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Prompt engineering has emerged as a powerful technique for guiding large language models (LLMs) toward desired responses, significantly enhancing their performance across diverse tasks. Beyond their role as static predictors, LLMs…

Machine Learning · Computer Science 2025-03-27 Ryumei Nakada , Wenlong Ji , Tianxi Cai , James Zou , Linjun Zhang

This paper studies close-loop task planning, which refers to the process of generating a sequence of skills (a plan) to accomplish a specific goal while adapting the plan based on real-time observations. Recently, prompting Large Language…

Computation and Language · Computer Science 2024-07-25 Mengkang Hu , Yao Mu , Xinmiao Yu , Mingyu Ding , Shiguang Wu , Wenqi Shao , Qiguang Chen , Bin Wang , Yu Qiao , Ping Luo

Language Models (LMs) excel in understanding textual descriptions of proteins, as evident in biomedical question-answering tasks. However, their capability falters with raw protein data, such as amino acid sequences, due to a deficit in…

Quantitative Methods · Quantitative Biology 2024-05-22 Zhiyuan Liu , An Zhang , Hao Fei , Enzhi Zhang , Xiang Wang , Kenji Kawaguchi , Tat-Seng Chua

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

Computation and Language · Computer Science 2025-03-07 Jiyue Jiang , Zikang Wang , Yuheng Shan , Heyan Chai , Jiayi Li , Zixian Ma , Xinrui Zhang , Yu Li

Large language models (LLMs) have achieved remarkable success in a wide range of natural language processing tasks and can be adapted through prompting. However, they remain suboptimal in multi-turn interactions, often relying on incorrect…

Prompt engineering is critical for the development of LLM-based applications. However, it is usually done manually in a "trial and error" fashion that can be time consuming, ineffective, and sub-optimal. Even for the prompts which seemingly…

Artificial Intelligence · Computer Science 2024-06-11 Weize Kong , Spurthi Amba Hombaiah , Mingyang Zhang , Qiaozhu Mei , Michael Bendersky

We present QueryGym, a lightweight, extensible Python toolkit that supports large language model (LLM)-based query reformulation. This is an important tool development since recent work on llm-based query reformulation has shown notable…

Information Retrieval · Computer Science 2025-11-21 Amin Bigdeli , Radin Hamidi Rad , Mert Incesu , Negar Arabzadeh , Charles L. A. Clarke , Ebrahim Bagheri

Prompt engineering is a new paradigm for enhancing the performance of trained neural network models. For optimizing text-style prompts, existing methods usually individually operate small portions of a text step by step, which either breaks…

Computation and Language · Computer Science 2023-10-03 Yujian Betterest Li , Kai Wu

Agentic workflows, where multiple AI agents collaborate to accomplish complex tasks like reasoning or planning, play a substantial role in many cutting-edge commercial applications, and continue to fascinate researchers across fields for…

Computation and Language · Computer Science 2025-11-10 Deepak Pandita , Tharindu Cyril Weerasooriya , Ankit Parag Shah , Isabelle Diana May-Xin Ng , Christopher M. Homan , Wei Wei

As knowledge and semantics on the web grow increasingly complex, enhancing Large Language Models (LLMs)' comprehension and reasoning capabilities has become particularly important. Chain-of-Thought (CoT) prompting has been shown to enhance…

Artificial Intelligence · Computer Science 2026-01-21 Ke Chen , Jiandian Zeng , Zihao Peng , Guo Li , Guangxue Zhang , Tian Wang

Despite their linguistic competence, Large Language Models (LLMs) often struggle to reason reliably and flexibly. To identify these shortcomings, we introduce the Non-Linear Reasoning (NLR) dataset, a collection of 55 unique, hand-designed…

Computation and Language · Computer Science 2025-12-02 Nasim Borazjanizadeh , Steven T. Piantadosi

Self-Correction aims to enable large language models (LLMs) to self-verify and self-refine their initial responses without external feedback. However, LLMs often fail to effectively self-verify and generate correct feedback, further…

Computation and Language · Computer Science 2025-05-28 Xiaoshuai Song , Yanan Wu , Weixun Wang , Jiaheng Liu , Wenbo Su , Bo Zheng

Pre-trained language models (PrLM) have to carefully manage input units when training on a very large text with a vocabulary consisting of millions of words. Previous works have shown that incorporating span-level information over…

Computation and Language · Computer Science 2021-09-16 Rongzhou Bao , Zhuosheng Zhang , Hai Zhao

Designing de novo proteins beyond those found in nature holds significant promise for advancements in both scientific and engineering applications. Current methodologies for protein design often rely on AI-based models, such as surrogate…

Soft Condensed Matter · Physics 2024-02-08 A. Ghafarollahi , M. J. Buehler

Prefix circuits are fundamental components in digital adders, widely used in digital systems due to their efficiency in calculating carry signals. Synthesizing prefix circuits with minimized area and delay is crucial for enhancing the…

Hardware Architecture · Computer Science 2024-12-04 Weihua Xiao , Venkata Sai Charan Putrevu , Raghu Vamshi Hemadri , Siddharth Garg , Ramesh Karri

Machine learning practitioners often face significant challenges in formally integrating their prior knowledge and beliefs into predictive models, limiting the potential for nuanced and context-aware analyses. Moreover, the expertise needed…

Machine Learning · Statistics 2024-12-23 James Requeima , John Bronskill , Dami Choi , Richard E. Turner , David Duvenaud

While machine learning has transformed polymer design by enabling rapid property prediction and candidate generation, translating these designs into experimentally realizable materials remains a critical challenge. Traditionally, the…

Soft Condensed Matter · Physics 2025-12-08 Sakshi Agarwal , Wei Xiong , Rampi Ramprasad

Effective prompt engineering is critical to realizing the promised productivity gains of large language models (LLMs) in knowledge-intensive tasks. Yet, many users struggle to craft prompts that yield high-quality outputs, limiting the…

Human-Computer Interaction · Computer Science 2025-10-02 Niklas Gutheil , Valentin Mayer , Leopold Müller , Jörg Rommelt , Niklas Kühl

Large language models (LLMs) have shown strong performance in many reasoning benchmarks. However, recent studies have pointed to memorization, rather than generalization, as one of the leading causes for such performance. LLMs, in fact, are…

Computation and Language · Computer Science 2025-09-19 Xingwei Tan , Marco Valentino , Mahmud Akhter , Maria Liakata , Nikolaos Aletras

Semiconductor supply chains face unprecedented resilience challenges amidst global geopolitical turbulence. Conventional Large Language Model (LLM) planners, when confronting such non-stationary "Policy Black Swan" events, frequently suffer…

Artificial Intelligence · Computer Science 2026-04-14 Jia Luo