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Clinical trials are pivotal for developing new medical treatments but typically carry risks such as patient mortality and enrollment failure that waste immense efforts spanning over a decade. Applying artificial intelligence (AI) to predict…

Deep learning has the potential to automate many clinically useful tasks in medical imaging. However translation of deep learning into clinical practice has been hindered by issues such as lack of the transparency and interpretability in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-04 Charles Lu , Andreanne Lemay , Ken Chang , Katharina Hoebel , Jayashree Kalpathy-Cramer

While interest in the application of machine learning to improve healthcare has grown tremendously in recent years, a number of barriers prevent deployment in medical practice. A notable concern is the potential to exacerbate entrenched…

Machine Learning · Computer Science 2022-05-19 Isabel Chien , Nina Deliu , Richard E. Turner , Adrian Weller , Sofia S. Villar , Niki Kilbertus

Medical Visual Language Models have shown great potential in various healthcare applications, including medical image captioning and diagnostic assistance. However, most existing models rely on text-based instructions, limiting their…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Tan-Hanh Pham , Chris Ngo , Trong-Duong Bui , Minh Luu Quang , Tan-Huong Pham , Truong-Son Hy

Artificial intelligence (AI) that can effectively learn ultrasound representations by integrating multi-source data holds significant promise for advancing clinical care. However, the scarcity of large labeled datasets in real-world…

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

Deep neural networks often rely on spurious correlations in training data, leading to biased or unfair predictions in safety-critical domains such as medicine and autonomous driving. While conventional bias mitigation typically requires…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Sai Siddhartha Chary Aylapuram , Veeraraju Elluru , Shivang Agarwal

Multimodal Large Language Models (MLLMs) have demonstrated remarkable effectiveness in various general-domain scenarios, such as visual question answering and image captioning. Recently, researchers have increasingly focused on empowering…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yan Shu , Chi Liu , Robin Chen , Derek Li , Bryan Dai

Objective: This review explores the trustworthiness of multimodal artificial intelligence (AI) systems, specifically focusing on vision-language tasks. It addresses critical challenges related to fairness, transparency, and ethical…

Cryptography and Security · Computer Science 2025-05-28 Mohammad Saleh , Azadeh Tabatabaei

Artificial intelligence (AI) is increasingly being used for medical imaging tasks. However, there can be biases in AI models, particularly when they are trained using imbalanced training datasets. One such example has been the strong…

Image and Video Processing · Electrical Eng. & Systems 2026-02-04 Tiarna Lee , Esther Puyol-Antón , Bram Ruijsink , Pier-Giorgio Masci , Louise Keehn , Phil Chowienczyk , Emily Haseler , Miaojing Shi , Andrew P. King

The presence of decision-making algorithms in society is rapidly increasing nowadays, while concerns about their transparency and the possibility of these algorithms becoming new sources of discrimination are arising. There is a certain…

Trust and interpretability are crucial for the use of Artificial Intelligence (AI) in scientific research, but current models often operate as black boxes offering limited transparency and justifications for their outputs. We introduce…

Algorithmic bias in medical imaging can perpetuate health disparities, yet its causes remain poorly understood in segmentation tasks. While fairness has been extensively studied in classification, segmentation remains underexplored despite…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Aditya Parikh , Sneha Das , Aasa Feragen

Medical image segmentation is a fundamental yet challenging task due to the arduous process of acquiring large volumes of high-quality labeled data from experts. Contrastive learning offers a promising but still problematic solution to this…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Shuang Zeng , Lei Zhu , Xinliang Zhang , Micky C Nnamdi , Wenqi Shi , J Ben Tamo , Qian Chen , Hangzhou He , Lujia Jin , Zifeng Tian , Qiushi Ren , Zhaoheng Xie , Yanye Lu

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

Vision-Language Models (VLMs) inherit significant social biases from their training data, notably in gender representation. Current fairness interventions often adopt a difference-unaware perspective that enforces uniform treatment across…

Artificial Intelligence · Computer Science 2025-12-02 Yujie Lin , Jiayao Ma , Qingguo Hu , Derek F. Wong , Jinsong Su

Medical image segmentation is a critical component of clinical workflows, enabling accurate diagnosis, treatment planning, and disease monitoring. However, despite the superior performance of transformer-based models over convolutional…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Thuraya Alzubaidi , Sana Ammar , Maryam Alsharqi , Islem Rekik , Muzammil Behzad

The visual world offers a critical axis for advancing foundation models beyond language. Despite growing interest in this direction, the design space for native multimodal models remains opaque. We provide empirical clarity through…

Clinical machine learning models are increasingly trained using large scale, multimodal foundation paradigms, yet deployment environments often differ systematically from the data generating settings used during training. Such shifts arise…

Machine Learning · Computer Science 2026-03-10 Yuanyun Zhang , Shi Li

Most current audio-visual emotion recognition models lack the flexibility needed for deployment in practical applications. We envision a multimodal system that works even when only one modality is available and can be implemented…

Machine Learning · Computer Science 2026-01-13 Lucas Goncalves , Seong-Gyun Leem , Wei-Cheng Lin , Berrak Sisman , Carlos Busso
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