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Leveraging the Segment Anything Model (SAM) for medical image segmentation remains challenging due to its limited adaptability across diverse medical domains. Although fine-tuned variants, such as MedSAM, improve performance in scenarios…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Jianghao Wu , Yicheng Wu , Yutong Xie , Wenjia Bai , You Zhang , Feilong Tang , Yulong Li , Imran Razzak , Daniel F Schmidt , Yasmeen George

Medical image segmentation is critical for clinical diagnosis, treatment planning, and monitoring, yet segmentation models often struggle with uncertainties stemming from occlusions, ambiguous boundaries, and variations in imaging devices.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Xiao Ma , Yuhui Tao , Zetian Zhang , Yuhan Zhang , Xi Wang , Sheng Zhang , Zexuan Ji , Yizhe Zhang , Qiang Chen , Guang Yang

Due to the scarcity of annotated data and the substantial computational costs of model, conventional tuning methods in medical image segmentation face critical challenges. Current approaches to adapting pretrained models, including…

Computer Vision and Pattern Recognition · Computer Science 2025-12-05 Chenlin Xu , Lei Zhang , Lituan Wang , Xinyu Pu , Pengfei Ma , Guangwu Qian , Zizhou Wang , Yan Wang

Foundation medical segmentation models, with MedSAM being the most popular, have achieved promising performance across organs and lesions. However, MedSAM still suffers from compromised performance on specific lesions with intricate…

Quantitative Methods · Quantitative Biology 2025-07-16 Kecheng Chen , Xinyu Luo , Tiexin Qin , Jie Liu , Hui Liu , Victor Ho Fun Lee , Hong Yan , Haoliang Li

Background: We evaluate SAM 2 for surgical scene understanding by examining its semantic segmentation capabilities for organs/tissues both in zero-shot scenarios and after fine-tuning. Methods: We utilized five public datasets to evaluate…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Devanish N. Kamtam , Joseph B. Shrager , Satya Deepya Malla , Xiaohan Wang , Nicole Lin , Juan J. Cardona , Serena Yeung-Levy , Clarence Hu

Deep-learning models have been successful in biomedical image segmentation. To generalize for real-world deployment, test-time augmentation (TTA) methods are often used to transform the test image into different versions that are hopefully…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Kangxian Xie , Siyu Huang , Sebastian Andres Cajas Ordonez , Hanspeter Pfister , Donglai Wei

While the Segment Anything Model (SAM) excels in semantic segmentation for general-purpose images, its performance significantly deteriorates when applied to medical images, primarily attributable to insufficient representation of medical…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yiming Zhang , Tianang Leng , Kun Han , Xiaohui Xie

The reliance on large labeled datasets presents a significant challenge in medical image segmentation. Few-shot learning offers a potential solution, but existing methods often still require substantial training data. This paper proposes a…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Haiyue Zu , Jun Ge , Heting Xiao , Jile Xie , Zhangzhe Zhou , Yifan Meng , Jiayi Ni , Junjie Niu , Linlin Zhang , Li Ni , Huilin Yang

We introduce Generalized Test-Time Augmentation (GTTA), a highly effective method for improving the performance of a trained model, which unlike other existing Test-Time Augmentation approaches from the literature is general enough to be…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Andrei Jelea , Ahmed Nabil Belbachir , Marius Leordeanu

This paper presents an effective and general data augmentation framework for medical image segmentation. We adopt a computationally efficient and data-efficient gradient-based meta-learning scheme to explicitly align the distribution of…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Zeju Li , Konstantinos Kamnitsas , Qi Dou , Chen Qin , Ben Glocker

Medical image segmentation is vital for clinical diagnosis and quantitative analysis, yet remains challenging due to the heterogeneity of imaging modalities and the high cost of pixel-level annotations. Although general interactive…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yujie Lu , Jingwen Li , Sibo Ju , Yanzhou Su , he yao , Yisong Liu , Min Zhu , Junlong Cheng

Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Anwai Archit , Luca Freckmann , Constantin Pape

Deep learning semantic segmentation algorithms can localise abnormalities or opacities from chest radiographs. However, the task of collecting and annotating training data is expensive and requires expertise which remains a bottleneck for…

Image and Video Processing · Electrical Eng. & Systems 2021-02-26 Jitesh Seth , Rohit Lokwani , Viraj Kulkarni , Aniruddha Pant , Amit Kharat

Universal medical image segmentation models have emerged as a promising paradigm due to their strong generalizability across diverse tasks, showing great potential for a wide range of clinical applications. This potential has been partly…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Yanwu Yang , Guinan Su , Jiesi Hu , Francesco Sammarco , Jonas Geiping , Thomas Wolfers

The recently released Segment Anything Model (SAM) has shown powerful zero-shot segmentation capabilities through a semi-automatic annotation setup in which the user can provide a prompt in the form of clicks or bounding boxes. There is…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Benjamin Towle , Xin Chen , Ke Zhou

Test-time augmentation (TTA)--aggregating predictions over multiple augmented copies of a test input--is widely assumed to improve classification accuracy, particularly in medical imaging where it is routinely deployed in production systems…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Daniel Nobrega Medeiros

Segmentation quality assessment (SQA) plays a critical role in the deployment of a medical image based AI system. Users need to be informed/alerted whenever an AI system generates unreliable/incorrect predictions. With the introduction of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Yizhe Zhang , Shuo Wang , Tao Zhou , Qi Dou , Danny Z. Chen

Medical image segmentation plays a pivotal role in clinical diagnostics and treatment planning, yet existing models often face challenges in generalization and in handling both 2D and 3D data uniformly. In this paper, we introduce Medical…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Jiayuan Zhu , Abdullah Hamdi , Yunli Qi , Yueming Jin , Junde Wu

Foundation models like the Segment Anything Model (SAM) excel in zero-shot segmentation for natural images but struggle with medical image segmentation due to differences in texture, contrast, and noise. Annotating medical images is costly…

Image and Video Processing · Electrical Eng. & Systems 2025-04-14 Sourya Sengupta , Satrajit Chakrabarty , Keerthi Sravan Ravi , Gopal Avinash , Ravi Soni

Test-time adaptation (TTA) refers to adapting a trained model to a new domain during testing. Existing TTA techniques rely on having multiple test images from the same domain, yet this may be impractical in real-world applications such as…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Haoyu Dong , Nicholas Konz , Hanxue Gu , Maciej A. Mazurowski
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