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Interatomic potentials (IPs) with wide elemental coverage and high accuracy are powerful tools for high-throughput materials discovery. While the past few years witnessed the development of multiple new universal IPs that cover wide ranges…

Materials Science · Physics 2025-09-11 Shusuke Ito , Koki Muraoka , Akira Nakayama

When creating training data for machine-learned interatomic potentials (MLIPs), it is common to create initial structures and evolve them using molecular dynamics to sample a larger configuration space. We benchmark two other modalities of…

Chemical Physics · Physics 2022-12-09 Michael J. Waters , James M. Rondinelli

In recent years, machine learning interatomic potentials (MLIPs) have attracted significant attention as a method that enables large-scale, long-time atomistic simulations while maintaining accuracy comparable to electronic structure…

Materials Science · Physics 2025-03-27 Yuta Yoshimoto , Naoki Matsumura , Yuto Iwasaki , Hiroshi Nakao , Yasufumi Sakai

Frontier models increasingly adopt Mixture-of-Experts (MoE) architectures to achieve large-model performance at reduced cost. However, training MoE models on HPC platforms is hindered by large memory footprints, frequent large-scale…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-07 Sajal Dash , Feiyi Wang

Machine learning interatomic potentials (MLIPs) achieve excellent accuracy when trained on large Density Functional Theory (DFT) data. To be useful in practice, they must often be adapted to target chemistries using small and expensive…

Recent advancements in multimodal pre-training models have significantly advanced computational pathology. However, current approaches predominantly rely on visual-language models, which may impose limitations from a molecular perspective…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Minghao Han , Dingkang Yang , Jiabei Cheng , Xukun Zhang , Linhao Qu , Zizhi Chen , Lihua Zhang

Pretrained universal machine-learning interatomic potentials (MLIPs) have revolutionized computational materials science by enabling rapid atomistic simulations as efficient alternatives to ab initio methods. Fine-tuning pretrained MLIPs…

Materials Science · Physics 2025-06-19 Jisu Kim , Jiho Lee , Sangmin Oh , Yutack Park , Seungwoo Hwang , Seungwu Han , Sungwoo Kang , Youngho Kang

A common practice in metric learning is to train and test an embedding model for each dataset. This dataset-specific approach fails to simulate real-world scenarios that involve multiple heterogeneous distributions of data. In this regard,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Sungyeon Kim , Donghyun Kim , Suha Kwak

Developing machine learning interatomic potentials (MLIPs) for complex materials systems remains challenging because it requires expertise in atomistic simulations, machine learning, and workflow design, as well as iterative active learning…

Machine Learning · Computer Science 2026-05-15 Wenwen Li , Yuki Orimo , Nontawat Charoenphakdee

Recent advancements in Multimodal Large Language Models (MLLMs) underscore the significance of scalable models and data to boost performance, yet this often incurs substantial computational costs. Although the Mixture of Experts (MoE)…

Artificial Intelligence · Computer Science 2024-05-21 Yunxin Li , Shenyuan Jiang , Baotian Hu , Longyue Wang , Wanqi Zhong , Wenhan Luo , Lin Ma , Min Zhang

Effective adaptation to distribution shifts in training data is pivotal for sustaining robustness in neural networks, especially when removing specific biases or outdated information, a process known as machine unlearning. Traditional…

Machine Learning · Computer Science 2024-05-24 Ling Han , Hao Huang , Dustin Scheinost , Mary-Anne Hartley , María Rodríguez Martínez

Transition-state searches are central to understanding reaction mechanisms, but the high computational cost of density-functional theory (DFT) limits their application in high-throughput catalyst and materials discovery. Machine-learned…

Chemical Physics · Physics 2026-04-02 Jonah Marks , Jonathon Vandezande , Joseph Gomes

Meta-learning, which pursues an effective initialization model, has emerged as a promising approach to handling unseen tasks. However, a limitation remains to be evident when a meta-learner tries to encompass a wide range of task…

Machine Learning · Computer Science 2024-03-12 Jae-Jun Lee , Sung Whan Yoon

Artificial neural networks with millions of adjustable parameters and a similar number of training examples are a potential solution for difficult, large-scale pattern recognition problems in areas such as speech and face recognition,…

Machine Learning · Computer Science 2019-11-14 Douglas Aberdeen , Jonathan Baxter , Robert Edwards

Machine learning interatomic potentials (MLIPs) can predict energy, force, and stress of materials and enable a wide range of downstream discovery tasks. A key design choice in MLIPs involves the trade-off between invariant and equivariant…

Machine learning interatomic potentials (MLIPs) are routinely used atomic simulations, but generating databases of atomic configurations used in fitting these models is a laborious process, requiring significant computational and human…

Materials Science · Physics 2022-07-26 Connor Allen , Albert P. Bartók

The core of molecular dynamics simulation fundamentally lies in the interatomic potential. Traditional empirical potentials lack accuracy, while first-principles methods are computationally prohibitive. Machine learning interatomic…

Machine Learning · Computer Science 2026-03-25 Shuyu Bi , Zhede Zhao , Qiangchao Sun , Tao Hu , Xionggang Lu , Hongwei Cheng

Machine learning interatomic potentials (MLIPs) have proven to be wildly useful for molecular dynamics simulations, powering countless drug and materials discovery applications. However, MLIPs face two primary bottlenecks preventing them…

Machine Learning · Computer Science 2026-01-30 Kevin Han , Haolin Cong , Bowen Deng , Amir Barati Farimani

Machine-learned interatomic potentials (MLIPs) have rapidly progressed in accuracy, speed, and data efficiency in recent years. However, training robust MLIPs in multicomponent systems still remains a challenge. In this work, we train a…

Machine-learning potentials (MLPs) for atomistic simulations are a promising alternative to conventional classical potentials. Current approaches rely on descriptors of the local atomic environment with dimensions that increase…

Materials Science · Physics 2017-12-05 Nongnuch Artrith , Alexander Urban , Gerbrand Ceder