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The human brain dynamically integrated and configured information to adapt to the environment. To capture these changes over time, dynamic second-order functional connectivity was typically used to capture transient brain patterns. However,…

Neurons and Cognition · Quantitative Biology 2025-07-01 Qiang Li , Vince D. Calhoun , Armin Iraji

Cognition is increasingly framed in terms of information processing, yet most fMRI analyses focus on activation or functional connectivity rather than quantifying how information is stored and transferred. To remedy this problem, we propose…

Neurons and Cognition · Quantitative Biology 2026-02-04 Chetan Gohil , Oliver M. Cliff , James M. Shine , Ben D. Fulcher , Joseph T. Lizier

Several data-driven approaches based on information theory have been proposed for analyzing high-order interactions involving three or more components of a network system. Most of these methods are defined only in the time domain and rely…

Applications · Statistics 2025-03-18 Yuri Antonacci , Chiara Bara' , Laura Sparacino , Gorana Mijatovic , Ludovico Minati , Luca Faes

Brain network analysis is a useful approach to studying human brain disorders because it can distinguish patients from healthy people by detecting abnormal connections. Due to the complementary information from multiple modal neuroimages,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Qiankun Zuo , Yanfei Zhu , Libin Lu , Zhi Yang , Yuhui Li , Ning Zhang

In real-world recommendation scenarios, users typically engage with platforms through multiple types of behavioral interactions. Multi-behavior recommendation algorithms aim to leverage various auxiliary user behaviors to enhance prediction…

Information Retrieval · Computer Science 2025-07-22 Hengyu Zhang , Chunxu Shen , Xiangguo Sun , Jie Tan , Yanchao Tan , Yu Rong , Hong Cheng , Lingling Yi

Alzheimer's disease progression prediction is critical for patients with early Mild Cognitive Impairment (MCI) to enable timely intervention and improve their quality of life. While existing progression prediction techniques demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Zhongying Deng , Shujun Wang , Angelica I Aviles-Rivero , Zoe Kourtzi , Carola-Bibiane Schönlieb

In neuroscience, methods from information geometry (IG) have been successfully applied in the modelling of binary vectors from spike train data, using the orthogonal decomposition of the Kullback-Leibler divergence and mutual information to…

Neurons and Cognition · Quantitative Biology 2025-10-17 Eric Albers , Paul Marriott , Masami Tatsuno

Using multimodal neuroimaging data to characterize brain network is currently an advanced technique for Alzheimer's disease(AD) Analysis. Over recent years the neuroimaging community has made tremendous progress in the study of…

Computer Vision and Pattern Recognition · Computer Science 2021-07-22 Junren Pan , Baiying Lei , Yanyan Shen , Yong Liu , Zhiguang Feng , Shuqiang Wang

Functional magnetic resonance imaging (fMRI) is a powerful tool for probing brain function, yet reliable clinical diagnosis is hampered by low signal-to-noise ratios, inter-subject variability, and the limited frequency awareness of…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Junhao Jia , Yifei Sun , Yunyou Liu , Cheng Yang , Changmiao Wang , Feiwei Qin , Yong Peng , Wenwen Min

Integration of data from multiple omics techniques is becoming increasingly important in biomedical research. Due to non-uniformity and technical limitations in omics platforms, such integrative analyses on multiple omics, which we refer to…

Machine Learning · Computer Science 2021-02-11 Changhee Lee , Mihaela van der Schaar

Psychological network approaches propose to see symptoms or questionnaire items as interconnected nodes, with links between them reflecting pairwise statistical dependencies evaluated cross-sectional, time-series, or panel data. These…

Human Object Interaction (HOI) detection is a challenging task that requires to distinguish the interaction between a human-object pair. Attention based relation parsing is a popular and effective strategy utilized in HOI. However, current…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Jingjia Huang , Baixiang Yang

Early diagnosis of mild cognitive impairment (MCI) and subjective cognitive decline (SCD) utilizing multi-modal magnetic resonance imaging (MRI) is a pivotal area of research. While various regional and connectivity features from functional…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Xiongri Shen , Zhenxi Song , Linling Li , Min Zhang , Lingyan Liang Honghai Liu , Demao Deng , Zhiguo Zhang

Contemporary neuroscience has embraced network science to study the complex and self-organized structure of the human brain; one of the main outstanding issues is that of inferring from measure data, chiefly functional Magnetic Resonance…

Optimization and Control · Mathematics 2017-03-31 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

Developing interpretable models for neurodevelopmental disorders (NDDs) diagnosis presents significant challenges in effectively encoding, decoding, and integrating multimodal neuroimaging data. While many existing machine learning…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Yueyang Li , Lei Chen , Wenhao Dong , Shengyu Gong , Zijian Kang , Boyang Wei , Weiming Zeng , Hongjie Yan , Lingbin Bian , Zhiguo Zhang , Wai Ting Siok , Nizhuan Wang

The study of irreducible higher-order interactions has become a core topic of study in complex systems. Two of the most well-developed frameworks, topological data analysis and multivariate information theory, aim to provide formal tools…

Information Theory · Computer Science 2025-04-15 Thomas F. Varley , Pedro A. M. Mediano , Alice Patania , Josh Bongard

Developing a new diagnostic models based on the underlying biological mechanisms rather than subjective symptoms for psychiatric disorders is an emerging consensus. Recently, machine learning-based classifiers using functional connectivity…

Signal Processing · Electrical Eng. & Systems 2024-10-14 Kaizhong Zheng , Shujian Yu , Baojuan Li , Robert Jenssen , Badong Chen

O-information is an information-theoretic metric that captures the overall balance between redundant and synergistic information shared by groups of three or more variables. To complement the global assessment provided by this metric, here…

Our goal in this paper is to leverage the potential of the topological signal processing (TSP) framework for analyzing brain networks. Representing brain data as signals over simplicial complexes allows us to capture higher-order…

Signal Processing · Electrical Eng. & Systems 2025-04-11 Breno C. Bispo , Stefania Sardellitti , Fernando A. N. Santos , Juliano B. Lima

Brain imaging classification is commonly approached from two perspectives: modeling the full image volume to capture global anatomical context, or constructing ROI-based graphs to encode localized and topological interactions. Although both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Wei Liang , Lifang He