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In this paper, we present multimodal deep neural network frameworks for age and gender classification, which take input a profile face image as well as an ear image. Our main objective is to enhance the accuracy of soft biometric trait…

Computer Vision and Pattern Recognition · Computer Science 2019-07-25 Dogucan Yaman , Fevziye Irem Eyiokur , Hazım Kemal Ekenel

The identification of reproducible biological patterns from high-dimensional data is a bottleneck for understanding the biology of complex illnesses such as schizophrenia. To address this, we developed a biologically informed, multi-stage…

Quantitative Methods · Quantitative Biology 2017-12-04 Junfang Chen , Emanuel Schwarz

Biomechanical modeling of tissue deformation can be used to simulate different scenarios of longitudinal brain evolution. In this work,we present a deep learning framework for hyper-elastic strain modelling of brain atrophy, during healthy…

Neurons and Cognition · Quantitative Biology 2021-08-19 Mariana Da Silva , Carole H. Sudre , Kara Garcia , Cher Bass , M. Jorge Cardoso , Emma C. Robinson

While utilizing machine learning models, one of the most crucial aspects is how bias and fairness affect model outcomes for diverse demographics. This becomes especially relevant in the context of machine learning for medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-10-19 Mahsa Dibaji , Neha Gianchandani , Akhil Nair , Mansi Singhal , Roberto Souza , Mariana Bento

Accurate estimation of stellar parameters -- stellar age, lifetime, and evolutionary stage -- remains a fundamental challenge in astrophysics. We introduce a hybrid deep learning architecture combining multimodal spectroscopic and…

Instrumentation and Methods for Astrophysics · Physics 2025-11-25 Jing Rou Puah , Sasa Arsovski

Aggregating multi-site brain MRI data can enhance deep learning model training, but also introduces non-biological heterogeneity caused by site-specific variations (e.g., differences in scanner vendors, acquisition parameters, and imaging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Mengqi Wu , Yongheng Sun , Qianqian Wang , Pew-Thian Yap , Mingxia Liu

Both functional and structural magnetic resonance imaging (fMRI and sMRI) are widely used for the diagnosis of mental disorder. However, combining complementary information from these two modalities is challenging due to their…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Ziyu Zhou , Anton Orlichenko , Gang Qu , Zening Fu , Vince D Calhoun , Zhengming Ding , Yu-Ping Wang

This article introduces a predictor-dependent joint modeling framework for network data obtained from multiple subjects over a shared set of nodes with spatial co-ordinates and spatially correlated nodal attributes. The framework is highly…

Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's disease (AD) and thus enrolling MCI subjects to undergo clinical trials is worthwhile. However, MCI groups usually show significant diversity and heterogeneity in the…

Quantitative Methods · Quantitative Biology 2025-08-26 Muheng Shang , Jin Zhang , Junwei Han , Lei Du

We propose an interpretable 3D Grid-Attention deep neural network that can accurately predict a person's age and whether they have Alzheimer's disease (AD) from a structural brain MRI scan. Building on a 3D convolutional neural network, we…

Tissues and Organs · Quantitative Biology 2020-11-19 Pradeep Lam , Alyssa H. Zhu , Iyad Ba Gari , Neda Jahanshad , Paul M. Thompson

This proof-of-concept study introduces a novel multimodal framework combining synchronized EEG-fNIRS modalities with neuronal avalanche analysis to identify early network dysfunction in Alzheimer's disease. The approach leverages…

Neurons and Cognition · Quantitative Biology 2026-03-25 Eva Guttmann-Flury , Yun-Hsuan Chen , Qiaoyuan Xiang , Hao Zhang , Mohamad Sawan

Multi-modal neuroimaging analysis is crucial for a comprehensive understanding of brain function and pathology, as it allows for the integration of different imaging techniques, thus overcoming the limitations of individual modalities.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Weiheng Yao , Zhihan Lyu , Mufti Mahmud , Ning Zhong , Baiying Lei , Shuqiang Wang

Recent studies have shown that multi-modeling methods can provide new insights into the analysis of brain components that are not possible when each modality is acquired separately. The joint representations of different modalities is a…

Neurons and Cognition · Quantitative Biology 2022-01-24 Jalal Mirakhorli

The process of integration of inputs from several sensory modalities in the human brain is referred to as multisensory integration. Age-related cognitive decline leads to a loss in the ability of the brain to conceive multisensory inputs.…

Signal Processing · Electrical Eng. & Systems 2023-05-02 Prerna Singh , Ayush Tripathi , Lalan Kumar , Tapan Kumar Gandhi

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

Machine Learning · Computer Science 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Objective: Longitudinal neuroimaging studies have demonstrated that adolescence is the crucial developmental epoch of continued brain growth and change. A large number of researchers dedicate to uncovering the mechanisms about brain…

Neurons and Cognition · Quantitative Biology 2019-06-19 Junqi Wang , Li Xiao , Tony W. Wilson , Julia M. Stephen , Vince D. Calhoun , Yu-Ping Wang

Multi-modal magnetic resonance imaging (MRI) is a crucial method for analyzing the human brain. It is usually used for diagnosing diseases and for making valuable decisions regarding the treatments - for instance, checking for gliomas in…

Image and Video Processing · Electrical Eng. & Systems 2021-05-26 Ashwin Nalwade , Jackie Kisa

Ageing impacts the brain's structural and functional organization and over time leads to various disorders, such as Alzheimer's disease and cognitive impairment. The process also impacts sensory function, bringing about a general slowing in…

Neurons and Cognition · Quantitative Biology 2022-09-07 L. J. Fosque , A. Alipour , M. Zare , R. V. Williams-Garcia , J. M. Beggs , G. Ortiz

Background: While deep learning technology, which has the capability of obtaining latent representations based on large-scale data, can be a potential solution for the discovery of a novel aging biomarker, existing deep learning methods for…

Machine Learning · Computer Science 2023-02-02 Seong-Eun Moon , Ji Won Yoon , Shinyoung Joo , Yoohyung Kim , Jae Hyun Bae , Seokho Yoon , Haanju Yoo , Young Min Cho