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Chest X-ray plays a central role in thoracic diagnosis, and its interpretation inherently requires multi-step, evidence-grounded reasoning. However, large vision-language models (LVLMs) often generate plausible responses that are not…

Artificial Intelligence · Computer Science 2026-03-25 Hyungyung Lee , Hangyul Yoon , Edward Choi

Precision therapeutics require multimodal adaptive models that generate personalized treatment recommendations. We introduce TxAgent, an AI agent that leverages multi-step reasoning and real-time biomedical knowledge retrieval across a…

Artificial Intelligence · Computer Science 2025-03-17 Shanghua Gao , Richard Zhu , Zhenglun Kong , Ayush Noori , Xiaorui Su , Curtis Ginder , Theodoros Tsiligkaridis , Marinka Zitnik

Dermatological diagnosis requires integrating fine-grained visual perception with expert clinical knowledge. Although Multimodal Large Language Models (MLLMs) facilitate interactive medical image analysis, their application in dermatology…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Yize Liu , Siyuan Yan , Ming Hu , Lie Ju , Xieji Li , Feilong Tang , Wei Feng , Zongyuan Ge

3D CT analysis spans a continuum from low-level perception to high-level clinical understanding. Existing 3D-oriented analysis methods adopt either isolated task-specific modeling or task-agnostic end-to-end paradigms to produce one-hop…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Ziyue Wang , Linghan Cai , Chang Han Low , Haofeng Liu , Junde Wu , Jingyu Wang , Rui Wang , Lei Song , Jiang Bian , Jingjing Fu , Yueming Jin

Reliable interpretation of echocardiography (Echo) is crucial for assessing cardiac function, which demands clinicians to synchronously orchestrate multiple capabilities, including visual observation (eyes), manual measurement (hands), and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Qin Wang , Zhiqing He , Yu Liu , Bowen Guo , Zeju Li , Miao Zhao , Wenhao Ju , Zhiling Luo , Xianhong Shu , Yi Guo , Yuanyuan Wang

Recent multimodal LLMs have shown promise in chart-based visual question answering, but their performance declines sharply on unannotated charts-those requiring precise visual interpretation rather than relying on textual shortcuts. To…

Artificial Intelligence · Computer Science 2026-01-08 Rachneet Kaur , Nishan Srishankar , Zhen Zeng , Sumitra Ganesh , Manuela Veloso

PET theranostics is transforming precision oncology, yet treatment response varies substantially; many patients receiving 177Lu-PSMA radioligand therapy (RLT) for metastatic castration-resistant prostate cancer (mCRPC) fail to respond,…

Deep learning has advanced medical image classification, but interpretability challenges hinder its clinical adoption. This study enhances interpretability in Chest X-ray (CXR) classification by using concept bottleneck models (CBMs) and a…

Information Retrieval · Computer Science 2025-04-30 Hasan Md Tusfiqur Alam , Devansh Srivastav , Md Abdul Kadir , Daniel Sonntag

Objective Renal cancer is a common malignancy and a major cause of cancer-related deaths. Computed tomography (CT) is central to early detection, staging, and treatment planning. However, the growing CT workload increases radiologists'…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Renjie Liang , Zhengkang Fan , Jinqian Pan , Chenkun Sun , Bruce Daniel Steinberg , Russell Terry , Jie Xu

Chest radiography is widely used in diagnostic imaging. However, perceptual errors -- especially overlooked but visible abnormalities -- remain common and clinically significant. Current workflows and AI systems provide limited support for…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Adhrith Vutukuri , Akash Awasthi , David Yang , Carol C. Wu , Hien Van Nguyen

This paper focuses on embodied task planning, where an agent acquires visual observations from the environment and executes atomic actions to accomplish a given task. Although recent Vision-Language Models (VLMs) have achieved impressive…

Robotics · Computer Science 2026-04-10 Peiran Xu , Jiaqi Zheng , Yadong Mu

Chest computed tomography (CT) is central to the detection and management of thoracic disease, yet the growing scale and complexity of volumetric imaging increasingly exceed what can be addressed by scan-level prediction alone. Clinically…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Xuguang Bai , Mingxuan Liu , Tongxi Song , Yifei Chen , Hongjia Yang , Kasidit Anmahapong , Zihan Li , Ying Zhou , Qiyuan Tian

Computer-aided diagnosis (CAD) has significantly advanced automated chest X-ray diagnosis but remains isolated from clinical workflows and lacks reliable decision support and interpretability. Human-AI collaboration seeks to enhance the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Shaoxuan Wu , Jingkun Chen , Chong Ma , Cong Shen , Xiao Zhang , Jun Feng

Automatic radiology report generation is a promising application of multimodal deep learning, aiming to reduce reporting workload and improve consistency. However, current state-of-the-art (SOTA) systems - such as Multimodal AI for…

Radiology report generation (RRG) aims to automatically produce diagnostic reports from medical images, with the potential to enhance clinical workflows and reduce radiologists' workload. While recent approaches leveraging multimodal large…

Artificial Intelligence · Computer Science 2025-05-16 Ziruo Yi , Ting Xiao , Mark V. Albert

Chest radiographs are one of the most common diagnostic modalities in clinical routine. It can be done cheaply, requires minimal equipment, and the image can be diagnosed by every radiologists. However, the number of chest radiographs…

Computer Vision and Pattern Recognition · Computer Science 2021-09-16 Benjamin Hou , Georgios Kaissis , Ronald Summers , Bernhard Kainz

Recent advances in reasoning-enhanced large language models (LLMs) and multimodal LLMs (MLLMs) have significantly improved performance in complex tasks, yet medical AI models often overlook the structured reasoning processes inherent in…

Artificial Intelligence · Computer Science 2025-05-22 Ziqing Fan , Cheng Liang , Chaoyi Wu , Ya Zhang , Yanfeng Wang , Weidi Xie

Analyzing whole-slide images (WSIs) requires an iterative, evidence-driven reasoning process that parallels how pathologists dynamically zoom, refocus, and self-correct while collecting the evidence. However, existing computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Jingyun Chen , Linghan Cai , Zhikang Wang , Yi Huang , Songhan Jiang , Shenjin Huang , Hongpeng Wang , Yongbing Zhang

The development of AI-based methods to analyze radiology reports could lead to significant advances in medical diagnosis, from improving diagnostic accuracy to enhancing efficiency and reducing workload. However, the lack of…

Computation and Language · Computer Science 2025-08-14 Yuyan Ge , Kwan Ho Ryan Chan , Pablo Messina , René Vidal

Medical image analysis is crucial in modern radiological diagnostics, especially given the exponential growth in medical imaging data. The demand for automated report generation systems has become increasingly urgent. While prior research…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Hao Chen , Wei Zhao , Yingli Li , Tianyang Zhong , Yisong Wang , Youlan Shang , Lei Guo , Junwei Han , Tianming Liu , Jun Liu , Tuo Zhang