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Photoacoustic tomography (PAT) has the potential to recover morphological and functional tissue properties with high spatial resolution. However, previous attempts to solve the optical inverse problem with supervised machine learning were…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Melanie Schellenberg , Janek Gröhl , Kris K. Dreher , Jan-Hinrich Nölke , Niklas Holzwarth , Minu D. Tizabi , Alexander Seitel , Lena Maier-Hein

Photoacoustic tomography is a hybrid imaging technique that combines high optical tissue contrast with high ultrasound resolution. Direct reconstruction methods such as filtered backprojection, time reversal and least squares suffer from…

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio

Self-supervised blind denoising for Poisson-Gaussian noise remains a challenging task. Pseudo-supervised pairs constructed from single noisy images re-corrupt the signal and degrade the performance. The visible blindspots solve the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Zejin Wang , Jiazheng Liu , Hao Zhai , Hua Han

Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Bowei Yao , Yi Zeng , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Yuyao Zhang , Jingyi Yu , Xiran Cai

Idier et al. [IEEE Trans. Comput. Imaging 4(1), 2018] propose a method which achieves superresolution in the microscopy setting by leveraging random speckle illumination and knowledge about statistical second order moments for the…

Signal Processing · Electrical Eng. & Systems 2022-02-02 Osman Asif Malik , Venkatalakshmi Vyjayanthi Narumanchi , Stephen Becker , Todd W. Murray

Noisy supervision refers to supervising image restoration learning with noisy targets. It can alleviate the data collection burden and enhance the practical applicability of deep learning techniques. However, existing methods suffer from…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Haosen Liu , Jiahao Liu , Shan Tan , Edmund Y. Lam

We study the deep image prior (DIP) framework applied to photoacoustic tomography (PAT) as an unsupervised reconstruction approach to mitigate limited-view artifacts and noise commonly encountered in experimental settings. Efficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-22 Hanna Pulkkinen , Jenni Poimala , Leonid Kunyansky , Janek Gröhl , Andreas Hauptmann

Propagation-based X-ray phase-contrast imaging (PBI) enables high-contrast visualization of lung structures and holds strong medical potential. However, safe translation to the clinic will require a substantial radiation dose reduction,…

Ultrafast electron beam X-ray computed tomography produces noisy data due to short measurement times, causing reconstruction artifacts and limiting overall image quality. To counteract these issues, two self-supervised deep learning methods…

Machine Learning · Computer Science 2025-11-24 Israt Jahan Tulin , Sebastian Starke , Dominic Windisch , André Bieberle , Peter Steinbach

We address the problem of image reconstruction from incomplete measurements, encompassing both upsampling and inpainting, within a learning-based framework. Conventional supervised approaches require fully sampled ground truth data, while…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Benjamin Walder , Daniel Toader , Robert Nuster , Günther Paltauf , Peter Burgholzer , Gregor Langer , Lukas Krainer , Markus Haltmeier

The quality of the reconstructed photoacoustic image largely depends on the amount of photoacoustic (PA) boundary data available, which in turn is proportional to the number of detectors employed. In case of limited data (owing to less…

Image and Video Processing · Electrical Eng. & Systems 2020-01-20 Navchetan Awasthi , Rohit Pardasani , Sandeep Kumar Kalva , Manojit Pramanik , Phaneendra K. Yalavarthy

Self-supervised image denoising techniques emerged as convenient methods that allow training denoising models without requiring ground-truth noise-free data. Existing methods usually optimize loss metrics that are calculated from multiple…

Learning based methods are now ubiquitous for solving inverse problems, but their deployment in real-world applications is often hindered by the lack of ground truth references for training. Recent self-supervised learning strategies offer…

Image and Video Processing · Electrical Eng. & Systems 2026-02-27 Victor Sechaud , Laurent Jacques , Patrice Abry , Julián Tachella

We study the inverse source problem in photoacoustic tomography (PAT) for mixed data, which denote a weighted linear combination of the acoustic pressure and its normal derivative on an observation surface. We consider in particular the…

Analysis of PDEs · Mathematics 2022-07-06 Florian Dreier , Markus Haltmeier

Purpose: Photoacoustic tomography (PAT) is a novel imaging technique that can spatially resolve both morphological and functional tissue properties, such as the vessel topology and tissue oxygenation. While this capacity makes PAT a…

Training deep neural networks has become a common approach for addressing image restoration problems. An alternative for training a "task-specific" network for each observation model is to use pretrained deep denoisers for imposing only the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Tomer Garber , Tom Tirer

Supervised neural networks are known to achieve excellent results in various image restoration tasks. However, such training requires datasets composed of pairs of corrupted images and their corresponding ground truth targets.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-21 Gregory Vaksman , Michael Elad

Machine learning has achieved impressive performance in tomographic reconstruction, but supervised training requires paired measurements and ground-truth images that are often unavailable. This has motivated self-supervised approaches,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Markus Haltmeier , Lukas Neumann , Nadja Gruber , Gyeongha Hwang

Low-count positron emission tomography (PET) reconstruction is a challenging inverse problem due to severe degradations arising from Poisson noise, photon scarcity, and attenuation correction errors. Existing deep learning methods typically…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Zheng Zhang , Hao Tang , Yingying Hu , Zhanli Hu , Jing Qin