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Large language models (LLMs) are increasingly used as raters for evaluation tasks. However, their reliability is often limited for subjective tasks, when human judgments involve subtle reasoning beyond annotation labels. Thinking traces,…

Artificial Intelligence · Computer Science 2026-02-23 Xingjian Zhang , Tianhong Gao , Suliang Jin , Tianhao Wang , Teng Ye , Eytan Adar , Qiaozhu Mei

Sepsis, a life-threatening inflammatory response to infection, causes organ dysfunction, making early detection and optimal management critical. Previous reinforcement learning (RL) approaches to sepsis management rely primarily on…

Machine Learning · Computer Science 2025-08-12 Yooseok Lim , ByoungJun Jeon , Seong-A Park , Jisoo Lee , Sae Won Choi , Chang Wook Jeong , Ho-Geol Ryu , Hongyeol Lee , Hyun-Lim Yang

Target trial emulation (TTE) enables causal questions to be studied with observational data when randomized controlled trials (RCTs) are infeasible. Yet treatment-effect methods often address causal estimation, missingness, and temporal…

Understanding when and how linguistic knowledge emerges during language model training remains a central challenge for interpretability. Most existing tools are post hoc, rely on scalar metrics, or require nontrivial integration effort,…

Computation and Language · Computer Science 2025-07-08 Nura Aljaafari , Danilo S. Carvalho , André Freitas

Clinical language processing has received a lot of attention in recent years, resulting in new models or methods for disease phenotyping, mortality prediction, and other tasks. Unfortunately, many of these approaches are tested under…

Computation and Language · Computer Science 2022-09-30 Travis R. Goodwin , Dina Demner-Fushman

Recent advances in Large Language Models (LLMs) have led to remarkable progresses in medical consultation. However, existing medical LLMs overlook the essential role of Electronic Health Records (EHR) and focus primarily on diagnosis…

Artificial Intelligence · Computer Science 2025-06-26 Weijieying Ren , Tianxiang Zhao , Lei Wang , Tianchun Wang , Vasant Honavar

Brief hospital course (BHC) summaries are clinical documents that summarize a patient's hospital stay. While large language models (LLMs) depict remarkable capabilities in automating real-world tasks, their capabilities for healthcare…

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Most of the existing medication recommendation models are predicted with only structured data such as medical codes, with the remaining other large amount of unstructured or semi-structured data underutilization. To increase the utilization…

Computation and Language · Computer Science 2024-07-16 Yu-Tzu Lee

Deep-learning-based clinical decision support using structured electronic health records (EHR) has been an active research area for predicting risks of mortality and diseases. Meanwhile, large amounts of narrative clinical notes provide…

Computation and Language · Computer Science 2023-05-10 Weimin Lyu , Xinyu Dong , Rachel Wong , Songzhu Zheng , Kayley Abell-Hart , Fusheng Wang , Chao Chen

With the advent of artificial intelligence (AI), many researchers are attempting to extract structured information from document-level biomedical literature by fine-tuning large language models (LLMs). However, they face significant…

Neural and Evolutionary Computing · Computer Science 2026-02-26 Lei Zhao , Ling Kang , Quan Guo

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

The development of Electronic Health Records summarization systems has revolutionized patient data management. Previous research advanced this field by adapting Large Language Models for clinical tasks, using diverse datasets to generate…

Computation and Language · Computer Science 2024-10-15 Ruvarashe Madzime , Clement Nyirenda

Nowadays, success of financial organizations heavily depends on their ability to process digital traces generated by their clients, e.g., transaction histories, gathered from various sources to improve user modeling pipelines. As…

We study clinical trial table reasoning, where answers are not directly stored in visible cells but must be reasoned from semantic understanding through normalization, classification, extraction, or lightweight domain reasoning. Motivated…

High computation costs and latency of large language models such as GPT-4 have limited their deployment in clinical settings. Small language models (SLMs) offer a cost-effective alternative, but their limited capacity requires biomedical…

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Data consistency between unstructured clinical notes and structured tables in Electronic Health Records (EHRs) is essential for patient safety and clinical decision-making. However, existing work on note-table consistency verification…

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

Objective: Recent advances in language models have shown potential to adapt professional-facing biomedical literature to plain language, making it accessible to patients and caregivers. However, their unpredictability, combined with the…

Computation and Language · Computer Science 2025-07-23 Brian Ondov , William Xia , Kush Attal , Ishita Unde , Jerry He , Dina Demner-Fushman