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In digital pathology, different staining procedures and scanners cause substantial color variations in whole-slide images (WSIs), especially across different laboratories. These color shifts result in a poor generalization of deep…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Sophia J. Wagner , Nadieh Khalili , Raghav Sharma , Melanie Boxberg , Carsten Marr , Walter de Back , Tingying Peng

Domain shift in digital histopathology can occur when different stains or scanners are used, during stain translation, etc. A deep neural network trained on source data may not generalise well to data that has undergone some domain shift.…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Zeeshan Nisar , Jelica Vasiljević , Pierre Gançarski , Thomas Lampert

Domain shift is a problem commonly encountered when developing automated histopathology pipelines. The performance of machine learning models such as convolutional neural networks within automated histopathology pipelines is often…

Image and Video Processing · Electrical Eng. & Systems 2021-07-16 Andrew Moyes , Richard Gault , Kun Zhang , Ji Ming , Danny Crookes , Jing Wang

We cast the problem of image denoising as a domain translation problem between high and low noise domains. By modifying the cycleGAN model, we are able to learn a mapping between these domains on unpaired retinal optical coherence…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Ilja Manakov , Markus Rohm , Christoph Kern , Benedikt Schworm , Karsten Kortuem , Volker Tresp

Accurate and fast histological staining is crucial in histopathology, impacting diagnostic precision and reliability. Traditional staining methods are time-consuming and subjective, causing delays in diagnosis. Digital pathology plays a…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Marian Boktor , James E. D. Tweel , Benjamin R. Ecclestone , Jennifer Ai Ye , Paul Fieguth , Parsin Haji Reza

Despite that deep learning has achieved state-of-the-art performance for medical image segmentation, its success relies on a large set of manually annotated images for training that are expensive to acquire. In this paper, we propose an…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Lu Wang , Dong Guo , Guotai Wang , Shaoting Zhang

Blood cell identification is critical for hematological analysis as it aids physicians in diagnosing various blood-related diseases. In real-world scenarios, blood cell image datasets often present the issues of domain shift and data…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Yongcheng Li , Lingcong Cai , Ying Lu , Xianghua Fu , Xiao Han , Ma Li , Wenxing Lai , Xiangzhong Zhang , Xiaomao Fan

In this work, we study the problem of training deep networks for semantic image segmentation using only a fraction of annotated images, which may significantly reduce human annotation efforts. Particularly, we propose a strategy that…

Computer Vision and Pattern Recognition · Computer Science 2019-09-02 Arnab Kumar Mondal , Aniket Agarwal , Jose Dolz , Christian Desrosiers

Multi-domain image-to-image translation is a problem where the goal is to learn mappings among multiple domains. This problem is challenging in terms of scalability because it requires the learning of numerous mappings, the number of which…

Computer Vision and Pattern Recognition · Computer Science 2019-05-07 Takuhiro Kaneko , Tatsuya Harada

We propose a novel method that combines CycleGAN and inter-domain losses for semi-supervised end-to-end automatic speech recognition. Inter-domain loss targets the extraction of an intermediate shared representation of speech and text…

Computation and Language · Computer Science 2022-10-24 Chia-Yu Li , Ngoc Thang Vu

Recently, CycleGAN was shown to provide high-performance, ultra-fast denoising for low-dose X-ray computed tomography (CT) without the need for a paired training dataset. Although this was possible thanks to cycle consistency, CycleGAN…

Image and Video Processing · Electrical Eng. & Systems 2021-04-20 Taesung Kwon , Jong Chul Ye

Medical Image Segmentation is a useful application for medical image analysis including detecting diseases and abnormalities in imaging modalities such as MRI, CT etc. Deep learning has proven to be promising for this task but usually has a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Soham Bhosale , Arjun Krishna , Ge Wang , Klaus Mueller

Histopathological cancer diagnosis is based on visual examination of stained tissue slides. Hematoxylin and eosin (H\&E) is a standard stain routinely employed worldwide. It is easy to acquire and cost effective, but cells and tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Zhaoyang Xu , Xingru Huang , Carlos Fernández Moro , Béla Bozóky , Qianni Zhang

The presence of domain shift in medical imaging is a common issue, which can greatly impact the performance of segmentation models when dealing with unseen image domains. Adversarial-based deep learning models, such as Cycle-GAN, have…

Image and Video Processing · Electrical Eng. & Systems 2023-04-19 Paolo Iacono , Naimul Khan

Recently, deep learning approaches have been extensively studied for low-dose CT denoising thanks to its superior performance despite the fast computational time. In particular, cycleGAN has been demonstrated as a powerful unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2020-08-14 Jawook Gu , Jong Chul Ye

Recently, the cycle-consistent generative adversarial networks (CycleGAN) has been widely used for synthesis of multi-domain medical images. The domain-specific nonlinear deformations captured by CycleGAN make the synthesized images…

Computer Vision and Pattern Recognition · Computer Science 2018-08-14 Chengjia Wang , Gillian Macnaught , Giorgos Papanastasiou , Tom MacGillivray , David Newby

Accurate gland segmentation in histopathology images is essential for cancer diagnosis and prognosis. However, significant variability in Hematoxylin and Eosin (H&E) staining and tissue morphology, combined with limited annotated data,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Ha-Hieu Pham , Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Ulas Bagci , Min Xu , Trung-Nghia Le , Huy-Hieu Pham

Limited amount of labelled training data are a common problem in medical imaging. This makes it difficult to train a well-generalised model and therefore often leads to failure in unknown domains. Hippocampus segmentation from magnetic…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 John Kalkhof , Camila González , Anirban Mukhopadhyay

The analysis of the tumor environment on digital histopathology slides is becoming key for the understanding of the immune response against cancer, supporting the development of novel immuno-therapies. We introduce here a novel deep…

Image and Video Processing · Electrical Eng. & Systems 2019-06-27 Ansh Kapil , Tobias Wiestler , Simon Lanzmich , Abraham Silva , Keith Steele , Marlon Rebelatto , Guenter Schmidt , Nicolas Brieu

Instance segmentation for unlabeled imaging modalities is a challenging but essential task as collecting expert annotation can be expensive and time-consuming. Existing works segment a new modality by either deploying a pre-trained model…

Computer Vision and Pattern Recognition · Computer Science 2022-04-08 Leander Lauenburg , Zudi Lin , Ruihan Zhang , Márcia dos Santos , Siyu Huang , Ignacio Arganda-Carreras , Edward S. Boyden , Hanspeter Pfister , Donglai Wei