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Neurons perform computations, and convey the results of those computations through the statistical structure of their output spike trains. Here we present a practical method, grounded in the information-theoretic analysis of prediction, for…

Neurons and Cognition · Quantitative Biology 2022-03-18 Robert Haslinger , Kristina Lisa Klinkner , Cosma Rohilla Shalizi

Based on a recently proposed non-equilibrium mechanism for spatial pattern formation [cond-mat/0312366] we study how morphogenesis can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of…

Molecular Networks · Quantitative Biology 2007-05-23 Thimo Rohlf , Stefan Bornholdt

Darwinian evolution tends to produce energy-efficient outcomes. On the other hand, energy limits computation, be it neural and probabilistic or digital and logical. Taking a particular energy-efficient viewpoint, we define neural…

Neurons and Cognition · Quantitative Biology 2021-04-05 William B Levy , Victoria G. Calvert

Computational experiments are exploited in finding a well-designed processing path to optimize material structures for desired properties. This requires understanding the interplay between the processing-(micro)structure-property linkages…

Computational Engineering, Finance, and Science · Computer Science 2023-05-04 Junrong Lin , Mahmudul Hasan , Pinar Acar , Jose Blanchet , Vahid Tarokh

Neurophysiologists are nowadays able to record from a large number of extracellular electrodes and to extract, from the raw data, the sequences of action potentials or spikes generated by many neurons. Unfortunately these ''many neurons''…

Applications · Statistics 2026-04-22 Pierre Charitat , Ségolen Geffray , Christophe Pouzat

Understanding individual cortical development is essential for identifying deviations linked to neurodevelopmental disorders. However, current normative modelling frameworks struggle to capture fine-scale anatomical details due to their…

Quantitative Methods · Quantitative Biology 2025-08-14 Nashira Baena , Mariana da Silva , Irina Grigorescu , Aakash Saboo , Saga Masui , Jaques-Donald Tournier , Emma C. Robinson

Nerve impulses, the currency of information flow in the brain, are generated by an instability of the neuronal membrane potential dynamics. Neuronal circuits exhibit collective chaos that appears essential for learning, memory, sensory…

Neurons and Cognition · Quantitative Biology 2024-12-31 Rainer Engelken , Michael Monteforte , Fred Wolf

Deep learning has excelled in image recognition tasks through neural networks inspired by the human brain. However, the necessity for large models to improve prediction accuracy introduces significant computational demands and extended…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Taigo Sakai , Kazuhiro Hotta

Convolutional Neural Networks (CNNs) have shown to be powerful classification tools in tasks that range from check reading to medical diagnosis, reaching close to human perception, and in some cases surpassing it. However, the problems to…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-12-08 Jose Marques , Gabriel Falcao , Luís A. Alexandre

Biological systems exhibit remarkable morphogenetic plasticity, where a single genome can encode various specialized cellular structures triggered by local chemical signals. In the domain of Deep Learning, Differentiable Neural Cellular…

Neural and Evolutionary Computing · Computer Science 2025-12-10 Ali Sakour

Minimization of cortical prediction errors has been considered a key computational goal of the cerebral cortex underlying perception, action and learning. However, it is still unclear how the cortex should form and use information about…

Neurons and Cognition · Quantitative Biology 2025-04-07 Arno Granier , Mihai A. Petrovici , Walter Senn , Katharina A. Wilmes

As a follow-up tutorial article of [29], in this paper, we will introduce the basic compositional units of the human brain, which will further illustrate the cell-level bio-structure of the brain. On average, the human brain contains about…

Neurons and Cognition · Quantitative Biology 2019-06-06 Jiawei Zhang

Cellular development follows a stochastic yet rule-governed trajectory, though the underlying principles remain elusive. Here, we propose that cellular development follows paths of least action, aligning with foundational physical laws that…

Biological Physics · Physics 2025-04-14 Rohola Zandie , Farhan Khodaee , Yufan Xia , Elazer R. Edelman

Deep neural networks is a branch in machine learning that has seen a meteoric rise in popularity due to its powerful abilities to represent and model high-level abstractions in highly complex data. One area in deep neural networks that is…

Computer Vision and Pattern Recognition · Computer Science 2015-11-11 Mohammad Javad Shafiee , Parthipan Siva , Alexander Wong

Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in…

Neurons and Cognition · Quantitative Biology 2012-03-06 Xuejuan Zhang , Jianfeng Feng

Living neural networks emerge through a process of growth and self-organization that begins with a single cell and results in a brain, an organized and functional computational device. Artificial neural networks, however, rely on…

Neural and Evolutionary Computing · Computer Science 2019-06-05 Guruprasad Raghavan , Matt Thomson

Real-time coupling of cell cultures to neuromorphic circuits necessitates a neuromorphic network that replicates biological behaviour both on a per-neuron and on a population basis, with a network size comparable to the culture. We present…

How does the size of a neural circuit influence its learning performance? Intuitively, we expect the learning capacity of a neural circuit to grow with the number of neurons and synapses. Larger brains tend to be found in species with…

Neurons and Cognition · Quantitative Biology 2019-05-09 Dhruva V Raman , Timothy O'Leary

Although individual neurons and neural populations exhibit the phenomenon of representational drift, perceptual and behavioral outputs of many neural circuits can remain stable across time scales over which representational drift is…

Networks of superconducting optoelectronic neurons are investigated for their near-term technological potential and long-term physical limitations. Networks with short average path length, high clustering coefficient, and power-law degree…

Neural and Evolutionary Computing · Computer Science 2018-05-17 Jeffrey M. Shainline , Jeff Chiles , Sonia M. Buckley , Adam N. McCaughan , Richard P. Mirin , Sae Woo Nam