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Multimodal large language models (MLLMs) represent an evolutionary expansion in the capabilities of traditional large language models, enabling them to tackle challenges that surpass the scope of purely text-based applications. It leverages…

Computation and Language · Computer Science 2025-01-17 Jinlong He , Pengfei Li , Gang Liu , Genrong He , Zhaolin Chen , Shenjun Zhong

Recently, Large Language Models~(LLMs) such as ChatGPT have showcased remarkable abilities in solving general tasks, demonstrating the potential for applications in recommender systems. To assess how effectively LLMs can be used in…

Information Retrieval · Computer Science 2025-01-17 Lanling Xu , Junjie Zhang , Bingqian Li , Jinpeng Wang , Sheng Chen , Wayne Xin Zhao , Ji-Rong Wen

There is increasing interest in the application large language models (LLMs) to the medical field, in part because of their impressive performance on medical exam questions. While promising, exam questions do not reflect the complexity of…

The dream of achieving a student-teacher ratio of 1:1 is closer than ever thanks to the emergence of large language models (LLMs). One potential application of these models in the educational field would be to provide feedback to students…

Computers and Society · Computer Science 2025-05-06 Marc Ballestero-Ribó , Daniel Ortiz-Martínez

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Previous learning-based vulnerability detection methods relied on either medium-sized pre-trained models or smaller neural networks from scratch. Recent advancements in Large Pre-Trained Language Models (LLMs) have showcased remarkable…

Software Engineering · Computer Science 2024-01-30 Xin Zhou , Ting Zhang , David Lo

The integration of Large Language Models (LLMs) like GPT-4o into robotic systems represents a significant advancement in embodied artificial intelligence. These models can process multi-modal prompts, enabling them to generate more…

Robotics · Computer Science 2024-09-10 Wenxiao Zhang , Xiangrui Kong , Conan Dewitt , Thomas Braunl , Jin B. Hong

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Recent researches of large language models(LLM), which is pre-trained on massive general-purpose corpora, have achieved breakthroughs in responding human queries. However, these methods face challenges including limited data insufficiency…

Computation and Language · Computer Science 2025-01-07 Yiming Zhang , Zheng Chang , Wentao Cai , MengXing Ren , Kang Yuan , Yining Sun , Zenghui Ding

Objective: Clinical trials are essential for advancing pharmaceutical interventions, but they face a bottleneck in selecting eligible participants. Although leveraging electronic health records (EHR) for recruitment has gained popularity,…

Computation and Language · Computer Science 2026-01-15 Mojdeh Rahmanian , Seyed Mostafa Fakhrahmad , Seyedeh Zahra Mousavi

The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…

Machine Learning · Computer Science 2026-04-07 Yaxin Xu , Yue Zhou , Tianyu Zhao , Fengwei An , Zhixiang Ren

The overwhelming success of GPT-4 in early 2023 highlighted the transformative potential of large language models (LLMs) across various sectors, including national security. This article explores the implications of LLM integration within…

Cryptography and Security · Computer Science 2024-07-08 William N. Caballero , Phillip R. Jenkins

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

Large language models (LLMs) such as ChatGPT have gained considerable interest across diverse research communities. Their notable ability for text completion and generation has inaugurated a novel paradigm for language-interfaced problem…

Quantitative Methods · Quantitative Biology 2024-02-22 Hengchuang Yin , Zhonghui Gu , Fanhao Wang , Yiparemu Abuduhaibaier , Yanqiao Zhu , Xinming Tu , Xian-Sheng Hua , Xiao Luo , Yizhou Sun

Patient experience and care quality are crucial for a hospital's sustainability and reputation. The analysis of patient feedback offers valuable insight into patient satisfaction and outcomes. However, the unstructured nature of these…

Computation and Language · Computer Science 2025-02-21 Hajar Sakai , Sarah S. Lam , Mohammadsadegh Mikaeili , Joshua Bosire , Franziska Jovin

Background and Aims: This study evaluates the medical reasoning performance of large language models (LLMs) and vision language models (VLMs) in gastroenterology. Methods: We used 300 gastroenterology board exam-style multiple-choice…

We evaluate four state-of-the-art instruction-tuned large language models (LLMs) -- ChatGPT, Flan-T5 UL2, Tk-Instruct, and Alpaca -- on a set of 13 real-world clinical and biomedical natural language processing (NLP) tasks in English, such…

Computation and Language · Computer Science 2024-06-11 Yanis Labrak , Mickael Rouvier , Richard Dufour

In this paper, we explore the challenges inherent to Large Language Models (LLMs) like GPT-4, particularly their propensity for hallucinations, logic mistakes, and incorrect conclusions when tasked with answering complex questions. The…

Computation and Language · Computer Science 2023-12-22 Xiang Li , Haoran Tang , Siyu Chen , Ziwei Wang , Anurag Maravi , Marcin Abram

Coreference resolution in biomedical texts presents unique challenges due to complex domain-specific terminology, high ambiguity in mention forms, and long-distance dependencies between coreferring expressions. In this work, we present a…

Computation and Language · Computer Science 2025-10-30 Nourah M Salem , Elizabeth White , Michael Bada , Lawrence Hunter
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