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Multimodal imaging has shown great potential in cancer research by concurrently providing anatomical, functional, and molecular information in live, intact animals. During preclinical imaging of small animals like mice, anesthesia is…

Medical Physics · Physics 2024-10-11 Wenxuan Xue , Yuxuan Liang , Mengzhou Li , Shan Gao , Xavier R. Intes , Ge Wang

Monitoring maternal and fetal health during pregnancy is crucial for preventing adverse outcomes. While tests such as ultrasound scans offer high accuracy, they can be costly and inconvenient. Telehealth and more accessible body shape…

We present the results of three separate searches for HI 21-cm absorption in a total of twelve damped Lyman-alpha absorption systems (DLAs) and sub-DLAs over the redshift range z = 0.86-3.37. We find no absorption in the five systems for…

Cosmology and Nongalactic Astrophysics · Physics 2015-05-14 S. J. Curran , P. Tzanavaris , J. K. Darling , M. T. Whiting , J. K. Webb C. Bignell , R. Athreya , M. T. Murphy

We present a neutral hydrogen-selected absorption-line survey of gas with HI column densities 15<log N(HI)<19 at z<1 using the Cosmic Origins Spectrograph on the Hubble Space Telescope. Our main aim is to determine the metallicity…

Mammography, the current standard for breast cancer screening, has reduced sensitivity in women with dense breast tissue, contributing to missed or delayed diagnoses. Thermalytix, an AI-based thermal imaging modality, captures functional…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Siva Teja Kakileti , Bharath Govindaraju , Sudhakar Sampangi , Geetha Manjunath

Three-dimensional reconstruction of cortical surfaces from MRI for morphometric analysis is fundamental for understanding brain structure. While high-field MRI (HF-MRI) is standard in research and clinical settings, its limited availability…

We are concerned with the estimation of the exterior surface and interior summaries of tube-shaped anatomical structures. This interest is motivated by two distinct scientific goals, one dealing with the distribution of HIV microbicide in…

Applications · Statistics 2011-04-18 Jeff Goldsmith , Brian Caffo , Ciprian Crainiceanu , Daniel Reich , Yong Du , Craig Hendrix

This work presents a comparative evaluation of two fundamentally different feature extraction paradigms--Histogram of Oriented Gradients (HOG) and Topological Data Analysis (TDA)--for medical image classification, with a focus on retinal…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Faisal Ahmed

Quantifying muscle tissue properties is crucial for understanding pathophysiological changes occurring in skeletal muscle (SM). In particular, T2 relaxation and diffusion MRI (dMRI) are promising techniques. However, typical methods measure…

Contraction assay based on surface measurement have been widely used to evaluate cell contractility in 3D models. This method is straightforward and requires no specific equipment, but it does not provide quantitative data about contraction…

By combining the data from surveys for HI 21-cm absorption at various impact parameters in near-by galaxies, we report an anti-correlation between the 21-cm absorption strength (velocity integrated optical depth) and the impact parameter.…

Astrophysics of Galaxies · Physics 2016-04-27 S. J. Curran , S. N. Reeves , J. R. Allison , E. M. Sadler

4D scans of dynamic deformable human body parts help researchers have a better understanding of spatiotemporal features. However, reconstructing 4D scans based on multiple asynchronous cameras encounters two main challenges: 1) finding the…

Image and Video Processing · Electrical Eng. & Systems 2023-07-25 Farzam Tajdari , Toon Huysmans , Xinhe Yao , Jun Xu , Yu Song

High Content Screening (HCS) microscopy datasets have transformed the ability to profile cellular responses to genetic and chemical perturbations, enabling cell-based inference of drug-target interactions (DTI). However, the adoption of…

Purpose: Body composition measurements from routine abdominal CT can yield personalized risk assessments for asymptomatic and diseased patients. In particular, attenuation and volume measures of muscle and fat are associated with important…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Benjamin Hou , Tejas Sudharshan Mathai , Jianfei Liu , Christopher Parnell , Ronald M. Summers

Large vision models based in deep learning architectures have been consistently advancing the state-of-the-art in biometric recognition. However, three weaknesses are commonly reported for such kind of approaches: 1) their extreme demands…

Computer Vision and Pattern Recognition · Computer Science 2024-06-27 Henrique Jesus , Hugo Proença

We present a method to discover differences between populations with respect to the spatial coherence of their oriented white matter microstructure in arbitrarily shaped white matter regions. This method is applied to diffusion MRI scans of…

Plastic scintillation detectors are increasingly used to measure dose distributions in the context of radiotherapy treatments. Their water-equivalence, real-time response and high spatial resolution distinguish them from traditional…

Medical Physics · Physics 2021-09-22 Emily Cloutier , Louis Archambault , Luc Beaulieu

Objective: To analyze the frequency and co-occurrence of dermoscopic patterns in BCC lesions and their relationship with histopathologic subtypes, using statistical analysis and Information Theory tools such as entropy, conditional entropy,…

Quantitative Methods · Quantitative Biology 2025-04-08 Iván Matas , Begoña Acha , Francisca Silva-Clavería , Amalia Serrano , Tomás Toledo-Pastrana , Carmen Serrano

We describe algorithms that detect 21cm line HI self-absorption (HISA) in large data sets and extract it for analysis. Our search method identifies HISA as spatially and spectrally confined dark HI features that appear as negative residuals…

MR-derived radiomic features have demonstrated substantial predictive utility in modeling different prognostic factors of glioblastomas and other brain cancers. However, the biological relationship underpinning these predictive models has…

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