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Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Large Language Models (LLMs) have emerged as powerful tools for generating data across various modalities. By transforming data from a scarce resource into a controllable asset, LLMs mitigate the bottlenecks imposed by the acquisition costs…

In recent years, several models have improved the capacity to generate synthetic tabular datasets. However, such models focus on synthesizing simple columnar tables and are not useable on real-life data with complex structures. This paper…

Machine Learning · Computer Science 2022-02-07 Luca Canale , Nicolas Grislain , Grégoire Lothe , Johan Leduc

Despite technological and medical advances, the detection, interpretation, and treatment of cancer based on imaging data continue to pose significant challenges. These include inter-observer variability, class imbalance, dataset shifts,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Richard Osuala , Kaisar Kushibar , Lidia Garrucho , Akis Linardos , Zuzanna Szafranowska , Stefan Klein , Ben Glocker , Oliver Diaz , Karim Lekadir

Data-driven technologies have improved the efficiency, reliability and effectiveness of healthcare services, but come with an increasing demand for data, which is challenging due to privacy-related constraints on sharing data in healthcare…

Access to electronic health records (EHRs) for digital health research is often limited by privacy regulations and institutional barriers. Synthetic EHRs have been proposed as a way to enable safe and sovereign data sharing; however,…

Machine Learning · Computer Science 2026-03-10 Guanglin Zhou , Armin Catic , Motahare Shabestari , Matthew Young , Chaiquan Li , Katrina Poppe , Sebastiano Barbieri

Synthetic data generation is one approach for sharing individual-level data. However, to meet legislative requirements, it is necessary to demonstrate that the individuals' privacy is adequately protected. There is no consolidated standard…

Recent breakthroughs in synthetic data generation approaches made it possible to produce highly photorealistic images which are hardly distinguishable from real ones. Furthermore, synthetic generation pipelines have the potential to…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Alon Shoshan , Nadav Bhonker , Igor Kviatkovsky , Matan Fintz , Gerard Medioni

We consider the task of meta-analysis in high-dimensional settings in which the data sources are similar but non-identical. To borrow strength across such heterogeneous datasets, we introduce a global parameter that emphasizes…

Methodology · Statistics 2022-07-01 Subha Maity , Yuekai Sun , Moulinath Banerjee

Synthetic Electronic Health Records (EHRs) offer a valuable opportunity to create privacy preserving and harmonized structured data, supporting numerous applications in healthcare. Key benefits of synthetic data include precise control over…

Computation and Language · Computer Science 2025-04-28 Yihan Lin , Zhirong Bella Yu , Simon Lee

Synthetic data has gained significant momentum thanks to sophisticated machine learning tools that enable the synthesis of high-dimensional datasets. However, many generation techniques do not give the data controller control over what…

Cryptography and Security · Computer Science 2022-11-22 Florimond Houssiau , Samuel N. Cohen , Lukasz Szpruch , Owen Daniel , Michaela G. Lawrence , Robin Mitra , Henry Wilde , Callum Mole

The success of AI models relies on the availability of large, diverse, and high-quality datasets, which can be challenging to obtain due to data scarcity, privacy concerns, and high costs. Synthetic data has emerged as a promising solution…

Computation and Language · Computer Science 2024-08-13 Ruibo Liu , Jerry Wei , Fangyu Liu , Chenglei Si , Yanzhe Zhang , Jinmeng Rao , Steven Zheng , Daiyi Peng , Diyi Yang , Denny Zhou , Andrew M. Dai

Recent advances in generative modelling have led many to see synthetic data as the go-to solution for a range of problems around data access, scarcity, and under-representation. In this paper, we study three prominent use cases: (1) Sharing…

Machine Learning · Computer Science 2026-02-04 Bogdan Kulynych , Theresa Stadler , Jean Louis Raisaro , Carmela Troncoso

The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Joshua Niemeijer , Jan Ehrhardt , Hristina Uzunova , Heinz Handels

Synthetic data sets are used across linguistic domains and NLP tasks, particularly in scenarios where authentic data is limited (or even non-existent). One such domain is that of clinical (healthcare) contexts, where there exist significant…

Computation and Language · Computer Science 2026-03-17 Steven Bedrick , A. Seza Doğruöz , Sergiu Nisioi

Generative models capable of capturing nuanced clinical features in medical images hold great promise for facilitating clinical data sharing, enhancing rare disease datasets, and efficiently synthesizing annotated medical images at scale.…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 Shenghuan Sun , Gregory M. Goldgof , Atul Butte , Ahmed M. Alaa

Modern studies of societal phenomena rely on the availability of large datasets capturing attributes and activities of synthetic, city-level, populations. For instance, in epidemiology, synthetic population datasets are necessary to study…

Databases · Computer Science 2016-02-26 Hao Wu , Yue Ning , Prithwish Chakraborty , Jilles Vreeken , Nikolaj Tatti , Naren Ramakrishnan

Synthetic data generation, leveraging generative machine learning techniques, offers a promising approach to mitigating privacy concerns associated with real-world data usage. Synthetic data closely resembles real-world data while…

Machine Learning · Computer Science 2025-08-25 Weijie Niu , Alberto Huertas Celdran , Karoline Siarsky , Burkhard Stiller

Synthetic data holds substantial potential to address practical challenges in epidemiology due to restricted data access and privacy concerns. However, many current methods suffer from limited quality, high computational demands, and…

Synthetic healthcare data generation presents a viable approach to enhance data accessibility and support research by overcoming limitations associated with real-world medical datasets. However, ensuring fairness across protected attributes…

Machine Learning · Computer Science 2025-11-04 Sama Salarian , Yue Zhang , Swati Padhee , Srinivasan Parthasarathy