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Training medical personnel using standardized patients (SPs) remains a complex challenge, requiring extensive domain expertise and role-specific practice. Previous research on Large Language Model (LLM)-based SPs mostly focuses on improving…

Computation and Language · Computer Science 2025-06-10 Zhuoyun Du , Lujie Zheng , Renjun Hu , Yuyang Xu , Xiawei Li , Ying Sun , Wei Chen , Jian Wu , Haolei Cai , Haohao Ying

Scientific idea generation is a cornerstone of autonomous knowledge discovery, yet the iterative evolution required to transform initial concepts into high-quality research proposals remains a formidable challenge for Large Language Models…

Artificial Intelligence · Computer Science 2026-03-24 Andreas Sauter , Yuyue Zhao , Jacopo Urbani , Wenxiang Hu , Zaiqiao Meng , Lun Zhou , Xiaohui Yan , Yougang Lyu

Protein scientific discovery is bottlenecked by the manual orchestration of information and algorithms, while general agents are insufficient in complex domain projects. VenusFactory2 provides an autonomous framework that shifts from static…

Artificial Intelligence · Computer Science 2026-03-31 Yang Tan , Lingrong Zhang , Mingchen Li , Yuanxi Yu , Bozitao Zhong , Bingxin Zhou , Nanqing Dong , Liang Hong

Artificial intelligence offers powerful new tools for scientific discovery, but the interaction paradigms required to effectively harness these systems remain underexplored. In this paper, we present findings from a formative user study…

Artificial Intelligence · Computer Science 2026-05-08 Alex Bäuerle , Adam Connors , Alexander Novikov , Adam Zsolt Wagner , Ngân Vũ , Fernanda Viegas , Martin Wattenberg , Lucas Dixon

Large language models (LLMs) and vision-language models (VLMs) have the potential to transform biological research by enabling autonomous experimentation. Yet, their application remains constrained by rigid protocol design, limited…

Robotics · Computer Science 2025-07-03 Yibo Qiu , Zan Huang , Zhiyu Wang , Handi Liu , Yiling Qiao , Yifeng Hu , Shu'ang Sun , Hangke Peng , Ronald X Xu , Mingzhai Sun

Developing Large Language Model (LLM) agents that exhibit human-like behavior, encompassing not only individual heterogeneity rooted in unique user profiles but also adaptive response to socially connected neighbors, is a significant…

Social and Information Networks · Computer Science 2025-09-17 Fanqi Kong , Xiaoyuan Zhang , Xinyu Chen , Yaodong Yang , Song-Chun Zhu , Xue Feng

With the growing adoption of large language model agents in persistent real-world roles, they naturally encounter continuous streams of tasks. A key limitation, however, is their failure to learn from the accumulated interaction history,…

The advances made by Large Language Models (LLMs) have led to the pursuit of LLM agents that can solve intricate, multi-step reasoning tasks. As with any research pursuit, benchmarking and evaluation are key corner stones to efficient and…

Artificial Intelligence · Computer Science 2024-04-10 Luca Gioacchini , Giuseppe Siracusano , Davide Sanvito , Kiril Gashteovski , David Friede , Roberto Bifulco , Carolin Lawrence

Agentic Artificial Intelligence (AI) represents a paradigm shift from reactive systems to proactive, autonomous decision making frameworks. Existing AI-based educational systems remain fragmented and lack multi-level integration across…

Multiagent Systems · Computer Science 2026-04-21 Arya Mary K J , Deepthy K Bhaskar , Sinu T S , Binu V P

Experience-driven self-evolving agents aim to overcome the static nature of large language models by distilling reusable experience from past interactions, thus enabling adaptation to novel tasks at deployment time. This process places…

Artificial Intelligence · Computer Science 2026-05-12 Zhiyuan Fan , Wenwei Jin , Feng Zhang , Bin Li , Yihong Dong , Yao Hu , Jiawei Li

Fully automated self-driving laboratories are promising to enable high-throughput and large-scale scientific discovery by reducing repetitive labour. However, effective automation requires deep integration of laboratory knowledge, which is…

Artificial Intelligence · Computer Science 2025-09-30 Shuxiang Cao , Zijian Zhang , Mohammed Alghadeer , Simone D Fasciati , Michele Piscitelli , Mustafa Bakr , Peter Leek , Alán Aspuru-Guzik

Advances in LLMs have produced agents with knowledge and operational capabilities comparable to human scientists, suggesting potential to assist, accelerate, and automate research. However, existing studies mainly evaluate such systems on…

Building LLM-based agents has become increasingly important. Recent works on LLM-based agent self-evolution primarily record successful experiences as textual prompts or reflections, which cannot reliably guarantee efficient task…

Artificial Intelligence · Computer Science 2026-03-19 Zhang Zhang , Shuqi Lu , Hongjin Qian , Di He , Zheng Liu

Automatic research with Large Language Models (LLMs) is rapidly gaining importance, driving the development of increasingly complex workflows involving multi-agent systems, planning, tool usage, code execution, and human-agent interaction…

Computation and Language · Computer Science 2025-10-09 Haofei Yu , Keyang Xuan , Fenghai Li , Kunlun Zhu , Zijie Lei , Jiaxun Zhang , Ziheng Qi , Kyle Richardson , Jiaxuan You

Given the remarkable performance of Large Language Models (LLMs), an important question arises: Can LLMs conduct human-like scientific research and discover new knowledge, and act as an AI scientist? Scientific discovery is an iterative…

Machine Learning · Computer Science 2025-02-24 Tingting Chen , Srinivas Anumasa , Beibei Lin , Vedant Shah , Anirudh Goyal , Dianbo Liu

Artificial intelligence has shown promise in medical imaging, yet most existing systems lack flexibility, interpretability, and adaptability - challenges especially pronounced in ophthalmology, where diverse imaging modalities are…

Large language model (LLM) applications such as agents and domain-specific reasoning increasingly rely on context adaptation: modifying inputs with instructions, strategies, or evidence, rather than weight updates. Prior approaches improve…

While foundation models (FMs), such as diffusion models and large vision-language models (LVLMs), have been widely applied in educational contexts, their ability to generate pedagogically effective visual explanations remains limited. Most…

Artificial Intelligence · Computer Science 2025-05-29 Haonian Ji , Shi Qiu , Siyang Xin , Siwei Han , Zhaorun Chen , Dake Zhang , Hongyi Wang , Huaxiu Yao

Motivation: Agent-based modeling is an indispensable tool for studying complex biological systems. However, existing simulators do not always take full advantage of modern hardware and often have a field-specific software design. Results:…

A growing body of work pursues AI scientists capable of end-to-end autonomous scientific discovery. This position paper argues that although they already function as co-scientists, agentic AI scientists are not built for autonomous…

Artificial Intelligence · Computer Science 2026-05-12 Harshit Bisht , Vinay Kumar , Kevin Maik Jablonka , Mausam , N. M. Anoop Krishnan