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Cloud-accessible quantum processors enable direct execution of quantum algorithms on heterogeneous hardware platforms. Unlike classical systems, however, identical quantum circuits may exhibit substantially different behavior across devices…

Quantum Physics · Physics 2026-01-12 Askar Oralkhan , Temirlan Zhaxalykov

A clustered adaptive intervention (cAI) is a pre-specified sequence of decision rules that guides practitioners on how best - and based on which measures - to tailor cluster-level intervention to improve outcomes at the level of individuals…

Methodology · Statistics 2025-05-05 Yao Song , Kelly Speth , Amy Kilbourne , Andrew Quanbeck , Daniel Almirall , Lu Wang

Quantum computing has gained a lot of attention recently, and scientists have seen potential applications in this field using quantum computing for Cryptography and Communication to Machine Learning and Healthcare. Protein folding has been…

Quantum Physics · Physics 2022-11-16 Hasan Mustafa , Sai Nandan Morapakula , Prateek Jain , Srinjoy Ganguly

Molecular ground-state simulation is one of the most promising fields for demonstrating practical quantum advantage on near-term quantum computers. However, the Variational Quantum Eigensolver (VQE), a leading algorithm for this task, still…

Quantum Physics · Physics 2025-07-08 Runhong He , Qiaozhen Chai , Xin Hong , Ji Guan , Guolong Cui , Shengbin Wang , Shenggang Ying

In this paper, we have developed a unitary variant of a double exponential coupled cluster theory, which is capable of mimicking the effects of connected excitations of arbitrarily high rank, using only rank-one and rank-two parametrization…

Chemical Physics · Physics 2022-11-23 Dipanjali Halder , V. S. Prasannaa , Rahul Maitra

Quantum embedding methods have recently developed significantly to model large molecular structures. This work proposes a novel wave function theory in density functional theory (WTF-in-DFT) embedding scheme based on pair-coupled cluster…

Chemical Physics · Physics 2024-01-10 Rahul Chakraborty , Katharina Boguslawski , Paweł Tecmer

We report an experimental realization of adaptive Bayesian quantum state tomography for two-qubit states. Our implementation is based on the adaptive experimental design strategy proposed in [F.Husz\'ar and N.M.T.Houlsby, Phys.Rev.A 85,…

Machine learning methods have been used to infer specific properties of limited families of optical quantum states, but a unified model that predicts a broad range of properties for practically relevant-especially multimode…

Quantum Physics · Physics 2025-12-23 Xiaoting Gao , Yan Zhu , Feng-Xiao Sun , Ya-Dong Wu , Qiongyi He

We develop error-tolerant quantum state discrimination(QSD) strategies that maintain reliable performance under moderate noise. Two complementary approaches are proposed: CrossQSD, which generalizes unambiguous discrimination with tunable…

Quantum Physics · Physics 2026-05-19 Chien-Kai Ma , Bo-Hung Chen , Tian-Fu Chen , Dah-Wei Chiou , Jie-Hong Roland Jiang

The task of learning a quantum circuit to prepare a given mixed state is a fundamental quantum subroutine. We present a variational quantum algorithm (VQA) to learn mixed states which is suitable for near-term hardware. Our algorithm…

Clustering algorithms are fundamental tools across many fields, with density-based methods offering particular advantages in identifying arbitrarily shaped clusters and handling noise. However, their effectiveness is often limited by the…

Machine Learning · Computer Science 2025-12-01 Meysam Shirdel Bilehsavar , Razieh Ghaedi , Samira Seyed Taheri , Xinqi Fan , Christian O'Reilly

Adaptive techniques have important potential for wide applications in enhancing precision of quantum parameter estimation. We present a recursively adaptive quantum state tomography (RAQST) protocol for finite dimensional quantum systems…

Current quantum computing hardware is restricted by the availability of only few, noisy qubits which limits the investigation of larger, more complex molecules in quantum chemistry calculations on quantum computers in the near-term. In this…

In the present work, we present a hybrid quantum-classical workflow aimed at improving the accuracy of alchemical free energy (AFE) predictions by incorporating configuration interaction (CI) simulations using the book-ending correction…

Chemical Physics · Physics 2025-06-27 Milana Bazayeva , Zhen Li , Danil Kaliakin , Fangchun Liang , Akhil Shajan , Susanta Das , Kenneth M. Merz

Quantum state preparation involves preparing a target state from an initial system, a process integral to applications such as quantum machine learning and solving systems of linear equations. Recently, there has been a growing interest in…

Quantum Physics · Physics 2024-05-08 Shuwen Kan , Miguel Palma , Zefan Du , Samuel A Stein , Chenxu Liu , Juntao Chen , Ang Li , Ying Mao

Hybrid quantum mechanical-molecular mechanical (QM/MM) simulations are widely used in enzyme simulation. Over ten convergence studies of QM/MM methods have revealed over the past several years that key energetic and structural properties…

Chemical Physics · Physics 2017-01-11 Maria Karelina , Heather J. Kulik

The structure of oxide-supported metal nanoclusters plays an essential role in their sharply enhanced catalytic activity over bulk metals. Simulations provide the atomic-scale resolution needed to understand these systems. However, the…

Materials Science · Physics 2024-05-22 Benjamin X. Shi , David J. Wales , Angelos Michaelides , Chang Woo Myung

The development of various dynamic ansatz-constructing techniques has ushered in a new era, rendering the practical exploitation of Noisy Intermediate-Scale Quantum (NISQ) hardware for molecular simulations increasingly viable. However,…

Quantum Physics · Physics 2023-10-13 Sonaldeep Halder , Anish Dey , Chinmay Shrikhande , Rahul Maitra

Accurately modeling chemical reactions at the atomistic level requires high-level electronic structure theory due to the presence of unpaired electrons and the need to properly describe bond breaking and making energetics. Commonly used…

Quantum-selected configuration interaction (QSCI) has emerged as a feasible approach for approximating electronic ground states on noisy quantum devices toward large-system demonstrations. In QSCI, Slater determinants are sampled from a…

Quantum Physics · Physics 2026-04-14 Ryota Kemmoku , Qi Gao , Shu Kanno , Kimberlee Keithley , Ikko Hamamura , Naoki Yamamoto , Kouhei Nakaji