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Cancer is a complex disease that is characterized by uncontrolled growth and division of cells. It involves a complex interplay between genetic and environmental factors that lead to the initiation and progression of tumors. Recent advances…

Biomolecules · Quantitative Biology 2025-02-07 Reza Bozorgpour

End-to-end learning has become a widely applicable and studied problem in training predictive ML models to be aware of their impact on downstream decision-making tasks. These end-to-end models often outperform traditional methods that…

Machine Learning · Computer Science 2025-05-19 Rares Cristian , Pavithra Harsha , Georgia Perakis , Brian Quanz

Control and planning of multi-agent systems is an active and increasingly studied topic of research, with many practical applications such as rescue missions, security, surveillance, and transportation. This thesis addresses the planning…

Systems and Control · Electrical Eng. & Systems 2023-03-03 Christos Verginis

Systematic exploration of Agent-Based Models (ABMs) is challenged by the curse of dimensionality and their inherent stochasticity. We present a multi-stage pipeline integrating the systematic design of experiments with machine learning…

Machine Learning · Computer Science 2026-04-07 Paul Saves , Matthieu Mastio , Nicolas Verstaevel , Benoit Gaudou

With the rapid development of artificial intelligence, intelligent decision-making techniques have gradually surpassed human levels in various human-machine competitions, especially in complex multi-agent cooperative task scenarios.…

Multiagent Systems · Computer Science 2025-03-18 Weiqiang Jin , Hongyang Du , Biao Zhao , Xingwu Tian , Bohang Shi , Guang Yang

The development of artificial intelligence systems is transitioning from creating static, task-specific models to dynamic, agent-based systems capable of performing well in a wide range of applications. We propose an Interactive Agent…

Large language models(LLMs) are now used to power complex multi-turn agentic workflows. Existing systems run agentic inference by loosely assembling isolated components: an LLM inference engine (e.g., vLLM) and a tool orchestrator (e.g.,…

Operating Systems · Computer Science 2026-03-12 Hao Kang , Ziyang Li , Xinyu Yang , Weili Xu , Yinfang Chen , Junxiong Wang , Beidi Chen , Tushar Krishna , Chenfeng Xu , Simran Arora

Molecular communication (MC) provides a foundational framework for information transmission in the Internet of Bio-Nano Things (IoBNT), where efficiency and reliability are crucial. However, the inherent limitations of molecular channels,…

Signal Processing · Electrical Eng. & Systems 2025-04-02 Hanlin Cai , Ozgur B. Akan

The complex interaction between social behaviors and climate change requires more than traditional data-driven prediction; it demands interpretable and adaptive analytical frameworks capable of integrating heterogeneous sources of…

Multiagent Systems · Computer Science 2026-03-17 Shan Shan

Accurate prediction of energy and forces for 3D molecular systems is one of fundamental challenges at the core of AI for Science applications. Many powerful and data-efficient neural networks predict molecular energies and forces from…

Chemical Physics · Physics 2026-04-23 Ali Mollahosseini , Mohammed Haroon Dupty , Wee Sun Lee

Differential Diagnosis (DDx) is a fundamental yet complex aspect of clinical decision-making, in which physicians iteratively refine a ranked list of possible diseases based on symptoms, antecedents, and medical knowledge. While recent…

Computation and Language · Computer Science 2025-06-16 Daniel Rose , Chia-Chien Hung , Marco Lepri , Israa Alqassem , Kiril Gashteovski , Carolin Lawrence

Molecular mechanics (MM) potentials have long been a workhorse of computational chemistry. Leveraging accuracy and speed, these functional forms find use in a wide variety of applications in biomolecular modeling and drug discovery, from…

Molecular dynamics simulations hold great promise for providing insight into the microscopic behavior of complex molecular systems. However, their effectiveness is often constrained by long timescales associated with rare events. Enhanced…

Computational Physics · Physics 2026-03-03 Kai Zhu , Enrico Trizio , Jintu Zhang , Renling Hu , Linlong Jiang , Tingjun Hou , Luigi Bonati

Current end-to-end multi-modal models utilize different encoders and decoders to process input and output information. This separation hinders the joint representation learning of various modalities. To unify multi-modal processing, we…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Chunhao Lu , Qiang Lu , Meichen Dong , Jake Luo

MD-GAN is a machine learning-based method that can evolve part of the system at any time step, accelerating the generation of molecular dynamics data. For the accurate prediction of MD-GAN, sufficient information on the dynamics of a part…

Chemical Physics · Physics 2022-02-03 Ryo Kawada , Katsuhiro Endo , Daisuke Yuhara , Kenji Yasuoka

The core challenge in automotive exterior design is balancing subjective aesthetics with objective aerodynamic performance while dramatically accelerating the development cycle. To address this, we propose a novel, LLM-driven multi-agent…

Computational Engineering, Finance, and Science · Computer Science 2025-08-06 Xinyu Jin , Shengmao Yan , Qingtao Wang , Shisong Deng , Yanzhen Jiang , Shuangyao Zhao

We propose Cormorant, a rotationally covariant neural network architecture for learning the behavior and properties of complex many-body physical systems. We apply these networks to molecular systems with two goals: learning atomic…

Computational Physics · Physics 2019-11-27 Brandon Anderson , Truong-Son Hy , Risi Kondor

Multiconfiguration pair-density functional theory (MC-PDFT) offers an efficient and accurate framework for computing electronic energies in strongly correlated molecular systems, with the quality of the on-top functional being a key…

Chemical Physics · Physics 2026-05-08 Yuhao Chen , Donald G. Truhlar , Xiao He

In this paper a deep reinforcement based multi-agent path planning approach is introduced. The experiments are realized in a simulation environment and in this environment different multi-agent path planning problems are produced. The…

Machine Learning · Computer Science 2021-10-05 Mert Çetinkaya

Agent-based modeling and simulation is a useful method to study biological phenomena in a wide range of fields, from molecular biology to ecology. Since there is currently no agreed-upon standard way to specify such models it is not always…

Quantitative Methods · Quantitative Biology 2010-10-14 Franziska Hinkelmann , David Murrugarra , Abdul Salam Jarrah , Reinhard Laubenbacher