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Integrating large language models (LLMs) with knowledge graphs derived from domain-specific data represents an important advancement towards more powerful and factual reasoning. As these models grow more capable, it is crucial to enable…

Artificial Intelligence · Computer Science 2024-04-19 Stefan Dernbach , Khushbu Agarwal , Alejandro Zuniga , Michael Henry , Sutanay Choudhury

We introduce Biomed-Enriched, a biomedical text dataset constructed from PubMed via a two-stage annotation process. In the first stage, a large language model annotates 400K paragraphs from PubMed scientific articles, assigning scores for…

Computation and Language · Computer Science 2025-06-26 Rian Touchent , Nathan Godey , Eric de la Clergerie

In recent years, multimodal large language models (MLLMs) have made significant strides by training on vast high-quality image-text datasets, enabling them to generally understand images well. However, the inherent difficulty in explicitly…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Yuanze Lin , Yunsheng Li , Dongdong Chen , Weijian Xu , Ronald Clark , Philip Torr , Lu Yuan

Through additional training, we explore embedding specialized scientific knowledge into the Llama 2 Large Language Model (LLM). Key findings reveal that effective knowledge integration requires reading texts from multiple perspectives,…

Computation and Language · Computer Science 2023-12-19 Kan Hatakeyama-Sato , Yasuhiko Igarashi , Shun Katakami , Yuta Nabae , Teruaki Hayakawa

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

Biomedical Named Entity Recognition (NER) is a fundamental task of Biomedical Natural Language Processing for extracting relevant information from biomedical texts, such as clinical records, scientific publications, and electronic health…

Computation and Language · Computer Science 2023-12-27 Fahime Shahrokh , Nasser Ghadiri , Rasoul Samani , Milad Moradi

Large pre-trained language models achieve state-of-the-art results when fine-tuned on downstream NLP tasks. However, they almost exclusively focus on text-only representation, while neglecting cell-level layout information that is important…

Computation and Language · Computer Science 2021-05-25 Chenliang Li , Bin Bi , Ming Yan , Wei Wang , Songfang Huang , Fei Huang , Luo Si

The widespread adoption of Low-Rank Adaptation (LoRA) has enabled large language models (LLMs) to acquire domain-specific knowledge with remarkable efficiency. However, understanding how such a fine-tuning mechanism alters a model's…

Machine Learning · Computer Science 2025-09-26 Yucheng Wang , Ziyang Chen , Md Faisal Kabir

Domain adaptation is a widely used method in natural language processing (NLP) to improve the performance of a language model within a specific domain. This method is particularly common in the biomedical domain, which sees regular…

Computation and Language · Computer Science 2024-09-05 Mathieu Laï-king , Patrick Paroubek

Large language models have been extensively studied as neural knowledge bases for their knowledge access, editability, reasoning, and explainability. However, few works focus on the structural patterns of their knowledge. Motivated by this…

Computation and Language · Computer Science 2025-05-28 Utkarsh Sahu , Zhisheng Qi , Yongjia Lei , Ryan A. Rossi , Franck Dernoncourt , Nesreen K. Ahmed , Mahantesh M Halappanavar , Yao Ma , Yu Wang

Recent advancements in biological research leverage the integration of molecules, proteins, and natural language to enhance drug discovery. However, current models exhibit several limitations, such as the generation of invalid molecular…

Computation and Language · Computer Science 2024-01-30 Qizhi Pei , Wei Zhang , Jinhua Zhu , Kehan Wu , Kaiyuan Gao , Lijun Wu , Yingce Xia , Rui Yan

Recent advances in natural language processing (NLP) have been driven bypretrained language models like BERT, RoBERTa, T5, and GPT. Thesemodels excel at understanding complex texts, but biomedical literature, withits domain-specific…

Computation and Language · Computer Science 2025-07-28 K. Sahit Reddy , N. Ragavenderan , Vasanth K. , Ganesh N. Naik , Vishalakshi Prabhu , Nagaraja G. S

Large language models (LLMs) have demonstrated remarkable advances in reasoning capabilities. However, their performance remains constrained by limited access to explicit and structured domain knowledge. Retrieval-Augmented Generation (RAG)…

Computation and Language · Computer Science 2025-10-20 Junlin Wu , Xianrui Zhong , Jiashuo Sun , Bolian Li , Bowen Jin , Jiawei Han , Qingkai Zeng

As two important textual modalities in electronic health records (EHR), both structured data (clinical codes) and unstructured data (clinical narratives) have recently been increasingly applied to the healthcare domain. Most existing…

Computation and Language · Computer Science 2022-11-01 Sicen Liu , Xiaolong Wang , Yongshuai Hou , Ge Li , Hui Wang , Hui Xu , Yang Xiang , Buzhou Tang

Biomedical semantic question answering rooted in information retrieval can play a crucial role in keeping up to date with vast, rapidly evolving and ever-growing biomedical literature. A robust system can help researchers, healthcare…

Information Retrieval · Computer Science 2025-07-09 Shashank Verma , Fengyi Jiang , Xiangning Xue

Drug repurposing is more relevant than ever due to drug development's rising costs and the need to respond to emerging diseases quickly. Knowledge graph embedding enables drug repurposing using heterogeneous data sources combined with…

Retrieval-augmented generation (RAG) enhances the question-answering (QA) abilities of large language models (LLMs) by integrating external knowledge. However, adapting general-purpose RAG systems to specialized fields such as science and…

Computation and Language · Computer Science 2025-01-28 Ran Xu , Hui Liu , Sreyashi Nag , Zhenwei Dai , Yaochen Xie , Xianfeng Tang , Chen Luo , Yang Li , Joyce C. Ho , Carl Yang , Qi He

Large Language Models (LLMs) have shown remarkable capabilities across various domains, yet they struggle with knowledge-intensive tasks in areas that demand factual accuracy, e.g. industrial automation and healthcare. Key limitations…

Machine Learning · Computer Science 2025-09-10 Michael Banf , Johannes Kuhn

Passage re-ranking is to obtain a permutation over the candidate passage set from retrieval stage. Re-rankers have been boomed by Pre-trained Language Models (PLMs) due to their overwhelming advantages in natural language understanding.…

Information Retrieval · Computer Science 2022-04-26 Qian Dong , Yiding Liu , Suqi Cheng , Shuaiqiang Wang , Zhicong Cheng , Shuzi Niu , Dawei Yin

Clinical decision-making requires synthesizing heterogeneous evidence, including patient histories, clinical guidelines, and trajectories of comparable cases. While large language models (LLMs) offer strong reasoning capabilities, they…

Artificial Intelligence · Computer Science 2026-03-03 Shuheng Chen , Namratha Patil , Haonan Pan , Angel Hsing-Chi Hwang , Yao Du , Ruishan Liu , Jieyu Zhao