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The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

Multiple myeloma is managed through sequential lines of therapy over years to decades, with each decision depending on cumulative disease history distributed across dozens to hundreds of heterogeneous clinical documents. Whether LLM-based…

Large language models (LLMs) are increasingly applied in biomedical domains, yet their reliability in drug-safety prediction remains underexplored. In this work, we investigate whether LLMs incorporate socio-demographic information into…

Computation and Language · Computer Science 2025-10-17 Siying Liu , Shisheng Zhang , Indu Bala

The integration of Large Language Models (LLMs) into healthcare is constrained by knowledge limitations, hallucinations, and a disconnect from Evidence-Based Medicine (EBM). While Retrieval-Augmented Generation (RAG) offers a solution,…

Computation and Language · Computer Science 2026-02-03 Qiaoyu Zheng , Yuze Sun , Chaoyi Wu , Weike Zhao , Pengcheng Qiu , Yongguo Yu , Kun Sun , Jian Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

Recent advancements in Large Language Models(LLMs) have been notable, yet widespread enterprise adoption remains limited due to various constraints. This paper examines bias in LLMs-a crucial issue affecting their usability, reliability,…

Artificial Intelligence · Computer Science 2026-05-28 Vishal Mirza , Rahul Kulkarni , Aakanksha Jadhav

Large Language Models (LLMs) have excelled at language understanding and generating human-level text. However, even with supervised training and human alignment, these LLMs are susceptible to adversarial attacks where malicious users can…

Computation and Language · Computer Science 2024-08-08 Shachi H Kumar , Saurav Sahay , Sahisnu Mazumder , Eda Okur , Ramesh Manuvinakurike , Nicole Beckage , Hsuan Su , Hung-yi Lee , Lama Nachman

Large language models (LLMs) are the foundation of the current successes of artificial intelligence (AI), however, they are unavoidably biased. To effectively communicate the risks and encourage mitigation efforts these models need adequate…

Computation and Language · Computer Science 2025-01-14 Carolin M. Schuster , Maria-Alexandra Dinisor , Shashwat Ghatiwala , Georg Groh

Foundation models, including large language models (LLMs) and vision-language models (VLMs), have recently enabled novel approaches to robot autonomy and human-robot interfaces. In parallel, vision-language-action models (VLAs) or large…

Large language models (LLMs) are increasingly deployed as agents, expected to decompose goals, invoke tools, and verify results in dynamic environments. Realizing these capabilities requires access to agentic data-structured interaction…

Artificial Intelligence · Computer Science 2025-10-22 Abhigya Verma , Seganrasan Subramanian , Nandhakumar Kandasamy , Naman Gupta

Large Language Models (LLMs) show promise as data analysis agents, but existing benchmarks overlook the iterative nature of the field, where experts' decisions evolve with deeper insights of the dataset. To address this, we introduce…

Computation and Language · Computer Science 2025-06-09 Hanyu Li , Haoyu Liu , Tingyu Zhu , Tianyu Guo , Zeyu Zheng , Xiaotie Deng , Michael I. Jordan

With the rapid advancement of Artificial Intelligence (AI), Large Language Models (LLMs) have significantly impacted a wide array of domains, including healthcare, engineering, science, education, and mathematical reasoning. Among these,…

Machine Learning · Computer Science 2025-05-20 Afrar Jahin , Arif Hassan Zidan , Wei Zhang , Yu Bao , Tianming Liu

Large language models and autonomous AI agents have evolved rapidly, resulting in a diverse array of evaluation benchmarks, frameworks, and collaboration protocols. Driven by the growing need for standardized evaluation and integration, we…

Artificial Intelligence · Computer Science 2026-03-10 Mohamed Amine Ferrag , Norbert Tihanyi , Merouane Debbah

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

Large Reasoning Models (LRMs) like o3 and DeepSeek-R1 have achieved remarkable progress in reasoning tasks with long cot. However, they remain computationally inefficient and struggle with accuracy when solving problems requiring complex…

Artificial Intelligence · Computer Science 2026-03-03 Haipeng Luo , Huawen Feng , Qingfeng Sun , Can Xu , Kai Zheng , Yufei Wang , Tao Yang , Han Hu , Yansong Tang

Large language models (LLMs) often reflect real-world biases, leading to efforts to mitigate these effects and make the models unbiased. Achieving this goal requires defining clear criteria for an unbiased state, with any deviation from…

Computation and Language · Computer Science 2024-11-27 Changgeon Ko , Jisu Shin , Hoyun Song , Jeongyeon Seo , Jong C. Park

Large language models (LLMs) increasingly mediate decisions in domains where unfair treatment of demographic groups is unacceptable. Existing work probes when biased outputs appear, but gives little insight into the mechanisms that generate…

Computation and Language · Computer Science 2025-11-04 Tingxu Han , Wei Song , Ziqi Ding , Ziming Li , Chunrong Fang , Yuekang Li , Dongfang Liu , Zhenyu Chen , Zhenting Wang

Large language models (LLMs) have enabled a range of applications in zero-shot and few-shot learning settings, including the generation of synthetic datasets for training and testing. However, to reliably use these synthetic datasets, it is…

Computation and Language · Computer Science 2024-09-19 Gaurav Maheshwari , Dmitry Ivanov , Kevin El Haddad

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Large Language Models (LLMs), such as GPT-4, have demonstrated impressive mathematical reasoning capabilities, achieving near-perfect performance on benchmarks like GSM8K. However, their application in personalized education remains limited…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Yi-Fan Zhang , Hang Li , Dingjie Song , Lichao Sun , Tianlong Xu , Qingsong Wen

Agentic systems are becoming more capable: agents define strategies, take actions, and interact with different environments. This autonomy poses serious challenges for overseeing and assessing agent behavior. Most current tools are limited,…

Computation and Language · Computer Science 2026-05-22 Asaf Yehudai , Lilach Eden , Michal Shmueli-Scheuer
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