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Causality lies at the heart of scientific inquiry, serving as the fundamental basis for understanding interactions among variables in physical systems. Despite its central role, current methods for causal inference face significant…

Data Analysis, Statistics and Probability · Physics 2025-05-19 Álvaro Martínez-Sánchez , Gonzalo Arranz , Adrián Lozano-Durán

Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

Artificial Intelligence · Computer Science 2026-01-30 Abhijith Shaji , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Greg Ver Steeg , Paul M. Thompson , Jose-Luis Ambite

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease characterized by progressive cognitive decline as its main symptom. In the research field of deep learning-assisted diagnosis of AD, traditional convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Yang Ming , Jiang Shi Zhong , Zhou Su Juan

Reliability in Neural Networks (NNs) is crucial in safety-critical applications like healthcare, and uncertainty estimation is a widely researched method to highlight the confidence of NNs in deployment. In this work, we propose an…

Machine Learning · Computer Science 2020-11-20 Utkarsh Sarawgi , Wazeer Zulfikar , Rishab Khincha , Pattie Maes

Improving the accessibility of psychotherapy with the aid of Large Language Models (LLMs) is garnering a significant attention in recent years. Recognizing cognitive distortions from the interviewee's utterances can be an essential part of…

Computation and Language · Computer Science 2024-03-22 Sehee Lim , Yejin Kim , Chi-Hyun Choi , Jy-yong Sohn , Byung-Hoon Kim

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

The integration of multi-modal Magnetic Resonance Imaging (MRI) and clinical data holds great promise for enhancing the diagnosis of neurological disorders (NDs) in real-world clinical settings. Deep Learning (DL) has recently emerged as a…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Wajih Hassan Raza , Aamir Bader Shah , Yu Wen , Yidan Shen , Juan Diego Martinez Lemus , Mya Caryn Schiess , Timothy Michael Ellmore , Renjie Hu , Xin Fu

Multimodal imaging has transformed neuroscience research. While it presents unprecedented opportunities, it also imposes serious challenges. Particularly, it is difficult to combine the merits of the interpretability attributed to a simple…

Methodology · Statistics 2021-11-25 Xiaowu Dai , Lexin Li

Radiation hazards associated with standard-dose positron emission tomography (SPET) images remain a concern, whereas the quality of low-dose PET (LPET) images fails to meet clinical requirements. Therefore, there is great interest in…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Jiaqi Cui , Xinyi Zeng , Pinxian Zeng , Bo Liu , Xi Wu , Jiliu Zhou , Yan Wang

Diabetic retinopathy (DR) is a leading cause of preventable blindness worldwide, demanding accurate automated diagnostic systems. While general-domain vision-language models like Contrastive Language-Image Pre-Training (CLIP) perform well…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Argha Kamal Samanta , Harshika Goyal , Vasudha Joshi , Tushar Mungle , Pabitra Mitra

Learning multimodal representations from medical images and other data sources can provide richer information for decision-making. While various multimodal models have been developed for this, they overlook learning features that are both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Boyu Chen , Weiye Bao , Junjie Liu , Michael Shen , Bo Peng , Paul Taylor , Zhu Li , Mengyue Yang

Image degradation from blur, noise, compression, and poor illumination severely undermines multimodal understanding in real-world settings. Unified multimodal models that combine understanding and generation within a single architecture are…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Xiangzhao Hao , Zefeng Zhang , Zhenyu Zhang , Linhao Yu , Yao Chen , Yiqian Zhang , Haiyun Guo , Shuohuan Wang , Yu Sun

We introduce a new dataset, MELINDA, for Multimodal biomEdicaL experImeNt methoD clAssification. The dataset is collected in a fully automated distant supervision manner, where the labels are obtained from an existing curated database, and…

Computation and Language · Computer Science 2020-12-18 Te-Lin Wu , Shikhar Singh , Sayan Paul , Gully Burns , Nanyun Peng

Computer-aided diagnosis (CAD) is becoming a prominent approach to assist clinicians spanning across multiple fields. These automated systems take advantage of various computer vision (CV) procedures, as well as artificial intelligence (AI)…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Danilo Avola , Luigi Cinque , Alessio Fagioli , Sebastiano Filetti , Giorgio Grani , Emanuele Rodolà

Major Adverse Cardiovascular Events (MACE) remain the leading cause of mortality globally, as reported in the Global Disease Burden Study 2021. Opportunistic screening leverages data collected from routine health check-ups and multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Jialu Pi , Juan Maria Farina , Rimita Lahiri , Jiwoong Jeong , Archana Gurudu , Hyung-Bok Park , Chieh-Ju Chao , Chadi Ayoub , Reza Arsanjani , Imon Banerjee

Causal representation learning (CRL) seeks to uncover meaningful latent variables and their corresponding causal structure from high-dimensional observational data. Although its significance, CRL identifiability remains a crucial property,…

Machine Learning · Computer Science 2026-05-20 Manal Benhamza , Marianne Clausel , Myriam Tami

Substantial advances in multi-modal Artificial Intelligence (AI) facilitate the combination of diverse medical modalities to achieve holistic health assessments. We present COMPRER , a novel multi-modal, multi-objective pretraining…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Guy Lutsker , Hagai Rossman , Nastya Godiva , Eran Segal

Multimodal neuroimaging provides complementary insights for Alzheimer's disease diagnosis, yet clinical datasets frequently suffer from missing modalities. We propose ACADiff, a framework that synthesizes missing brain imaging modalities…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Rong Zhou , Houliang Zhou , Yao Su , Brian Y. Chen , Yu Zhang , Lifang He , Alzheimer's Disease Neuroimaging Initiative

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

In recent years, cross-modal reasoning (CMR), the process of understanding and reasoning across different modalities, has emerged as a pivotal area with applications spanning from multimedia analysis to healthcare diagnostics. As the…

Artificial Intelligence · Computer Science 2023-09-15 Dizhan Xue , Shengsheng Qian , Zuyi Zhou , Changsheng Xu