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Accurate imputation of missing laboratory values in electronic health records (EHRs) is critical to enable robust clinical predictions and reduce biases in AI systems in healthcare. Existing methods, such as XGBoost, softimpute, GAIN,…

Machine Learning · Computer Science 2025-06-27 David Restrepo , Chenwei Wu , Yueran Jia , Jaden K. Sun , Jack Gallifant , Catherine G. Bielick , Yugang Jia , Leo A. Celi

For medical imaging AI models to be clinically impactful, they must generalize. However, this goal is hindered by (i) diverse types of distribution shifts, such as temporal, demographic, and label shifts, and (ii) limited diversity in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Kumail Alhamoud , Yasir Ghunaim , Motasem Alfarra , Thomas Hartvigsen , Philip Torr , Bernard Ghanem , Adel Bibi , Marzyeh Ghassemi

As artificial intelligence systems move toward clinical deployment, ensuring reliable prediction behavior is fundamental for safety-critical decision-making tasks. One proposed safeguard is selective prediction, where models can defer…

Machine Learning · Computer Science 2026-05-25 L. Julián Lechuga López , Farah E. Shamout , Tim G. J. Rudner

Current clinical practice to monitor patients' health follows either regular or heuristic-based lab test (e.g. blood test) scheduling. Such practice not only gives rise to redundant measurements accruing cost, but may even lead to…

Machine Learning · Computer Science 2018-12-04 Chun-Hao Chang , Mingjie Mai , Anna Goldenberg

While frontier large language models demonstrate strong reasoning and mathematical capabilities, the practical process of training domain-specialized scientific language models from raw sources remains under-documented. In this work, we…

Artificial Intelligence · Computer Science 2026-02-20 Anuj Gupta

This commentary regards a recent simulation study conducted by Aouni, Gaudel-Dedieu and Sebastien, evaluating the performance of different versions of matching-adjusted indirect comparison (MAIC) in an anchored scenario with a common…

Methodology · Statistics 2022-03-29 Antonio Remiro-Azócar , Anna Heath , Gianluca Baio

Accurate patient mortality prediction enables effective risk stratification, leading to personalized treatment plans and improved patient outcomes. However, predicting mortality in healthcare remains a significant challenge, with existing…

Machine Learning · Computer Science 2025-03-28 HyeYoung Lee , Pavel Tsoi

While the ICD code assignment problem has been widely studied, most works have focused on post-discharge document classification. Models for early forecasting of this information could be used for identifying health risks, suggesting…

Machine Learning · Computer Science 2025-08-18 Cindy Shih-Ting Huang , Clarence Boon Liang Ng , Marek Rei

With the rise of medical foundation models and the growing availability of imaging data, scalable pretraining techniques offer a promising way to identify imaging biomarkers predictive of future disease risk. While current self-supervised…

Intensive care clinicians need reliable clinical practice tools to preempt unexpected critical events that might harm their patients in intensive care units (ICU), to pre-plan timely interventions, and to keep the patient's family well…

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

Deep learning models (aka Deep Neural Networks) have revolutionized many fields including computer vision, natural language processing, speech recognition, and is being increasingly used in clinical healthcare applications. However, few…

Machine Learning · Computer Science 2017-10-25 Sanjay Purushotham , Chuizheng Meng , Zhengping Che , Yan Liu

The rapid finding of effective therapeutics requires the efficient use of available resources in clinical trials. The use of covariate adjustment can yield statistical estimates with improved precision, resulting in a reduction in the…

Methodology · Statistics 2021-09-10 Nicholas Williams , Michael Rosenblum , Iván Díaz

Radiologists highly desire fully automated AI for radiology report generation (R2G), yet existing approaches fall short in clinical utility. Reinforcement learning (RL) holds potential to address these shortcomings, but its adoption in this…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Zilin Lu , Ruifeng Yuan , Weiwei Cao , Wanxing Chang , Zhongyu Wei , Sinuo Wang , Yong Xia , Ling Zhang , Jianpeng Zhang

Background: Stroke is second-leading cause of disability and death among adults. Approximately 17 million people suffer from a stroke annually, with about 85% being ischemic strokes. Predicting mortality of ischemic stroke patients in…

Machine Learning · Computer Science 2024-09-04 Armin Abdollahi , Negin Ashrafi , Maryam Pishgar

Clinical notes are a rich source of information about patient state. However, using them to predict clinical events with machine learning models is challenging. They are very high dimensional, sparse and have complex structure. Furthermore,…

Machine Learning · Statistics 2018-08-20 Sebastien Dubois , Nathanael Romano , David C. Kale , Nigam Shah , Kenneth Jung

Clinical event sequences consist of hundreds of clinical events that represent records of patient care in time. Developing accurate predictive models of such sequences is of a great importance for supporting a variety of models for…

Machine Learning · Computer Science 2023-08-23 Jeong Min Lee , Milos Hauskrecht

The association between preoperative cognitive status and surgical outcomes is a critical, yet scarcely explored area of research. Linking intraoperative data with postoperative outcomes is a promising and low-cost way of evaluating…

Generative recommendation models can model user behavior as sequences of events and provide a shared backbone for multiple recommendation tasks. In production, however, pre-training gains do not automatically translate into downstream…

Information Retrieval · Computer Science 2026-05-25 Qiuling Xu , Ko-Jen Hsiao , Moumita Bhattacharya

Prediction of medical codes from clinical notes is both a practical and essential need for every healthcare delivery organization within current medical systems. Automating annotation will save significant time and excessive effort spent by…

Computation and Language · Computer Science 2021-07-23 Byung-Hak Kim , Varun Ganapathi
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