V. Dalca

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

Coronary microvascular disease constitutes a substantial risk to human health. Employing computer-aided analysis and diagnostic systems, medical professionals can intervene early in disease progression, with 3D vessel segmentation serving…

Image and Video Processing · Electrical Eng. & Systems 2024-01-15 Xinyuan Wang , Chengwei Pan , Hongming Dai , Gangming Zhao , Jinpeng Li , Xiao Zhang , Yizhou Yu

Medical image segmentation is a relevant task as it serves as the first step for several diagnosis processes, thus it is indispensable in clinical usage. Whilst major success has been reported using supervised techniques, they assume a…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Lihao Liu , Angelica I Aviles-Rivero , Carola-Bibiane Schönlieb